Results 191 to 200 of about 420,110 (262)

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

open access: yesAdvanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang   +12 more
wiley   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult-Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single-Center Experience. [PDF]

open access: yesTher Apher Dial
Ueda M   +15 more
europepmc   +1 more source

Differential phagocytosis induces diverse macrophage activation states in malignant gliomas. [PDF]

open access: yesJ Immunother Cancer
Lakshmanachetty S   +12 more
europepmc   +1 more source

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