Results 11 to 20 of about 1,143,350 (343)

Pulmonary macrophages [PDF]

open access: yesEuropean Respiratory Journal, 1994
Interest in pulmonary macrophage research has greatly increased as is now possible not only to work with the easily accessible alveolar macrophages but also with macrophages prepared from lung tissue, such as the interstitial macrophages, dendritic cells and intravascular macrophages.
M L, Lohmann-Matthes   +2 more
openaire   +2 more sources

Memory Macrophages

open access: yesInternational Journal of Molecular Sciences, 2022
Immunological memory is a crucial part of the immune defense that allows organisms to respond against previously encountered pathogens or other harmful factors. Immunological memory is based on the establishment of epigenetic modifications of the genome.
Malgorzata Kloc   +3 more
openaire   +2 more sources

Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity

open access: yesCell Reports, 2020
Summary: Mitofusin 2 (Mfn2) plays a major role in mitochondrial fusion and in the maintenance of mitochondria-endoplasmic reticulum contact sites. Given that macrophages play a major role in inflammation, we studied the contribution of Mfn2 to the ...
Juan Tur   +9 more
doaj   +1 more source

Ursolic acid enhances macrophage autophagy and attenuates atherogenesis [PDF]

open access: yes, 2016
Macrophage autophagy has been shown to be protective against atherosclerosis. We previously discovered that ursolic acid (UA) promoted cancer cell autophagy.
Fan, Daping   +7 more
core   +2 more sources

Homegrown Macrophages [PDF]

open access: yesImmunity, 2016
Macrophages residing in different organs have diverse gene-expression programs. Mass et al. (2016) propose that this diversity develops "at home"-within those organs-after the recruitment of a common precursor that had not made prior commitments to diversity.
Ki-Wook, Kim   +3 more
openaire   +2 more sources

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis [PDF]

open access: yes, 2017
Macrophages specialize in removing lipids and debris present in the atherosclerotic plaque. However, plaque progression renders macrophages unable to degrade exogenous atherogenic material and endogenous cargo including dysfunctional proteins and ...
Ali, Sahl   +19 more
core   +2 more sources

Identification of a highly active tannase enzyme from the oral pathogen Fusobacterium nucleatum subsp. polymorphum

open access: yesMicrobial Cell Factories, 2018
Background Tannases are tannin-degrading enzymes that have been described in fungi and bacteria as an adaptative mechanism to overcome the stress conditions associated with the presence of these phenolic compounds.
Julen Tomás-Cortázar   +10 more
doaj   +1 more source

A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]

open access: yes, 2011
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Bewley, M.A.   +10 more
core   +5 more sources

Leukocyte-Specific Morrbid Promotes Leukocyte Differentiation and Atherogenesis

open access: yesResearch, 2023
Monocyte-to-M0/M1 macrophage differentiation with unclear molecular mechanisms is a pivotal cellular event in many cardiovascular diseases including atherosclerosis.
Di Xiang   +22 more
doaj   +1 more source

Treating Macrophages with Anti-inflammatory Nanoparticles as a Strategy to Improve Muscle Repair [PDF]

open access: yes, 2019
The macrophage is an immune cell that is involved in host defense. More recent research, however, has revealed that they also play a central role in mediating the skeletal muscle regenerative process.
Yan, Derek
core   +1 more source

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