Results 111 to 120 of about 925,934 (312)

Well-Defined Conjugated Macromolecules Based on Oligo(Arylene Ethynylene)s in Sensing [PDF]

, 2020
Agata Krywko‐Cendrowska, Dawid Szweda, Róża Szweda   +2 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Macromolecules [PDF]

, 2016
Jan Schwarzbauer, Branimir Jovančićević   +1 more
openaire   +2 more sources

Preparation of pH-Responsive Tanshinone IIA-Loaded Calcium Alginate Nanoparticles and Their Anticancer Mechanisms

Pharmaceutics
Background: Tanshinone IIA (Tan IIA) is a lipophilic active constituent derived from the rhizomes and roots of Salvia miltiorrhiza Bunge (Danshen), a common Chinese medicinal herb.
Tianying Ren, Jing Wang, Yingxin Ma, Yichen Huang, Somy Yoon, Lijun Mu, Ru Li, Xuekun Wang, Lina Zhang, Pan Li, Lusha Ji   +10 more
doaj   +1 more source

Macromolecules [PDF]

Protein Science, 1994
openaire   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Effect of different concentrations of lysine on the transglutaminase-induced mixed surimi gel properties

Food Science of Animal Products
The effect of different content of lysine (Lys, 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, m/m) on the texture characteristics and water holding capacity (WHC) of transglutaminase (0.4%)-induced mixed surimi gels was explored.
Yungang Cao, Guangcan Liang, Zhaorui Li, Dongxu Du, Wenqing Ma, Xinling Dong, Li Feng, Huan Zhang, Zelong Liu   +8 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Covalently grafted human serum albumin coating mitigates the foreign body response against silicone implants in mice

Bioactive Materials
Implantable biomaterials and biosensors are integral components of modern medical systems but often encounter hindrances due to the foreign body response (FBR). Herein, we report an albumin coating strategy aimed at addressing this challenge.
Xianchi Zhou, Hongye Hao, Yifeng Chen, Wenzhong Cao, Zihao Zhu, Yanwen Ni, Zuolong Liu, Fan Jia, Youxiang Wang, Jian Ji, Peng Zhang   +10 more
doaj   +1 more source

Angiotensin converting enzyme inhibition ameliorates glomerular filtration of macromolecules and water and lessens glomerular injury in the rat. [PDF]

, 1990
Andrea Remuzzi, Stefania Puntorieri, Cristina Battaglia, Tullio Bertani, Giuseppe Remuzzi   +4 more
openalex   +1 more source