Results 1 to 10 of about 256,905 (322)
Macrophage Activation Syndrome in Viral Sepsis [PDF]
VirusesMacrophage activation syndrome (MAS) is a life-threatening systemic hyperinflammatory syndrome triggered by various infections, particularly viral infections, autoimmune disorders, and malignancy. The condition is characterized by an increased production
Despoina Papageorgiou +2 more
doaj +4 more sources
Macrophage Activation Syndrome [PDF]
The Indian Journal of Pediatrics, 2015 Macrophage activation syndrome (MAS) is a potentially life-threatening complication of rheumatic diseases such as systemic juvenile idiopathic arthritis (sJIA) and systemic lupus erythematosus. It is often considered a type of secondary hemophagocytic lymphohistiocytosis (HLH) and results from over-activation of T lymphocytes and macrophages leading to
Clarke, Sarah L N +2 more
core +9 more sources
Macrophage activation syndrome revealing Hodgkin´s lymphoma: a case report
The Pan African Medical Journal, 2021 Macrophage activation syndrome (MAS) is a rare immunologic syndrome, rapidly fatal in the absence of specific etiological treatment. It is defined by clinical, biological and cyto-histological criteria. Numerous etiologies have been described in MAS, the
Mustapha Mechtoune +2 more
doaj +2 more sources
The Immunology of Macrophage Activation Syndrome [PDF]
Frontiers in Immunology, 2019 Synonymous with secondary hemophagocytic lymphohistiocytosis, macrophage activation syndrome (MAS) is a term used by rheumatologists to describe a potentially life-threatening complication of systemic inflammatory disorders, most commonly systemic ...
Courtney B. Crayne +3 more
doaj +3 more sources
Macrophage activation syndrome and COVID-19 [PDF]
Inflammation and Regeneration, 2020 An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating pandemic. As we have not developed curative medicine and effective vaccine, the end of this life-threatening infectious disease is still unclear.
Ryo Otsuka, Ken-ichiro Seino
doaj +4 more sources
Macrophage activation syndrome in systemic lupus erythematosus - a case report
Journal of Education, Health and Sport, 2023 Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition that results from the immune system hyperactivation. The primary form of HLH appears mainly in children and is caused by a genetically determined failure of NK and T cells ...
Maciej Rogala +7 more
doaj +3 more sources
Macrophage activation syndrome, a rare complication of primary Sjögren’s syndrome: a case report [PDF]
Journal of Medical Case Reports, 2019 Background The association of macrophage activation syndrome and primary Sjögren’s syndrome has been rarely reported in the literature. We report the first observation of this association in Africa, south of the Sahara, and we discuss the diagnosis and ...
B. S. Kane +10 more
doaj +2 more sources
A Review on Macrophage Activation Syndrome
Journal of Pure and Applied Microbiology, 2019 MAS, which is currently grouped under secondary or acquired haemophagocytic lymphohistiocytosis (sHLH), is a rare and fatal disorder that results from excess activation of T-cells and macrophages.
Preeti Sharma +4 more
doaj +3 more sources
Neutralization of IFN-γ reverts clinical and laboratory features in a mouse model of macrophage activation syndrome. [PDF]
, 2018 BACKGROUND: The pathogenesis of macrophage activation syndrome (MAS) is not clearly understood: a large body of evidence supports the involvement of mechanisms similar to those implicated in the setting of primary hemophagocytic lymphohistiocytosis ...
Bracaglia, Claudia +10 more
core +3 more sources
Heterogeneity of macrophage activation syndrome and treatment progression [PDF]
Frontiers in ImmunologyMacrophage activation syndrome (MAS) is a rare complication of autoimmune inflammatory rheumatic diseases (AIIRD) characterized by a progressive and life-threatening condition with features including cytokine storm and hemophagocytosis.
Yuanji Dong, Ting Wang, Huaxiang Wu
doaj +2 more sources