Results 91 to 100 of about 56,953 (293)

Manure Composting as a Strategy to Mitigate Antibiotic Resistance Dissemination in Agricultural Systems

Land Degradation &Development, EarlyView.
ABSTRACT Livestock manure is a valuable agricultural resource but may introduce antibiotic residues and antibiotic resistance genes (ARGs) into the environment. This review critically evaluates the fate of antibiotics and ARGs during manure composting and identifies the principal factors controlling their attenuation.
Magdalena Urbaniak
wiley   +1 more source

Functional Repertoire of Antibiotic Resistance Genes in Antibiotic Manufacturing Effluents and Receiving Freshwater Sediments

Frontiers in Microbiology, 2018
Environments polluted by direct discharges of effluents from antibiotic manufacturing are important reservoirs for antibiotic resistance genes (ARGs), which could potentially be transferred to human pathogens.
Juan J. González-Plaza, Ana Šimatović, Milena Milaković, Ana Bielen, Fabienne Wichmann, Nikolina Udiković-Kolić   +5 more
doaj   +1 more source

Disease Burden, Temporal Trends, and Key Influencing Factors of Lower Respiratory Infections in Asia, 1990–2023: Based on GBD 2023

Med Research, EarlyView.
In 2023, marked regional heterogeneity was observed across Asia: South Asia carried the highest incidence and prevalence, Central Asia had the highest DALY rate, Southeast Asia bore the highest mortality and East Asia and High‐income Asia‐Pacific generally had lower rates.
Lingxia Zhang, Yufeng Li, Enjun Dong, Mingming Zhang, Yuan Tian, Shuang Zhou, Ruizi Ni, Yajing An, Xiaojuan Qin, Bingrui Gao, Qi Shen, Weiguo Sun, Yanhua Liu, Wenping Gong   +13 more
wiley   +1 more source

Macrolides for KCNJ5–mutated aldosterone-producing adenoma (MAPA): design of a study for personalized diagnosis of primary aldosteronism

Blood Pressure, 2018
Purpose: Aldosterone-producing adenoma (APA) is the main curable cause of endocrine hypertension cause of primary aldosteronism (PA) and it is in up to 66% of all cases investigated with adrenal vein sampling (AVS).
Giuseppe Maiolino, Giulio Ceolotto, Michele Battistel, Giulio Barbiero, Maurizio Cesari, Laurence Amar, Brasilina Caroccia, Roberto Padrini, Michel Azizi, Gian Paolo Rossi   +9 more
doaj   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Clinical outcomes of empirical topical nifuratel or nitrofurantoin in Streptococcus pyogenes vulvovaginitis: A retrospective study

International Journal of Gynecology &Obstetrics, EarlyView.
Marek Stefan, Kristyna Krogh, Jaroslava Zikova, Marta Novackova, Marcela Krutova   +4 more
wiley   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

NEWER MACROLIDES [PDF]

Medical Journal Armed Forces India, 1996
S K, Sharma, A S, Kasthuri
openaire   +2 more sources

Microbial Culture Profiles Following Fetal Surgery Versus Spontaneous Preterm Prelabor Rupture of Membranes in Multifetal Gestations

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To assess microbial culture profiles and antibiotic resistance patterns in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) following fetal surgery compared with spontaneous PPROM without fetal surgery. Method This retrospective cross‐sectional study included women with multiple pregnancies and PPROMs < 34 ...
Ohad Houri, Kinneret Tenenbaum Gavish, Bar Narkis, Ofir Sternfeld, Yael Haring, Eran Hadar, David Danon, Ana Idelson, Nir‐Ram Duvdevani, Yuval Gielchinsky   +9 more
wiley   +1 more source