Results 11 to 20 of about 1,133,037 (342)

Pulmonary macrophages [PDF]

open access: yesEuropean Respiratory Journal, 1994
Interest in pulmonary macrophage research has greatly increased as is now possible not only to work with the easily accessible alveolar macrophages but also with macrophages prepared from lung tissue, such as the interstitial macrophages, dendritic cells and intravascular macrophages.
M L, Lohmann-Matthes   +2 more
openaire   +2 more sources

Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity

open access: yesCell Reports, 2020
Summary: Mitofusin 2 (Mfn2) plays a major role in mitochondrial fusion and in the maintenance of mitochondria-endoplasmic reticulum contact sites. Given that macrophages play a major role in inflammation, we studied the contribution of Mfn2 to the ...
Juan Tur   +9 more
doaj   +1 more source

A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]

open access: yes, 2011
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Bewley, M.A.   +10 more
core   +5 more sources

The Macrophage Paradox [PDF]

open access: yesImmunity, 2014
Macrophages are a diverse population of phagocytic cells that reside in tissues throughout the body. At sites of infection, macrophages encounter and engulf invading microbes. Accordingly, macrophages possess specialized effector functions to kill or coordinate the elimination of their prey.
Price, Jordan V., Vance, Russell E.
openaire   +2 more sources

Ursolic acid enhances macrophage autophagy and attenuates atherogenesis [PDF]

open access: yes, 2016
Macrophage autophagy has been shown to be protective against atherosclerosis. We previously discovered that ursolic acid (UA) promoted cancer cell autophagy.
Fan, Daping   +7 more
core   +2 more sources

Identification of a highly active tannase enzyme from the oral pathogen Fusobacterium nucleatum subsp. polymorphum

open access: yesMicrobial Cell Factories, 2018
Background Tannases are tannin-degrading enzymes that have been described in fungi and bacteria as an adaptative mechanism to overcome the stress conditions associated with the presence of these phenolic compounds.
Julen Tomás-Cortázar   +10 more
doaj   +1 more source

Ratio of CD68/CD163 in Breast Carcinoma with and without Axillary Lymph Node Metastatic

open access: yesFolia Medica Indonesiana, 2021
Tumor and its microenvironment can interact each other. Macrophage is part of tumor microenvironment. New drugs targeting specific superficial receptor of macrophage or cytokine of macrophage polarization have been found.
Priangga Adi Wiratama, Willy Sandhika
doaj   +1 more source

Leukocyte-Specific Morrbid Promotes Leukocyte Differentiation and Atherogenesis

open access: yesResearch, 2023
Monocyte-to-M0/M1 macrophage differentiation with unclear molecular mechanisms is a pivotal cellular event in many cardiovascular diseases including atherosclerosis.
Di Xiang   +22 more
doaj   +1 more source

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis [PDF]

open access: yes, 2017
Macrophages specialize in removing lipids and debris present in the atherosclerotic plaque. However, plaque progression renders macrophages unable to degrade exogenous atherogenic material and endogenous cargo including dysfunctional proteins and ...
Ali, Sahl   +19 more
core   +2 more sources

Mesoporous Silica Nanoparticles as a Potential Platform for Vaccine Development against Tuberculosis

open access: yesPharmaceutics, 2020
The increasing emergence of new strains of Mycobacterium tuberculosis (Mtb) highly resistant to antibiotics constitute a public health issue, since tuberculosis still constitutes the primary cause of death in the world due to bacterial infection. Mtb has
Sandra Montalvo-Quirós   +6 more
doaj   +1 more source

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