Results 111 to 120 of about 442 (127)
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Synthesis of dimeric and tetrameric macrolactams with cytotoxic activity

2000
Cyclization of amino acid prepd. from 4,4-dimethylcyclohex-2-en-1-one by std. chem., yielded the dimeric and tetrameric macrolactams (I) and (II), resp., representing the first examples of "taxoid-like" compds. with heterocyclic B rings. I and II exhibited moderate antiproliferative activity in an in vitro cytotoxicity assay.
Gentile, Gabriella   +5 more
openaire   +2 more sources

Neat synthesis of c-fused pyrroles and its application to macrolactamization

Synthetic Communications, 2021
Anirban Bera, Sk Asraf Ali, Amit Saha
exaly  

Macrolactams: a new class of antifungal agents

Journal of the American Chemical Society, 1990
Vinod R. Hegde   +6 more
openaire   +1 more source

Total Synthesis of the Antitumor Depsipeptide FE399 and Its S‐Benzyl Derivative: A Macrolactamization Approach

European Journal of Organic Chemistry, 2020
Takayuki Tonoi   +2 more
exaly  

Macrolactamization Approaches to Arylomycin Antibiotics Core

Organic Letters, 2019
Ngiap-Kie Lim   +2 more
exaly  

A formal synthesis of FK-506. Exploration of some alternatives to macrolactamization

Journal of Organic Chemistry, 1990
Samuel J Danishefsky
exaly  

A New Cyclase Family Catalyzing Head-to-Tail Macrolactamization of Non-ribosomal Peptides

Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 2019
Kenichi Matsuda   +2 more
exaly  

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