Results 1 to 10 of about 1,130,331 (341)
Macrophage depletion disrupts immune balance and energy homeostasis. [PDF]
, 2014 Increased macrophage infiltration in tissues including white adipose tissue and skeletal muscle has been recognized as a pro-inflammatory factor that impairs insulin sensitivity in obesity.
Feng, Gen-Sheng +4 more
core +15 more sources
Liposomal Dexamethasone Reduces A/H1N1 Influenza-Associated Morbidity in Mice
Frontiers in Microbiology, 2022 Re-emerging viral threats have continued to challenge the medical and public health systems. It has become clear that a significant number of severe viral infection cases are due to an overreaction of the immune system, which leads to hyperinflammation ...
Jung Won Kwon +9 more
doaj +1 more source
A new era of macrophage-based cell therapy
Experimental and Molecular Medicine, 2023 Macrophages are essential innate immune cells found throughout the body that have protective and pathogenic functions in many diseases. When activated, macrophages can mediate the phagocytosis of dangerous cells or materials and participate in effective ...
Yi Rang Na +2 more
doaj +1 more source
European Respiratory Journal, 1994 Interest in pulmonary macrophage research has greatly increased as is now possible not only to work with the easily accessible alveolar macrophages but also with macrophages prepared from lung tissue, such as the interstitial macrophages, dendritic cells and intravascular macrophages.
M L, Lohmann-Matthes +2 more
openaire +2 more sources
Microbial Biotechnology, 2022 Summary Colorectal cancer pathogenesis and progression is associated with the presence of Fusobacterium nucleatum and the reduction of acetylated derivatives of spermidine, as well as dietary components such as tannin‐rich foods.
José Miguel Mancheño +23 more
doaj +1 more source
Journal of Nanobiotechnology, 2023 Background Immune checkpoint inhibitors such as anti-programmed cell death protein 1 (PD1) block tumor growth by reinvigorating the immune system; however, determining their efficacy only by the changes in tumor size may prove inaccurate.
Gyo Jeong Gu +7 more
doaj +1 more source
International Journal of Molecular Sciences, 2022 Immunological memory is a crucial part of the immune defense that allows organisms to respond against previously encountered pathogens or other harmful factors. Immunological memory is based on the establishment of epigenetic modifications of the genome.
Malgorzata Kloc +3 more
openaire +2 more sources
Lessons from Bacillus Calmette-Guérin: Harnessing Trained Immunity for Vaccine Development
Cells, 2020 Vaccine design traditionally focuses on inducing adaptive immune responses against a sole target pathogen. Considering that many microbes evade innate immune mechanisms to initiate infection, and in light of the discovery of epigenetically mediated ...
Samuel T. Pasco, Juan Anguita
doaj +1 more source
Scientific Reports, 2021 While the dire cardiometabolic consequences of the hypercaloric modern ‘Western’ diet are well known, there is not much information on the health impact of a high sucrose diet not inducing weight gain. Here, we tested the hypothesis that rats reared with
Omkar L. Patkar +16 more
doaj +1 more source
Investigating the suitability of high content image analysis as a tool to assess the reversibility of foamy alveolar macrophage phenotypes in vitro. [PDF]
, 2020 Many potential inhaled medicines fail during development due to the induction of a highly vacuolated or “foamy” alveolar macrophage phenotype response in pre-clinical studies.
Hoffman, Ewelina +2 more
core +2 more sources