Results 11 to 20 of about 29,916 (207)
A ferrocene redox-active triazolium macrocycle that binds and senses chloride [PDF]
Beilstein Journal of Organic Chemistry, 2012 A ferrocene bis(triazole) macrocycle was synthesised in good yield by the Eglinton coupling of an acyclic bis(alkyne) precursor and characterised in the solid state by X-ray crystallography. Alkylation gives the corresponding triazolium macrocycle, which
Nicholas G. White, Paul D. Beer
doaj +3 more sources
Supramolecular complexes of dihydroazolopyrimidines with macrocyclic receptors: synthesis, rapid analysis, and evaluation [PDF]
Beilstein Journal of Organic ChemistryOne of the main challenges limiting the medical use of dihydroazolopyrimidine derivatives is their poor water solubility. However, this problem can be significantly reduced by binding to supramolecular receptors.
Daria Miasnikova +8 more
doaj +2 more sources
Performance evaluation of flexible macrocycle docking in AutoDock [PDF]
, 2022 Macrocycles represent an important class of ligands, both in natural products and designed drugs. In drug design, macrocyclizations can impart specific ligand conformations and contribute to passive permeation by encouraging intramolecular H-bonds ...
Matthew, Holcomb +3 more
core +2 more sources
Threading a linear molecule through a macrocycle thanks to boron [PDF]
, 2023 Two BODIPYs and one boron beta-diketonate were threaded through a macrocycle bearing a 2,2’-biphenol unit, showing thus the ability of boron to act as a gathering atom.
Fabienne, Berrée +7 more
core +2 more sources
Synlett, 2018 Artificial macrocycles recently became popular as a novel research field in drug discovery. As opposed to their natural twins, artificial macrocycles promise to have better control on synthesizability and control over their physicochemical properties resulting in druglike properties. Very few synthetic methods allow for the convergent, fast but diverse
Abdelraheem +3 more
openaire +2 more sources
Photosensitizers Mediated Photodynamic Inactivation against Fungi
Nanomaterials, 2021 Superficial and systemic fungal infections are essential problems for the modern health care system. One of the challenges is the growing resistance of fungi to classic antifungals and the constantly increasing cost of therapy.
Daniel Ziental +4 more
doaj +1 more source
A DNA-Encoded Macrocycle Library that Resembles Natural Macrocycles [PDF]
, 2019 Herein we perform a seven-step chemical synthesis of a DNA-encoded macrocycle library (DEML) on DNA. Inspired by polyketide and mixed peptide-polyketide natural products, the library was designed to incorporate rich backbone diversity ...
Dennis G., Gillingham +4 more
core +2 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compound, [Hg3(C6F4)3]·C6N4, contains one molecule of tetracyanoethylene B per one molecule of mercury macrocycle A, i.e., A•B, and crystallizes in the monoclinic space group C2/c.
Raúl Castañeda +2 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 Technologies for discovering peptides as potential therapeutics have rapidly advanced in recent years with significant interest from both academic and pharmaceutical labs.
Jeffrey K. Holden +4 more
doaj +1 more source
Spectral manifestation of substitution of out-of-plane ligands in metallophtalocyanines
EPJ Web of Conferences, 2017 In our study, we demonstrate the splitting effect of long-wavelength bands in absorption spectra (excitation of fluorescence) of the series of Zn(II), Ti(IV), Zr(IV) and Hf(IV) phthalocyanines at low temperatures.
Starukhin A. +6 more
doaj +1 more source