Results 81 to 90 of about 646,237 (202)

Ybp1 and Gpx3 signaling in Candida albicans govern hydrogen peroxide-induced oxidation of the Cap1 transcription factor and macrophage escape [PDF]

, 2013
Peer reviewedPublisher ...
Alarco AM, Alessandra da Silva Dantas, Brian A. Morgan, Christopher G. McKenzie, Deborah A. Smith, Donna M. MacCallum, Elizabeth A. Veal, Janet Quinn, Lars-Peter Erwig, Miranda J. Patterson, Sam Sherston, Vazquez-Torres A, Wysong DR   +12 more
core   +1 more source

Regulation of macrophage activation by lactylation in lung disease

Frontiers in Immunology
Lactylation is a process where lactate, a cellular metabolism byproduct, is added to proteins, altering their functions. In the realm of macrophage activation, lactylation impacts inflammatory response and immune regulation.
Yungeng Wei, Hua Guo, Shixing Chen, Xiao Xiao Tang, Xiao Xiao Tang   +4 more
doaj   +1 more source

Pro-inflammatory macrophage activation does not require inhibition of oxidative phosphorylation

EMBO Reports
Pro-inflammatory macrophage activation is a hallmark example of how mitochondria serve as signaling organelles. Oxidative phosphorylation sharply decreases upon classical macrophage activation, as mitochondria are thought to shift from ATP production ...
Andréa B Ball, Anthony E Jones, Kaitlyn B Nguyễn, Amy Rios, Nico Marx, Wei Yuan Hsieh, Krista Yang, Brandon R Desousa, Kristen K O Kim, Michaela Veliova, Zena Marie del Mundo, Orian S Shirihai, Cristiane Benincá, Linsey Stiles, Steven J Bensinger, Ajit S Divakaruni   +15 more
doaj   +1 more source

Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation

eLife, 2016
Macrophage activation/polarization to distinct functional states is critically supported by metabolic shifts. How polarizing signals coordinate metabolic and functional reprogramming, and the potential implications for control of macrophage activation ...
Anthony J Covarrubias, Halil Ibrahim Aksoylar, Jiujiu Yu, Nathaniel W Snyder, Andrew J Worth, Shankar S Iyer, Jiawei Wang, Issam Ben-Sahra, Vanessa Byles, Tiffany Polynne-Stapornkul, Erika C Espinosa, Dudley Lamming, Brendan D Manning, Yijing Zhang, Ian A Blair, Tiffany Horng   +15 more
doaj   +1 more source

The Pathogen Candida albicans Hijacks Pyroptosis for Escape from Macrophages

mBio, 2014
The fungal pathogen Candida albicans causes macrophage death and escapes, but the molecular mechanisms remained unknown. Here we used live-cell imaging to monitor the interaction of C. albicans with macrophages and show that C. albicans kills macrophages
Nathalie Uwamahoro, Jiyoti Verma-Gaur, Hsin-Hui Shen, Yue Qu, Rowena Lewis, Jingxiong Lu, Keith Bambery, Seth L. Masters, James E. Vince, Thomas Naderer, Ana Traven   +10 more
doaj   +1 more source

Functional aspects, phenotypic heterogeneity, and tissue immune response of macrophages in infectious diseases

Infection and Drug Resistance, 2019
Jorge Rodrigues de Sousa,1,2 Pedro Fernando Da Costa Vasconcelos,2,3 Juarez Antonio Simões Quaresma1–41Tropical Medicine Center, Federal University of Pará, Belém, PA, Brazil; 2Evandro Chagas Institute, Ministry of Health ...
de Sousa JR, Da Costa Vasconcelos PF, Quaresma JAS   +2 more
doaj  

Makrofag Pengekspresi Il-1? Serta Respons Inflamasi Sistemik Pada Fiksasi Interna Dini Fraktur Femur Tertutup Lebih Rendah Dibandingkan Dengan Yang Tertunda [PDF]

, 2007
Fiksasi interna merupakan salah satu modalitas terapi dalam penangananfraktur. Fiksasi interna dini dan tertunda masih menjadi suatu perdebatan karenaadanya perbedaan komplikasi yang ditimbulkan, terutama yang berhubungandengan respons inflamasi sistemik.
Astawa, P. (P), Bakta, M. (M), K, B. (Budha)   +2 more
core  

M1 M2 Macrophage Expression in Menstrual Blood Flakes of Women with Endometriosis [PDF]

, 2016
Objectives: to measure and prove the increase of panmacrophage, macrophages M1 and M2 expression and decrease of ratio of M1/M2 in menstrual blood flakes of women with endometriosis.
Haslinda, Y. (Yulisa), Hendarto, H. (Hendy), Hoesin, F. (Faroek)   +2 more
core  

Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype.

PLoS ONE, 2017
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by cellular phenotype alterations and deposition of extracellular matrix proteins.
Shweta Joshi, Alok R Singh, Simon S Wong, Muamera Zulcic, Min Jiang, Annie Pardo, Moises Selman, James S Hagood, Donald L Durden   +8 more
doaj   +1 more source

The Immune System: the ultimate fractionated cyber-physical system

, 2013
In this little vision paper we analyze the human immune system from a computer science point of view with the aim of understanding the architecture and features that allow robust, effective behavior to emerge from local sensing and actions.
Talcott, Carolyn
core   +2 more sources