Results 101 to 110 of about 746,406 (260)

Macrophage-based therapeutic strategies in regenerative medicine.

, 2018
Mounting evidence suggests that therapeutic cell and drug delivery strategies designed to actively harness the regenerative potential of the inflammatory response have great potential in regenerative medicine. In particular, macrophages have emerged as a
Timothy J. Koh (7918463), Kara L. Spiller (7918460)   +1 more
core  

Del-1 nanoparticles/silk fibroin hydrogel accelerates the healing of chronic skin wounds by promoting inflammation regression

陆军军医大学学报
Objective To investigate the effect of silk fibroin hydrogel loaded with developmental endothelial locus-1 (Del-1) nanoparticles on the healing of chronic skin wounds in mice.
KAN Xuewei, YAO Pingping, CHEN Jiaqi
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy

, 2018
Various delivery vectors have been integrated within biologically derived membrane systems to extend their residential time and reduce their reticuloendothelial system (RES) clearance during systemic circulation.
Chao Li (145513), Jianjun Cheng (646595), Kaimin Cai (1635064), Yifei Lu (1639471), Xinli Chen (35821), Yongzhuo Huang (1647523), Qinjun Chen (3189519), Tao Sun (91038), Yu Zhang (12946), Yujie Zhang (399434), Xi He (208289), Lisha Liu (3189510), Chen Jiang (200126), Qin Guo (125106)   +13 more
core   +1 more source

CXCL8 mediates macrophage migration in canine oral malignant melanoma

Scientific Reports
Tumor-associated macrophage (TAM) infiltration is associated with poor prognosis in human patients with melanoma. However, the mechanism by which TAMs infiltrate tumor tissues in dogs remains unclear.
Nao Okauchi, Shusaku Shibutani, Masashi Sakurai, Hiroka Yamamoto, Kazuhito Itamoto, Daiki Kato, Takayuki Nakagawa, Sadatoshi Maeda, Kenji Baba, Takuya Mizuno, Masaya Igase   +10 more
doaj   +1 more source

Loss of LpqM proteins in Mycobacterium abscessus is associated with impaired intramacrophage survival

Microbiology Spectrum
Mycobacterium abscessus, an emerging pathogen responsible for severe pulmonary infections in cystic fibrosis patients, displays either a smooth (S) or a rough (R) morphotype. Infections with M.
Yves-Marie Boudehen, Wassim Daher, Françoise Roquet-Baneres, Laurent Kremer   +3 more
doaj   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Macrophage-specific genes of S. Typhimurium D23580 are required for virulence in animal infection models.

, 2019
(A) Representation of the 45 genes, among the 68 macrophage-specific genes, in S. Typhimurium D23580 that showed an RNA-seq fold-change with FDR ≤0.05.
Michael Ibba (250023), Rocío Canals (595216), Roy R. Chaudhuri (7439600), Jay C. D. Hinton (7439615), Natalia Quinones-Olvera (7439609), Siân V. Owen (7439606), Michael Baym (606968), Melita A. Gordon (7439612), Rebecca E. Steiner (7439603)   +8 more
core   +1 more source

Disulfiram, an Anti-alcoholic Drug, Targets Macrophages and Attenuates Acute Rejection in Rat Lung Allografts

Transplant International
Macrophages contribute to post-transplant lung rejection. Disulfiram (DSF), an anti-alcoholic drug, has an anti-inflammatory effect and regulates macrophage chemotactic activity. Here, we investigated DSF efficacy in suppressing acute rejection post-lung
Nobuyuki Yoshiyasu, Rei Matsuki, Masaaki Sato, Hirokazu Urushiyama, Etsuko Toda, Etsuko Toda, Yasuhiro Terasaki, Yasuhiro Terasaki, Masaki Suzuki, Aya Shinozaki-Ushiku, Yuya Terashima, Jun Nakajima   +11 more
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source