Results 281 to 290 of about 4,994,603 (399)

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Differential phagocytosis induces diverse macrophage activation states in malignant gliomas. [PDF]

J Immunother Cancer
Lakshmanachetty S, Riemondy K, Sanford B, Donson A, Chen V, Balakrishnan I, Prince EW, Hankinson T, Dahl N, Vibhakar R, Foreman N, Venkatraman S, Mitra SS.   +12 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Ngf/TrKA signal is associated with macrophage activation of acute kidney injury in mice. [PDF]

Ren Fail
Tang Q, Liu K, Tang Y, Xiao Q, Huang L, Li G, Wang L, Li Y.   +7 more
europepmc   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

AIF-1 Drives Corneal Neovascularization by Promoting Inflammatory Macrophage Activation via the MAPK and PI3K/AKT/mTOR Signaling Pathways. [PDF]

Invest Ophthalmol Vis Sci
Li Q, Bao Q, Wei C, Xie Y, Zhao S, Yan H, Wu F, Li W, Liu X, Gao H.   +9 more
europepmc   +1 more source

IN VITRO AUGMENTATION OF MACROPHAGE-ACTIVATING-FACTOR RELEASE FROM PERIPHERAL BLOOD CELLS OF CANCER PATIENTS BY A DNA FRACTION FROM MYCOBACTERIUM BOVIS BCG

, 1990
Harukazu Mashiba, Keiko Matsunaga, Hirotsugu Tomoda, Motonosuke Furusawa   +3 more
openalex   +2 more sources

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Reversal of filarial serpin Wb123-urokinase plasminogen activator receptor mediated alternative macrophage activation by monoclonal antibody. [PDF]

PLoS Negl Trop Dis
Upadhyay P, Munjal A, Mondal A, Singh G, Mukherjee S, Siwach S, Chandoulla M, Kaushik MC, Gupta PK, Pati S, Singh S.   +10 more
europepmc   +1 more source

Silica‐induced initiation of circular ZC3H4RNA/ZC3H4 pathway promotes the pulmonary macrophage activation

The FASEB Journal, 2018
Xiyue Yang, Jing Wang, Ze-wei Zhou, Rong Jiang, Jie Huang, Lulu Chen, Zhouli Cao, Han Chu, B. Han, Yusi Cheng, J. Chao   +10 more
semanticscholar   +1 more source