Results 101 to 110 of about 43,807 (217)

The interplay between molecular architecture, pharmacology, and suspected adverse drug reactions associated with nonsteroidal androgen antagonists in the United Kingdom

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2863-2873, August 2026.
Aims This work aimed to correlate potential links between the suspected adverse drug reaction (ADR) profile of licensed nonsteroidal androgen receptor antagonists (NSARA) with their unique chemical properties and known off‐target polypharmacology. Methods Physicochemical and polypharmacology data were curated from the Electronic Medicines Compendium ...
Simrit Dhillon   +2 more
wiley   +1 more source

Safety Profile of Sclerosing Agents in the Management of Low‐Flow Vascular Malformations of the Head and Neck—A Systematic Review

open access: yesHead &Neck, Volume 48, Issue 8, Page 2290-2305, August 2026.
ABSTRACT Background Low‐flow vascular malformations (LFVMs) of the head and neck, including venous and lymphatic malformations, represent a heterogeneous group of congenital anomalies frequently requiring intervention due to functional and esthetic impairment.
Riccardo Nocini   +6 more
wiley   +1 more source

Macrolide progress [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 1990
openaire   +2 more sources

Prevalence, Antimicrobial Resistance, and Genetic Diversity of Non‐Typeable Streptococcus pneumoniae Carriage: A Systematic Review and Meta‐Analysis

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Non‐typeable Streptococcus pneumoniae (NT‐Sp) strains lack detectable capsules and are often missed by traditional serotyping. While associated primarily with asymptomatic carriage, NT‐Sp has emerged as a key player in antimicrobial resistance (AMR) gene dissemination and serotype replacement in the post‐vaccine era. This systematic
Robert K. Reeks   +2 more
wiley   +1 more source

An Open‐Label, 2‐Period, Fixed Sequence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Single Doses of STS101 (Dihydroergotamine Nasal Powder), with and without Concomitant Itraconazole in Healthy Adult Subjects

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Dihydroergotamine (DHE) prescribing information contains a boxed warning regarding the possibility of serious and/or life‐threatening peripheral ischemia with co‐administration of strong cytochrome P450 3A4 (CYP3A4) inhibitors. The effects of the strong CYP3A4 inhibitor itraconazole on the pharmacokinetics and safety of nasally administered ...
Detlef Albrecht   +2 more
wiley   +1 more source

Cigarette Smoke‐Exposed Alveolar Epithelial Cell‐Derived Exosomes Exacerbate Skeletal Muscle Dysfunction Through HDAC2 Signalling

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Skeletal muscle dysfunction (SMD) is a common extrapulmonary complication of chronic obstructive pulmonary disease (COPD). Histone deacetylase 2 (HDAC2) is closely involved in the suppression of inflammatory transcription and is progressively reduced during COPD progression.
Chao Li   +4 more
wiley   +1 more source

Corrigendum: Functional Repertoire of Antibiotic Resistance Genes in Antibiotic Manufacturing Effluents and Receiving Freshwater Sediments

open access: yesFrontiers in Microbiology, 2018
Juan J. González-Plaza   +5 more
doaj   +1 more source

Corrigendum: Antibiotic susceptibility pattern of Portuguese environmental Legionella isolates

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Carolina Cruz   +5 more
doaj   +1 more source

GROUP B AND G BETA-HEMOLYTIC STREPTOCOCCI IN POMURJE REGION – CHARACTERISTICS OF ANTIMICROBIAL RESISTANT ISOLATES

open access: yesZdravniški Vestnik, 2003
Background. Macrolide-resistant strains of betahemolytic streptococci have been isolated in Pomurje region in Slovenia. The aim of the study was to determine phenotypes of macrolide-lincozamide resistance and patterns of resistance to selected ...
Iztok Štrumbelj, Katja Seme
doaj  

Seasonal Restructuring of Microbial Communities and Resistomes in the Shitalakshya River, Bangladesh Revealed by Shotgun Metagenomics

open access: yesMicrobiologyOpen, Volume 15, Issue 4, August 2026.
Dry‐season pollutant concentration drives microbial restructuring in Bangladesh's Shitalakshya River, shifting communities from Myroides to stress‐tolerant genera while enriching metal resistance genes and efflux pumps, revealing non‐antibiotic co‐selection as a key driver of antimicrobial resistance in urban waters.
Muhammad Ehteshamul Haque   +3 more
wiley   +1 more source

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