Results 21 to 30 of about 13,257 (251)
Formation of a macrocycle from dichlorodimethylsilane and a pyridoxalimine Schiff base ligand
Acta Crystallographica Section E: Crystallographic Communications, 2021 The reaction of dichlorodimethylsilane with a polydentate Schiff base ligand derived from pyridoxal and 2-ethanolamine yielded the macrocyclic silicon compound (8E,22E)-4,4,12,18,18,26-hexamethyl-3,5,17,19-tetraoxa-8,13,22,27-tetraaza-4,18-disilatricyclo[
Uwe Böhme +2 more
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Oxidative Carbocation Formation in Macrocycles: Synthesis of the Neopeltolide Macrocycle [PDF]
Angewandte Chemie, 2009 AbstractMakrocyclische Oxocarbeniumionen wurden aus Makrolactonen mit Benzyl‐ oder Allyletherfunktionen durch oxidative C‐H‐Bindungsaktivierung in Gegenwart von 2,3‐Dichlor‐4,5‐dicyanchinon (DDQ) erhalten. Die Nützlichkeit dieser effizienten Reaktion für die Synthese komplexer Moleküle wurde anhand ihrer Verwendung zum Aufbau des Tetrahydropyronrings ...
Wangyang, Tu, Paul E, Floreancig
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Acta Chimica Slovenica, 2017 With the application of a double dienophile 1,1'-(hexane-1,6-diyl)bis(1H-pyrrole-2,5-dione) for a [4+2] cycloaddition with a substituted 2H-pyran-2-one a novel 26-membered tetraaza heteromacrocyclic system 3 was prepared via a direct method under solvent-
Bor Lucijan Turek +3 more
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A Convergent Synthesis of the Macrocyclic Core of Cytotrienins: Application of RCM for Macrocyclization [PDF]
Organic Letters, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Evano, Gwilherm, Schaus, JV, Panek, JS
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Investigation of Structural Mimetics of Natural Phosphate Ion Binding Motifs
Molecules, 2015 Phosphates are ubiquitous in biology and nearly half of all proteins interact with their partners by means of recognition of phosphate residues. Therefore, a better understanding of the phosphate ion binding by peptidic structures is highly desirable ...
Evgeny A. Kataev, Tatiana A. Shumilova
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Molecules, 2022 The NIS synthetase family of enzymes responsible for the biosynthesis of siderophores is increasingly associated with bacterial virulence. Proteins in this class represent outstanding potential drug targets, assuming that basic biochemical and structural
Katherine M. Hoffmann +5 more
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Synthesis of Highly Functionalized Macrocycles by the Peripheral Functionalization of Macrocyclic Diimines [PDF]
The Journal of Organic Chemistry, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Miguel A, Sierra +4 more
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Heterocyclic Communications, 2019 Novel magnesium(II) porphyrazine with peripheral methyl(3,5-dibromophenylmethyl)amine groups was synthesized in a multi-step procedure starting from commercially available diaminomaleonitrile. All intermediates and the final macrocycle were characterized
Wieczorek Ewelina +5 more
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Five-component, one-pot synthesis of an electroactive rotaxane comprising a bisferrocene macrocycle
Beilstein Journal of Organic Chemistry, 2020 The templated clipping of a ferrocene-grafted isophthalic acid derivative to encircle a hydrogen-bonding axle through the reaction with 1,4-bis(aminomethyl)benzene is described.
Natalie Lagesse +6 more
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Macrocyclic Inhibitors of Hsp90 [PDF]
Current Topics in Medicinal Chemistry, 2010 Heat shock proteins (HSP) are a family of highly conserved proteins, whose expression increases in response to stresses that may threaten cell survival. Over the past decade, heat shock protein 90 (Hsp90) has emerged as a potential therapeutic target for cancer as it plays a vital role in normal cell maturation and acts as a molecular chaperone for ...
Johnson, V +4 more
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