Results 11 to 20 of about 8,305 (169)
First case of macrocyclic lactone-resistant Dirofilaria immitis in Europe - Cause for concern [PDF]
International Journal for Parasitology: Drugs and Drug ResistanceHeartworm disease caused by the nematode Dirofilaria immitis is one of the most important parasitoses of dogs. The treatment of the infection is long, complicated, risky and expensive.
Donato Traversa +8 more
doaj +2 more sources
Preventive efficacy of oral moxidectin at various doses and dosage regimens against macrocyclic lactone-resistant heartworm (Dirofilaria immitis) strains in dogs [PDF]
Parasites & Vectors, 2019 Background Moxidectin has previously shown limited efficacy (≤ 44.4%) against confirmed macrocyclic lactone (ML)-resistant Dirofilaria immitis strains at 3 µg/kg after single and multiple oral dosages. Three studies were conducted to evaluate higher oral
Tom L. McTier +7 more
doaj +2 more sources
Animals, 2022 Dirofilaria immitis is a zoonotic parasitic nematode that infects domestic and wild canids, among its vertebrate hosts. The genetic analysis of D. immitis nowadays transcends the need for genetic taxonomy of nematodes, such as the study of resistance to ...
Sónia Gomes-de-Sá +7 more
doaj +1 more source
Diagnosis and control of anthelmintic-resistant
Parasites & Vectors, 2009 Since 2002, macrocyclic lactone resistance has been reported in populations of Parascaris equorum from several countries. It is apparent that macrocyclic lactone resistance developed in response to exclusive and/or excessively frequent use of ivermectin ...
Reinemeyer Craig R
doaj +1 more source
Olefinic-Lactone Cyclizations to Macrocycles [PDF]
Organic Letters, 2008 Olefinic-lactone cyclization reactions that result in the generation of macrocycles are described.
John C, Rohanna, Jon D, Rainier
openaire +2 more sources
Resistance against macrocyclic lactones in Psoroptes ovis in cattle
Parasites & Vectors, 2020 Background Psoroptic mange is an important disease in Belgian Blue cattle. Treatment failure of macrocyclic lactones against Psoroptes ovis has been reported, but clear evidence of in vivo resistance is lacking.
Wouter van Mol +6 more
doaj +1 more source
Selamectin Is the Avermectin with the Best Potential for Buruli Ulcer Treatment. [PDF]
PLoS Neglected Tropical Diseases, 2015 A comprehensive analysis was done to evaluate the potential use of anti-parasitic macrocyclic lactones (including avermectins and milbemycins) for Buruli ulcer (BU) therapy.
Nicole Scherr +3 more
doaj +1 more source
Recording drug responses from adult Dirofilaria immitis pharyngeal and somatic muscle cells
International Journal for Parasitology: Drugs and Drug Resistance, 2021 Despite being considered one of the most pathogenic helminth infections of companion animals, members of macrocyclic lactone class are the only drugs available for the prevention of heartworm disease caused by Dirofilaria immitis.
S. Verma +4 more
doaj +1 more source
Synthesis of Macrocyclic Lactones
Journal of Japan Oil Chemists' Society, 1970 Erucic acid (I) as starting material has been used to synthesize 1, 14-tetradecanolide in the macrocyclic lactones, which has practical value as musk like odor.Erucyl bromide (IV) was synthesized by reduction of ethyl erucinonate (II) into erucyl alcohol (III) followed by bromination.As method (a), prepared the nitrile by usual method, and nitrile was ...
Hiromu KAMEOKA +3 more
openaire +3 more sources
Ветеринария сегодня, 2019 Multiple researches demonstrate that both invasive diseases and use of anthelmintcs adversely affect horse immunity harming the gut flora. Macrocyclic lactone anthelmintics are proved to be highly effective agents but there is insufficient knowledge of ...
О. A. Mullagaliyeva, Ye. N. Zakrepina
doaj +1 more source