Results 111 to 120 of about 961,596 (307)

Research progress on the interaction between glucose metabolic reprogramming and lactylation in tumors

Frontiers in Immunology
Glucose metabolic reprogramming describes the alterations in intracellular metabolic pathways in response to variations in the body’s internal environment. This metabolic reprogramming has been the subject of extensive research.
Yi Yang, Yi Yang, Yi Wu, Yi Wu, Hui Chen, Hui Chen, Zehai Xu, Zehai Xu, Ruisi Lu, Ruisi Lu, Sijie Zhang, Sijie Zhang, Rui Zhan, Rui Zhan, Qinghua Xi, Qinghua Xi, Yunfeng Jin, Yunfeng Jin   +17 more
doaj   +1 more source

Role of TGFbRII in myeloid cell mediated regenerative processes and fibroplasia [PDF]

, 2012
Tissue repair and fibrosis are controlled by the interaction of different cell lineages, their soluble factors and matrix signals. Recently, macrophages have been found to be crucial for proper tissue repair.
Ranjan, Rajeev
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Bioinformatics analysis to investigate the potential relationship between mitochondrial structure and function-related genes and the immune microenvironment in atherosclerosis

Frontiers in Cardiovascular Medicine
ObjectiveThis study aims to elucidate the interactions between genes associated with mitochondrial structure and function and the immune microenvironment in atherosclerosis.MethodsDifferentially expressed mitochondria-related genes (DE-MRGs) were ...
Hanning Yang, Yue Sun, Shumin Li, Yueyue Tang, Yuxue Wang, Yunyan Li, Yongping Lu   +6 more
doaj   +1 more source

Protein Tyrosine Phosphatase 1B (PTP1B) in the immune system [PDF]

, 2015
Journal not available online when checked 02/04/19.
Delibegovic, Mirela, Le Sommer, Samantha, Martin-Granados, Christina, Martina, Pesaresi   +3 more
core  

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Endoneurial immune interplay in peripheral nerve repair: insights and implications for future therapeutic interventions

Frontiers in Neuroscience
The mechanisms underlying axonal injury and repair in peripheral nerves, whether due to traumatic damage or autoimmune neuropathies, are complex and not yet fully understood.
Alina Sprenger-Svačina, Alina Sprenger-Svačina, Martin K. R. Svačina, Martin K. R. Svačina, Husniye G. Otlu, Husniye G. Otlu, Tong Gao, Kazim A. Sheikh, Gang Zhang   +8 more
doaj   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Corrigendum: Susceptibility to infections during acute liver injury depends on transient disruption of liver macrophage niche

Frontiers in Immunology, 2022
Mateus Eustáquio Lopes, Brenda Naemi Nakagaki, Matheus Silvério Mattos, Gabriel Henrique Campolina-Silva, Gabriel Henrique Campolina-Silva, Raquel de Oliveira Meira, Pierre Henrique de Menezes Paixão, André Gustavo Oliveira, Lucas D. Faustino, Ricardo Gonçalves, Gustavo Batista Menezes   +10 more
doaj   +1 more source

Near-infrared fluorescent nanoprobe enables noninvasive, longitudinal monitoring of graft outcome in RPE transplantation

Frontiers in Medicine
ObjectivesRetinal pigment epithelium (RPE) cell transplantation holds therapeutic promise for retinal degenerative diseases, but longitudinal monitoring of graft survival and efficacy remains clinically challenging.
Guanzhou Di, Chen Lu, Mengting Xue, Limin Zheng, Limin Zheng, Weiqi Li, Runmin Xie, Xinpei Yuan, Xu Zhen, Min Wu, Xiying Mao, Songtao Yuan   +11 more
doaj   +1 more source