Results 91 to 100 of about 113,437 (249)
Medical and Veterinary Entomology, EarlyView.Attractive toxic sugar bait containing ivermectin (ATSB‐IVM) ingestion markedly reduced blood feeding, survival, oviposition, egg production and larval hatching, with the strongest effects when baits were ingested before blood feeding. Timing of ingestion (48–96 h before or after blood feeding) shaped sublethal impacts across the first and second ...
Thais Alves de Moura +2 more
wiley +1 more source
Treatment and control of bovine hypodermosis with ivermectin long-acting injection (IVOMEC® GOLD) [PDF]
, 2016 Background: The studies reported here were conducted to assess the efficacy of ivermectin long-acting injection (IVM LAI; IVOMEC® GOLD, Merial; 3.15 % w/v ivermectin) for the treatment and control of natural infestations of cattle by Hypoderma bovis and ...
Domenico Otranto +5 more
core +1 more source
Phytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.This PROSPERO‐registered review analysed 37 RCTs on neuronutraceuticals for Alzheimer's disease. Despite diverse targets—amyloid/tau, inflammation, oxidative stress, metabolism, synaptic plasticity, cholinergic and hormonal—the evidence was of low quality. RoB2 flagged attrition (86.5%) and reporting bias (81%). Current data do not support clinical use;
Mehmet Akif Topcuoglu, Esen Saka
wiley +1 more source
Inversion of the anomeric configuration of the transferred sugar during inactivation of the macrolide antibiotic oleandomycin catalyzed by a macrolide glycosyltransferase [PDF]
, 1934 Macrolides are a group of antibiotics structurally characterized by a macrocyclic lactone to which one or several deoxy-sugar moieties are attached. The sugar moieties are transferred to the different aglycones by glycosyltransferases (GTF). The OleI GTF
Quirós, Luis M. +2 more
core +2 more sources
Ring Formation in Sesquiterpene Synthesis: Biomimetic vs. Non‐Biomimetic Strategies
European Journal of Organic Chemistry, Volume 29, Issue 5, 7 February 2026.A short review of cyclase enzyme‐mediated ring formation in sesquiterpene biosynthesis is presented as a prelude to six case studies examining the merits and demerits of biomimetic vs. non‐biomimetic strategies for carbocyclisation in the total synthesis of this iconic natural product class.
Bohan Lin, Chen Dai, Alan C. Spivey
wiley +1 more source
Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
Advanced Functional Materials, Volume 36, Issue 16, 23 February 2026.This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source
FIVE REASONS TO PRESCRIBE A MACROLIDE FOR ENT DISEASE
Медицинский совет, 2016 Macrolides are antibiotics the chemical structure of which has a macrocyclic lactone ring. Macrolides have several advantages over other groups of antibiotics. They are characterized by high antibacterial activity against intracellular pathogens and have
V. V. SHILENKOVA
doaj +1 more source
The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery [PDF]
, 2013 <p>Background: The small ruminant parasite Haemonchus contortus is the most widely used parasitic nematode in drug discovery, vaccine development and anthelmintic resistance research.
Adam J Reid +26 more
core +3 more sources
Health Science Reports, Volume 9, Issue 2, February 2026.ABSTRACT Background and Aims Acne vulgaris is a frequent skin disorder, affecting a large part of the population worldwide, and strongly influencing not only the physical but also the mental aspects of health. The choice of therapy for acne vulgaris is a very difficult one because the multifactorial causality of the disease and interindividual ...
Mobina Tajdari +5 more
wiley +1 more source
Macrocyclization Reactions: The Importance of Conformational, Configurational, and Template-Induced Preorganization [PDF]
, 2015 The success of a given macrocyclization reaction involves a very delicate balance of many different factors. First, a proper understanding of the basic thermodynamic and kinetic concepts underlying these processes is essential in defining the strategies ...
Burguete, M. Isabel +3 more
core +2 more sources