Results 121 to 130 of about 6,769 (240)
Competing Charge Transport Pathways: A Spirobifluorene‐Based Molecular Loop
European Journal of Organic Chemistry, EarlyView.A rigid molecular loop integrating a spirobifluorene (SBF) core with a cycloparaphenylene (CPP) moiety provides two distinct transport channels. Through‐space spiroconjugation and radial π‐conjugation along a CPP backbone coexist within a single molecule.
Brian Ogi +4 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Smart Molecules, EarlyView.Herein, we constructed a series of fully B‐doped, fully N‐doped and hybrid B/N‐doped conjugated macrocycles considering three key topological factors. At a fixed ring size, the spectra initially redshift then blueshift with varying B/N ratio, while ring size exhibits negligible impact on spectra.
Wen‐Yu Guo +4 more
wiley +1 more source
Lanthanide and transition metal complexes of nitrogen and oxygen donor macrocyclic ligands [PDF]
, 1994 This thesis is concerned with the synthesis and characterisation of altogether twenty 18- and 24-membered macrocyclic ligands, incorporating the pyridyl and phenolic substituents in the cavity, coupled with their lanthanide and transition metal complexes.
Evagorou, Evagoras George
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Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
British Journal of Pharmacology, EarlyView.Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Journal of Fish Diseases, EarlyView.ABSTRACT Apteronotus albifrons (Gymnotiformes: Apteronotidae), commonly known as the black ghost knifefish, is a high‐value ornamental fish that is susceptible to various parasites. The affected fish were wild‐caught fisheries and subsequently introduced into a commercial breeding system.
Pedro Henrique Magalhães Cardoso +6 more
wiley +1 more source
Application of Organic Macrocyclic Supramolecular Structures on Adsorption and Conversion of Carbon Dioxide [PDF]
, 2010 Adsorption and conversion of carbon dioxide has called worldwide attention not only due to the increasing environmental concerns, but also in view of the carbon resource utilization.
Liu Li, Li Peipei
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Supramolecular Host‐Guest Complexation Dynamics by Cost‐Efficient Electronic Structure Methods
Chemistry – A European Journal, Volume 32, Issue 29, 7 August 2026.We present a cost‐effective multilevel workflow for the kinetic profiling of host–guest systems, illustrated with cucurbit[6]uril and alkylammonium cations. The method combines rapid docking and reaction path searches at the semi‐empirical level, with refinement of the results using modern density functional theory, accurately reproducing experiment ...
Thomas Gasevic +6 more
wiley +1 more source
Macrocyclic receptors for transmembrane transport [PDF]
, 2019 Synthetic receptors can be used to carry ions across membranes. Such carriers extract the anion from the aqueous phase, move it across the apolar interior of the lipid bilayer, to then release it on the other side of the membrane. They have potential for
Valkenier, Hennie
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C-H Activation (gamma-deprotonation) of a Sm(III) bis(trimethylsilyl)amide complex via macrocyclic stabilisation of the sodium counter ion [PDF]
, 2005 The γ-deprotonation of a samarium(III) bis(trimethylsilyl)amide complex derived from a dimetallated trans-dioxaporphyrinogen has been achieved through stabilisation of the counter cation within the macrocyclic cavity.
Michael Gardiner (14737189) +1 more
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