Results 131 to 140 of about 56,953 (293)

Australian consensus recommendations for the management of increased meningococcal infection risk in adults with neurological diseases treated with complement inhibitors

Internal Medicine Journal, EarlyView.
Abstract Complement inhibitor therapy carries a risk of serious infections, including meningococcal disease. Here we provide evidence‐based recommendations and expert consensus for immunisation and prophylactic treatment of patients receiving, or planning to receive, complement inhibitors for neurological conditions in the Australian setting.
Katherine A. Buzzard, Michael Barnett, Heidi Beadnall, Mirasol Forcadela, Lesley‐Ann Hall, Victoria G. Hall, Todd Hardy, Danny Hsu, Paul Kinsella, Mastura Monif, Sudarshini Ramanathan, Stephen W. Reddel, Sean Riminton, Douglas F. Johnson   +13 more
wiley   +1 more source

NDMA in macrolides

N-nitrosodimethylamine (NDMA) is the most commonly found N-nitrosamine in pharmaceutical drug substances (DSs) and drug products. This paper investigates the potential of macrolide antibiotics, containing dimethylamino group, as precursors for NDMA ...
Grahek, Rok, Roškar, Robert, Golob, Nejc   +2 more
core   +1 more source

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

Journal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura, Ayana Tatsuno, Yamato Noto, Ryosuke Wakamatsu, Masayuki Sakunami, Ryu Kobayashi, Miki Yamashita   +6 more
wiley   +1 more source

Isolation and Identification of Erysipelothrix sp. in Hybrid Grouper (Epinephelus fuscoguttatus × E. lanceolatus) in Taiwan

Journal of Fish Diseases, EarlyView.
ABSTRACT In February 2025, a mortality event of unknown aetiology occurred at a hybrid grouper (Epinephelus fuscoguttatus × Epinephelus lanceolatus) aquaculture farm in southern Taiwan, with sporadic daily deaths persisting for a month. Four moribund groupers were collected over three sampling intervals for diagnostic investigation.
Shang‐Ting Wu, Yu‐Siang Lin, Chia‐Yu Hsieh   +2 more
wiley   +1 more source

Type IV‐Dominated Plasmid‐Encoded CRISPR‐Cas Systems Are Enriched in Multireplicon and Multi‐Stressor Resistance Plasmids Across the Global Plasmidome

Molecular Microbiology, EarlyView.
Screening 72,555 plasmid sequences reveals that intact CRISPR‐Cas systems are rare (1.03%) but strongly enriched in multireplicon and multi‐stressor resistance plasmids, with Type IV‐A as the dominant subtype. These findings implicate plasmid‐encoded CRISPR‐Cas as non‐randomly retained elements of structurally complex and high‐risk backbones.
Hannay Crystynah Almeida de Souza, Anamaria Mota Pereira dos Santos, Arlen Carvalho de Oliveira Almeida, Carlos Adam Conte Junior, Pedro Panzenhagen   +4 more
wiley   +1 more source

Urban ants as potential mechanical vectors of pathogenic and antibiotic‐resistant bacteria in a Brazilian hospital

Medical and Veterinary Entomology, EarlyView.
Nine ant taxa were identified in a Brazilian hospital, with Tapinoma melanocephalum and Dorymyrmex brunneus being the most abundant. Eighty‐five percent of collected ants yielded detectable bacterial growth, including clinically relevant genera such as Acinetobacter, Pseudomonas, Escherichia coli and Pluralibacter.
Luana Biggi Souza, Anny Karoliny de Lima Dionisio, Mayara Acioli Cedrim, Luiz Carlos Silva Dias Neto, Ellymaira Freitas Pontes, Yáskara Veruska Ribeiro Barros, Renato Júnior Cavalcante da Silva, Ênio Jose Bassi, Jacques Hubert Charles Delabie, Ana Lucia Biggi Souza, Leticia Anderson   +10 more
wiley   +1 more source

Pharmacogenomics in Dentistry: From CYP‐Mediated Drug Response to Precision Prescribing in Oral Healthcare

Oral Diseases, EarlyView.
ABSTRACT Objective This narrative review critically assesses the clinical relevance of pharmacogenomics within dental genomics, distinguishing clinically actionable applications from emerging or investigational findings. Materials and Methods A targeted literature review was conducted in PubMed/MEDLINE, Scopus and Embase for publications from January ...
Giorgia Pieretto, Jessica Cusato, Martina Sansavini, Christian Bacci   +3 more
wiley   +1 more source

Corrigendum: Functional Repertoire of Antibiotic Resistance Genes in Antibiotic Manufacturing Effluents and Receiving Freshwater Sediments

Frontiers in Microbiology, 2018
Juan J. González-Plaza, Ana Šimatović, Milena Milaković, Ana Bielen, Fabienne Wichmann, Nikolina Udiković-Kolić   +5 more
doaj   +1 more source

Corrigendum: Antibiotic susceptibility pattern of Portuguese environmental Legionella isolates

Frontiers in Cellular and Infection Microbiology, 2023
Carolina Cruz, Lúcia Rodrigues, Filipa Fernandes, Ricardo Santos, Paulo Paixão, Maria Jesus Chasqueira   +5 more
doaj   +1 more source

GROUP B AND G BETA-HEMOLYTIC STREPTOCOCCI IN POMURJE REGION – CHARACTERISTICS OF ANTIMICROBIAL RESISTANT ISOLATES

Zdravniški Vestnik, 2003
Background. Macrolide-resistant strains of betahemolytic streptococci have been isolated in Pomurje region in Slovenia. The aim of the study was to determine phenotypes of macrolide-lincozamide resistance and patterns of resistance to selected ...
Iztok Štrumbelj, Katja Seme
doaj