Results 81 to 90 of about 9,576,015 (339)
Optimization of roughing operations in cnc machining for rapid manufacturing processes [PDF]
, 2013 This paper presents a method for optimizing roughing operations in CNC machining particularly for parts production through a subtractive rapid manufacturing process. The roughing operation in machining is primarily used to remove the bulk of the material
Case, Keith +2 more
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
SPH method applied to high speed cutting modelling [PDF]
, 2007 The purpose of this study is to introduce a new approach of high speed cutting numerical modelling. A Lagrangian smoothed particle hydrodynamics (SPH)- based model is arried out using the Ls-Dyna software.
Chieragatti, Rémy +4 more
core +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Investigation on different composition of powder metallurgy electrode (Cu-W) in high performance edm (HPEDM) on AISI D2 hardened steel [PDF]
, 2013 The ideal selection of manufacturing conditions is one of the most important aspects to take into consideration in the majority of manufacturing processes and particularly in processes related to Electrical Discharge Machining (EDM).
Abdul Hamid, Faizul Ezmat
core
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
, 2018 Milling of GFRP composite materials is a rather complex task owing to its heterogeneity and the number of problems, such as surface delamination, which appear during the machining process, associated with the characteristics of the material and the ...
M. Jenarthanan, R. Jeyapaul
semanticscholar +1 more source
Performance evaluation of electrical discharge machine on titanium alloy using copper impregnated graphite electrode [PDF]
, 2010 Electrical discharge machining (EDM) which is very prominent amongst the non conventional machining methods is expected to be used quite extensively in machining titanium alloys due to the favorable features and advantages that it offers.
Mohd. Isa @ Hamid, Mohd. Halimudin
core
Toward a better understanding of tool wear effect through a comparison between experiments and SPH numerical modelling of machining hard materials [PDF]
, 2009 The aim of this study is to improve the general understanding of tungsten carbide (WC–Co) tool wear under dry machining of the hard-to-cut titanium alloy Ti6Al4V. The chosen approach includes experimental and numerical tests.
Bil +26 more
core +7 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source