Results 1 to 10 of about 640,128 (173)
Liposomal Dexamethasone Reduces A/H1N1 Influenza-Associated Morbidity in Mice
Frontiers in Microbiology, 2022 Re-emerging viral threats have continued to challenge the medical and public health systems. It has become clear that a significant number of severe viral infection cases are due to an overreaction of the immune system, which leads to hyperinflammation ...
Jung Won Kwon +9 more
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Microbial Biotechnology, 2022 Summary Colorectal cancer pathogenesis and progression is associated with the presence of Fusobacterium nucleatum and the reduction of acetylated derivatives of spermidine, as well as dietary components such as tannin‐rich foods.
José Miguel Mancheño +23 more
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A new era of macrophage-based cell therapy
Experimental and Molecular Medicine, 2023 Macrophages are essential innate immune cells found throughout the body that have protective and pathogenic functions in many diseases. When activated, macrophages can mediate the phagocytosis of dangerous cells or materials and participate in effective ...
Yi Rang Na +2 more
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Effects of mesoporous SiO2-CaO nanospheres on the murine peritoneal macrophages -- Candida albicans interface [PDF]
Int Immunopharmacol International Immunopharmacology. 2021 Mar
20;94:107457, 2021 The use of nanoparticles for intracellular drug delivery could reduce the toxicity and side effects of the drug but, the uptake of these nanocarriers could induce adverse effects on cells and tissues after their incorporation. Macrophages play a central role in host defense and are responsible for in vivo nanoparticle trafficking.
arxiv +1 more source
Macrophage anti-inflammatory behaviour in a multiphase model of atherosclerotic plaque development [PDF]
Bull Math Biol 85, 37 (2023), 2022 Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages that form in the artery wall. The inflammation is often non-resolving, due in large part to changes in normal macrophage anti-inflammatory behaviour that are induced by the toxic plaque microenvironment ...
arxiv +1 more source
Journal of Nanobiotechnology, 2023 Background Immune checkpoint inhibitors such as anti-programmed cell death protein 1 (PD1) block tumor growth by reinvigorating the immune system; however, determining their efficacy only by the changes in tumor size may prove inaccurate.
Gyo Jeong Gu +7 more
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Lessons from Bacillus Calmette-Guérin: Harnessing Trained Immunity for Vaccine Development
Cells, 2020 Vaccine design traditionally focuses on inducing adaptive immune responses against a sole target pathogen. Considering that many microbes evade innate immune mechanisms to initiate infection, and in light of the discovery of epigenetically mediated ...
Samuel T. Pasco, Juan Anguita
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Scientific Reports, 2021 While the dire cardiometabolic consequences of the hypercaloric modern ‘Western’ diet are well known, there is not much information on the health impact of a high sucrose diet not inducing weight gain. Here, we tested the hypothesis that rats reared with
Omkar L. Patkar +16 more
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Segmentation based tracking of cells in 2D+time microscopy images of macrophages [PDF]
, 2023 The automated segmentation and tracking of macrophages during their migration are challenging tasks due to their dynamically changing shapes and motions. This paper proposes a new algorithm to achieve automatic cell tracking in time-lapse microscopy macrophage data.
arxiv +1 more source
Frontiers in Immunology, 2022 Kupffer cells are the primary liver resident immune cell responsible for the liver firewall function, including clearance of bacterial infection from the circulation, as they are strategically positioned inside the liver sinusoid with intimate contact ...
Mateus Eustáquio Lopes +10 more
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