Results 261 to 270 of about 2,007,152 (308)
Some of the next articles are maybe not open access.
Regulators of macrophage activation
European Journal of Immunology, 2011AbstractMacrophages are ubiquitous phagocytes that can constitute up to 15% of the cellular content of tissues. These heterogeneous cells of the innate immune system perform important functions during health and disease. Equipped with receptors for the T helper cell cytokines INF‐γ and IL‐4, macrophages undergo specific activation programs during Th1 ...
openaire +3 more sources
A novel phenotype for an activated macrophage: the type 2 activated macrophage
Journal of Leukocyte Biology, 2002AbstractActivated macrophages were used as antigen presenting cells (APCs) to determine the extent to which these APCs could influence an adaptive immune response. We show that activated macrophages induced a strong polarized Th1-like T cell response that was predominated by IFN-γ.
Charles F, Anderson, David M, Mosser
openaire +2 more sources
Alternative activation of macrophages
Nature Reviews Immunology, 2003The classical pathway of interferon-gamma-dependent activation of macrophages by T helper 1 (T(H)1)-type responses is a well-established feature of cellular immunity to infection with intracellular pathogens, such as Mycobacterium tuberculosis and HIV.
openaire +2 more sources
Activation of Murine Macrophages
Current Protocols in Immunology, 1994AbstractMacrophages can act as potent effector cells of the immune response. Cytokine signals generated during an immune response activate macrophages in a complex cascade of events. Activated macrophages are qualitatively different from mature resident tissue macrophages and from immature inflammatory macrophages.
openaire +2 more sources
Arginine and Macrophage Activation
2011In order to perform their functions, macrophages must be activated either by Th1-type cytokines, such as interferon-gamma which is called classical activation or M1, or by Th2-type cytokines, such as IL-4, IL-10, IL-13, etc. referred as alternative activation or M2.
Comalada, M. +4 more
openaire +3 more sources
Mycobacteria and macrophage activation
Research in Microbiology, 1990Recent studies that challenged some older concepts have led to the following conclusions: 1) During an infection of mice with M. bovis, BCG macrophages are activated according to certain criteria, but the increase in their bactericidal or bacteriostatic activity is limited to a small number of bacteria species; 2) interferon-gamma can activate ...
openaire +2 more sources
Macrophage Activation for Tumor Cytotoxicity: Mechanisms of Macrophage Activation by Lymphokines
1980[No abstract available]
M. S. Meltzer, RUCO, Luigi, Leonard Ej
openaire +3 more sources
Macrophage Activation by Immunostimulatory DNA
2000Macrophage/dendritic cells and B cells remain the only cell types where direct responses to CpG DNA are well established. The role of macrophages in vivo in DNA clearance and the potent cytokine induction in macrophages and dendritic cells places them in the central role in the in vivo response to foreign DNA.
Stacey, K. J. +3 more
openaire +5 more sources
Macrophage activation syndrome in malaria
Rheumatology International, 2009Macrophage activation syndrome (MAS) is a clinical syndrome caused by an excessive proliferation of T lymphocytes and well-differentiated macrophages; an entity distinct from malignant histiocytosis. Although rheumatologic conditions are the common cause of MAS, a wide range of infections are also seen to cause MAS.
Rashna, Dass +6 more
openaire +2 more sources
Macrophage Activation Syndrome
Arthritis & RheumatologyMacrophage activation syndrome (MAS) is a state of immune hyperactivation that can result in life‐threatening multisystem end‐organ dysfunction. Often termed a “cytokine storm,” MAS occurs among the rheumatic diseases most typically in Still's disease but also in systemic lupus erythematosus and Kawasaki disease.
openaire +2 more sources