Results 31 to 40 of about 8,305 (169)

The Ivermectin Related Compound Moxidectin Can Target Apicomplexan Importin α and Limit Growth of Malarial Parasites

Cells
Signal-dependent transport into and out of the nucleus mediated by members of the importin (IMP) superfamily is crucial for eukaryotic function, with inhibitors targeting IMPα being of key interest as anti-infectious agents, including against the ...
Sujata B. Walunj, Geetanjali Mishra, Kylie M. Wagstaff, Swati Patankar, David A. Jans   +4 more
doaj   +1 more source

Investigating management choices for canine heartworm disease in northern Mississippi

Parasites & Vectors, 2017
Background There are concerns that the chronic use of macrocyclic lactone preventives to kill adult heartworms (“soft-” or “slow-kill”) may have contributed to the development of macrocyclic lactone resistance.
Tobi N. Ku
doaj   +1 more source

12-Hydroxycorniculatolide a from the Mangrove Tree,

Natural Product Communications, 2018
A new macrocyclic lactone, 12-hydroxycorniculatolide A ( 1 ), along with three known compounds, corniculatolide A ( 2 ), 12-hydroxy-11- O -methyl-corniculatolide A ( 3 ) and 6,7-dimethoxycoumarin ( 4 ) were isolated from the methanolic extract of the ...
Puttandon Wongsomboon, Wisanu Maneerat, Stephen G Pyne, Luksamee Vittaya, Thunwadee Limtharakul(née Ritthiwigrom)   +4 more
doaj   +1 more source

Water, Alcohols, Amines, and Amides as Formal Hydrogen‐Atom‐Transfer Reagents Through Activation With Redox‐Active Lewis Acids

Angewandte Chemie International Edition, EarlyView.
Protic molecules containing strong O─H or N─H bonds typically resist hydrogen‐atom abstraction because of the high reactivity of the resulting heteroatom‐centered radicals. However, association of the protic molecules with redox‐active Lewis acids can provide powerful hydrogen‐atom donors or proton‐coupled‐electron‐transfer reagents.
Petra Vojáčková, Armido Studer
wiley   +1 more source

Kallolide A acetate pyrazoline

Acta Crystallographica Section E, 2012
In the crystal structure of kallolide A acetate pyrazoline [systematic name: 7-methyl-16-oxo-4,10-bis(prop-1-en-2-yl)-17,18-dioxa-14,15-diazatetracyclo[9.4.2.16,9.01,12]octadeca-6,8,14-trien-5-yl acetate], C23H28N2O5, there is a 12-membered carbon ...
Idaliz Rodríguez-Escudero, Jeffrey Marrero, Abimael D. Rodríguez   +2 more
doaj   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Parascaris spp. induced surgical colic in juvenile horses—A Scandinavian perspective

Equine Veterinary Journal, EarlyView.
Abstract Background Parascaris spp. commonly infects foals, and high burdens can cause fatal small intestinal impactions. Progressive anthelmintic resistance poses a risk for an increase of Parascaris spp. related disease in juvenile horses. Objectives To investigate Parascaris‐related surgical intestinal lesions, with special emphasis on ascarid ...
E. Tydén, I. R. Hellings, K. Toft Nielsen, A. Bergren, I. Holmgren, S. Attin, T. Pihl, A. Kendall, Y. Hedberg Alm   +8 more
wiley   +1 more source

Heartworms, macrocyclic lactones, and the specter of resistance to prevention in the United States

Parasites & Vectors, 2012
In order to provide a background to current concerns relative to the possible resistance of heartworms to macrocyclic lactones, this review summarizes various studies in which lack of efficacies (LOEs) have been observed in dogs on macrocyclic lactone ...
Bowman Dwight D
doaj   +1 more source

Dynamic Polydisulfide Latex via Emulsion Ring‐Opening Polymerization of Cyclodisulfides

Journal of Polymer Science, EarlyView.
A polydisulfide latex with a high molar mass was achieved by emulsion polymerization process starting from a dithiol. The mechanism reveals an entropy‐driven ring‐opening polymerization involving disulfide macrocycle intermediates. The polydisulfide particles can be degraded by thiol‐disulfide exchange, and the disulfide fragments can be reengaged in a
Sandric Afonso, Pierre‐Louis Quentin, Marc Schmutz, Cécile Joyeux, Cuong Minh Quoc Le, Abraham Chemtob   +5 more
wiley   +1 more source

Pesticide use in integrated pest and pollinator management framework to protect pollinator health

Pest Management Science, Volume 81, Issue 4, Page 1691-1696, April 2025.
Integrated pest management (IPM) emphasizes non‐chemical methods, with pesticides as a last resort, while integrated pest and pollinator management (IPPM) integrates pollinator health into pest control strategies. Abstract Agricultural pesticides have historically been a critical tool in controlling pests and diseases, preventing widespread suffering ...
Ngoc T Phan, David J Biddinger, Edwin G Rajotte, Guy Smagghe, Gadi VP Reddy, Zong‐Xin Ren, Neelendra K Joshi   +6 more
wiley   +1 more source