Results 51 to 60 of about 113,437 (249)
Ivermectin - old drug, new tricks? [PDF]
, 2017 Ivermectin is one of the most important drugs in veterinary and human medicine for the control of parasitic infection and was the joint focus of the 2015 Nobel Prize in Physiology or Medicine, some 35 years after its remarkable discovery.
Devaney, Eileen +2 more
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Arquivo Brasileiro de Medicina Veterinária e ZootecniaThe present study aimed to identify the climate condition parameters that are associated with the occurrence of antimicrobial and macrocyclic lactone residues in bulk tank milk using a multivariate principal components analysis (PCA).
L.C.A. Picinin +10 more
doaj +1 more source
Investigating management choices for canine heartworm disease in northern Mississippi
Parasites & Vectors, 2017 Background There are concerns that the chronic use of macrocyclic lactone preventives to kill adult heartworms (“soft-” or “slow-kill”) may have contributed to the development of macrocyclic lactone resistance.
Tobi N. Ku
doaj +1 more source
Treatment strategies for sheep scab:an economic model of farmer behaviour [PDF]
, 2017 Ovine psoroptic mange (sheep scab) is a debilitating and damaging condition caused by a hypersensitivity reaction to the faecal material of the parasitic mite Psoroptes ovis. Farmers incur costs from the use of prophylactic acaricides and, if their sheep
Nixon, Emily +2 more
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CellsSignal-dependent transport into and out of the nucleus mediated by members of the importin (IMP) superfamily is crucial for eukaryotic function, with inhibitors targeting IMPα being of key interest as anti-infectious agents, including against the ...
Sujata B. Walunj +4 more
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Kallolide A acetate pyrazoline
Acta Crystallographica Section E, 2012 In the crystal structure of kallolide A acetate pyrazoline [systematic name: 7-methyl-16-oxo-4,10-bis(prop-1-en-2-yl)-17,18-dioxa-14,15-diazatetracyclo[9.4.2.16,9.01,12]octadeca-6,8,14-trien-5-yl acetate], C23H28N2O5, there is a 12-membered carbon ...
Idaliz Rodríguez-Escudero +2 more
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Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B12) [PDF]
, 2013 It has been known for the past 20 years that two pathways exist in nature for the de novo biosynthesis of the coenzyme form of vitamin B12, adenosylcobalamin, representing aerobic and anaerobic routes.
Biedendieck, Rebekka +7 more
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Heartworms, macrocyclic lactones, and the specter of resistance to prevention in the United States
Parasites & Vectors, 2012 In order to provide a background to current concerns relative to the possible resistance of heartworms to macrocyclic lactones, this review summarizes various studies in which lack of efficacies (LOEs) have been observed in dogs on macrocyclic lactone ...
Bowman Dwight D
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Incidence of anthelmintic resistance in cattle farms in Northern Germany – first results [PDF]
, 2008 Anthelmintic resistance (AR) is an increasing problem worldwide especially for small ruminants and it is also rising in cattle. To maintain the efficacy of anthelmintics is an important objective.
Demeler, J. +3 more
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Chemoenzymatic and Template-Directed Synthesis of Bioactive Macrocyclic Peptides [PDF]
, 2005 Nonribosomal peptide synthetases (NRPS) are large multienzyme complexes, which simultaneously represent template and biosynthetic machinery for the production of structurally diverse peptidic products that feature high pharmacological and biological ...
Grünewald, Jan +1 more
core +1 more source