Results 1 to 10 of about 1,113,017 (348)
Liposomal Dexamethasone Reduces A/H1N1 Influenza-Associated Morbidity in Mice
Frontiers in Microbiology, 2022 Re-emerging viral threats have continued to challenge the medical and public health systems. It has become clear that a significant number of severe viral infection cases are due to an overreaction of the immune system, which leads to hyperinflammation ...
Jung Won Kwon +9 more
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Microbial Biotechnology, 2022 Summary Colorectal cancer pathogenesis and progression is associated with the presence of Fusobacterium nucleatum and the reduction of acetylated derivatives of spermidine, as well as dietary components such as tannin‐rich foods.
José Miguel Mancheño +23 more
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A new era of macrophage-based cell therapy
Experimental and Molecular Medicine, 2023 Macrophages are essential innate immune cells found throughout the body that have protective and pathogenic functions in many diseases. When activated, macrophages can mediate the phagocytosis of dangerous cells or materials and participate in effective ...
Yi Rang Na +2 more
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Journal of Nanobiotechnology, 2023 Background Immune checkpoint inhibitors such as anti-programmed cell death protein 1 (PD1) block tumor growth by reinvigorating the immune system; however, determining their efficacy only by the changes in tumor size may prove inaccurate.
Gyo Jeong Gu +7 more
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Immunity, 2014 Macrophages are a diverse population of phagocytic cells that reside in tissues throughout the body. At sites of infection, macrophages encounter and engulf invading microbes. Accordingly, macrophages possess specialized effector functions to kill or coordinate the elimination of their prey.
Jordan V. Price, Russell E. Vance
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Lessons from Bacillus Calmette-Guérin: Harnessing Trained Immunity for Vaccine Development
Cells, 2020 Vaccine design traditionally focuses on inducing adaptive immune responses against a sole target pathogen. Considering that many microbes evade innate immune mechanisms to initiate infection, and in light of the discovery of epigenetically mediated ...
Samuel T. Pasco, Juan Anguita
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Scientific Reports, 2021 While the dire cardiometabolic consequences of the hypercaloric modern ‘Western’ diet are well known, there is not much information on the health impact of a high sucrose diet not inducing weight gain. Here, we tested the hypothesis that rats reared with
Omkar L. Patkar +16 more
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Frontiers in Immunology, 2022 Kupffer cells are the primary liver resident immune cell responsible for the liver firewall function, including clearance of bacterial infection from the circulation, as they are strategically positioned inside the liver sinusoid with intimate contact ...
Mateus Eustáquio Lopes +10 more
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A Catalogus Immune Muris of the mouse immune responses to diverse pathogens
Cell Death and Disease, 2021 Immunomodulation strategies are crucial for several biomedical applications. However, the immune system is highly heterogeneous and its functional responses to infections remains elusive. Indeed, the characterization of immune response particularities to
Céline Barlier +7 more
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International Journal of Molecular Sciences, 2022 Immunological memory is a crucial part of the immune defense that allows organisms to respond against previously encountered pathogens or other harmful factors. Immunological memory is based on the establishment of epigenetic modifications of the genome.
Malgorzata Kloc +3 more
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