Results 211 to 220 of about 21,344 (285)

Sex differences in dynamic cerebral autoregulation responses to resistance and endurance training in humans

Experimental Physiology, EarlyView.
Abstract Exercise maintains brain health and reduces the risk of cerebrovascular diseases, such as stroke and dementia. The benefits of different ‘modalities’ of exercise on male and female cerebral autoregulation are unclear. In this study, we compared adaptations in dynamic cerebral autoregulation (dCA) during spontaneous and forced oscillations in ...
Hannah J. Thomas, Channa E. Marsh, Leanne Lester, Louise H. Naylor, Kurt J. Smith, Daniel J. Green   +5 more
wiley   +1 more source

Exploring the macrocyclic chemical space for heuristic drug design with deep learning models. [PDF]

Commun Chem
Hu F, Jia X, Liao W, Chen Z, Bi H, Ge H, Liu D, Zhang R, Hu Y, Mei W, Zhao Z, Zhang K, Zhu L, Diao Y, Li H.   +14 more
europepmc   +1 more source

Mechanisms of haemoglobin mass expansion following heat stress

The Journal of Physiology, EarlyView.
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins, Brittany A. Edgett, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +4 more
wiley   +1 more source

Cone <i>p</i>-aminocalix[4]arenes enriched with 'clickable' alkyne or azide functionalities. [PDF]

Beilstein J Org Chem
Korniltsev I, Bazhenov V, Gorbunov A, Cheshkov D, Bezzubov S, Kovalev V, Vatsouro I.   +6 more
europepmc   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

Synthesis of Conjugated Linear and Cyclic Polyynes by Selective Alkyne Metathesis. [PDF]

Angew Chem Int Ed Engl
Escudero J, Long J, Bouëtard D, Morvan J, Koohgard M, Neitzel A, Bockfeld D, Nwachukwu S, Roisnel T, Tykwinski RR, Tamm M, Mauduit M, Trolez Y.   +12 more
europepmc   +1 more source

Cyclic Thiosulfinates: Synthesis and Applications in Chemical Biology and Materials Science

ChemBioChem, Volume 27, Issue 16, 27 August 2026.
Cyclic thiosulfinates (CTs) are strained organosulfur heterocyclic compounds with a polarized ─S(═O)─S─ bond that enables selective thiol reactivity. Advances in synthesis afford tunable scaffolds that support efficient proximal thiol cross‐linking and enable applications in chemical biology and materials science. Cyclic thiosulfinates (CTs) constitute
Benjamin Liebson, Jeffrey N. Agar, Roman Manetsch, Prakash T. Parvatkar   +3 more
wiley   +1 more source

Supramolecular Control of Dual Emission in Macrocycle-Confined Dimers. [PDF]

JACS Au
Yang T, Jones JF, Zhang S, Li B, Li S, Yu Y, Sun Y, Liu H, Yang B, Oliver TAA, Wu G.   +10 more
europepmc   +1 more source

Mechanically Interlocked Indigo Photoswitches

Angewandte Chemie, Volume 138, Issue 34, 17 August 2026.
By incorporating indigo photoswitches into the axle of a rotaxane, which features a hydrogen bonding macrocycle, we demonstrate improvement in activation wavelength, photostationary states and thermal reversion, an effect that is governed by topologically constrained supramolecular interactions.
Alexander M. Wilmshurst, Taegeun Jo, Rebecca L. Kerridge, Akanksha Ashok Sangolkar, Zhihao Ling, Alex Buchanan, Neil Wells, Yael Ben‐Tal, Stefano Crespi, George T. Williams   +9 more
wiley   +1 more source

Synthesis of the Proposed Structure of Celacarfurine and Analogues Using Sequential Cascade Ring Expansion Reactions. [PDF]

Org Lett
Tam JKF, Waddell LJN, Palate KY, Whitwood AC, Longcake A, Probert MR, Grogan G, Lichman BR, Unsworth WP.   +8 more
europepmc   +1 more source