Results 111 to 120 of about 56,953 (293)

Spatial Patterns and Associated Factors of Intestinal Antibiotic Resistance Genes in Farmed Bullfrogs From Selected Farms Across Major Production Regions in China

Integrative Zoology, EarlyView.
Across selected bullfrog farms in major Chinese production regions, 106 intestinal ARG subtypes were detected, with tetracycline and sulfonamide resistance genes predominating and clear farm‐level variation. High‐risk ARGs, including ermB, floR, and qnrA, were associated with heavy metals, MGEs, and opportunistic pathogens. These findings highlight the
Yang Xu, Rui Chen, Qiang Wei, Zhiming Liu, Jianguo Xiang, Deliang Li, Junhua Li, Xinhua Liu   +7 more
wiley   +1 more source

Marine Macrolides with Antibacterial and/or Antifungal Activity

, 2019
Currently, the increasing resistance of microorganisms to antibiotics is a serious problem. Marine organisms are the source of thousands of substances, which also have antibacterial and antifungal effects.
Tomasz M. Karpiński, Tomasz M. Karpiński   +1 more
core   +1 more source

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

Allergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud, Lene Heise Garvey, Elizabeth Phillips, Michael Ardern‐Jones, Sevim Bavbek, Patrizia Bonadonna, Jean‐Christoph Caubet, Ana‐Maria Copaescu, Valentina Gueli, Jose Julio Laguna, Ricardo Madrigal‐Burgaleta, Francesca Mori, Vito Sabato, Maria J Torres, Knut Brockow   +14 more
wiley   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Increased susceptibility of Pseudomonas aeruginosa to macrolides and ketolides in eukaryotic cell culture media and biological fluids due to decreased expression of oprM and increased outer-membrane permeability.

, 2012
Macrolides show antimicrobial activity against P. aeruginosa in eukaryotic media through increased uptake and reduced efflux.
Traore, H, Vanderbist, F, Van Bambeke, Françoise, Buyck, Julien, Buyck, Julien M, Vanderbist, F., Plésiat, Patrick, Traore, H., Tulkens, Paul M., Tulkens, Paul   +9 more
core   +1 more source

Efficacy and safety of topical macrolides versus systemic tetracyclines for meibomian gland dysfunction–a systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract Purpose To review the efficacy and safety of oral doxycycline antibiotics versus topical macrolides in the treatment of meibomian gland dysfunction (MGD). Design Systematic review and meta‐analysis. Methods A comprehensive search of PubMed, Scopus, Embase, and ClinicalTrials.gov through December 2024 identified randomised controlled trials ...
Margarita Safir, Clara C. Chan, Joshua C. Teichman, Itamar Arbel, Ruth Lapid‐Gortzak, Camiel J. F. Boon, Michael Mimouni, Dror Ben Ephraim Noyman   +7 more
wiley   +1 more source

Macrolides in the treatment of community-acquired infections of lower respiratory tract

, 2013
Infections of the lower respiratory tract are a serious challenge for modern healthcare. Macrolides occupy a special place in the list of antibiotics recommended for the treatment of such conditions, which is not only due to their high safety and ...
A. V. Golub, R. S. Kozlov
core   +1 more source

Antimicrobial Resistance in Children With Bloodstream Infections: A Population‐Based Study in Stockholm, Sweden

Acta Paediatrica, EarlyView.
ABSTRACT Aim We retrospectively evaluated trends in antimicrobial resistance (AMR) in paediatric bloodstream infections and assessed changes in antimicrobial prescription patterns over a 20‐year period. Methods We analysed positive blood cultures from children admitted with suspected serious infection between 1998 and 2018.
Joachim Luthander, Rutger Bennet, Per Nydert, Margareta Eriksson, Christian G. Giske, Anna Nilsson   +5 more
wiley   +1 more source

Lobatamides A and B, Novel Cytotoxic Macrolides from the Tunicate Aplidium lobatum^†

, 2016
Lobatamides A and B, Novel Cytotoxic Macrolides from the Tunicate Aplidium lobatum†
Lewis K. Pannell (2280364), Deborah L. Galinis (3042441), John H. Cardellina (2085223), Michael R. Boyd (2709340), Tawnya C. McKee (2039704)   +4 more
core   +1 more source

A Real‐World Controlled Multicentre Study Evaluating the Association Between Benralizumab Therapy and Major Outcomes in Severe Asthma

Clinical &Experimental Allergy, EarlyView.
Among patients with severe eosinophilic asthma, benralizumab was associated with greater improvements in asthma outcomes—such as improved asthma control, quality of life and remission rates—compared to biologic‐naïve patients. ABSTRACT Background Real‐world data on benralizumab in patients with severe eosinophilic asthma–while controlling for ...
Dennis Thomas, Vanessa M. McDonald, Gijo Thomas, Joy Lee, Li Ping Chung, Matthew Peters, Shakti D. Shukla, Yuto Hamada, Erin S. Harvey, Michael Fricker, Hayley See, Rejoy Sabin Thomas, Claude S. Farah, Andrew Gillman, Constance H. Katelaris, Gregory P. Katsoulotos, David Langton, Peter G. Middleton, Paul Reynolds, Janet Rimmer, Francis Thien, Stephen Vincent, John W. Upham, Peter G. Gibson   +23 more
wiley   +1 more source