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Macrophage Activation Syndrome in Viral Sepsis [PDF]

Viruses
Macrophage activation syndrome (MAS) is a life-threatening systemic hyperinflammatory syndrome triggered by various infections, particularly viral infections, autoimmune disorders, and malignancy. The condition is characterized by an increased production
Despoina Papageorgiou, Charalambos Gogos, Karolina Akinosoglou   +2 more
doaj   +4 more sources

Macrophage activation syndrome in a child with varicella: a case report [PDF]

Journal of Medical Case Reports
Background Macrophage activation syndrome is a severe, potentially fatal condition that belongs to the group of hemophagocytic lymphohistiocytosis.
H. Mateiko, O. Synoverska, M. Matvisiv, Z. Vovk, N. Horbal   +4 more
doaj   +2 more sources

Macrophage activation syndrome revealing Hodgkin´s lymphoma: a case report

The Pan African Medical Journal, 2021
Macrophage activation syndrome (MAS) is a rare immunologic syndrome, rapidly fatal in the absence of specific etiological treatment. It is defined by clinical, biological and cyto-histological criteria. Numerous etiologies have been described in MAS, the
Mustapha Mechtoune, Rajae Tissir, Ilias Tazi   +2 more
doaj   +2 more sources

Adult-onset Still’s disease with secondary macrophage activation syndrome: a case report

Italian Journal of Medicine, 2023
We describe a case of adult-onset Still’s disease (AOSD) with secondary macrophage activation syndrome. AOSD is a rare disease with unknown origin. Rarely it’s complicated by secondary macrophage activation syndrome, which is a life-threatening disorder.
Giuseppe Nicoletti, Antonio Bonelli, Rocco Clemente, Simona Ciuffreda, Gaetano Dentamaro, Agata Tiziana La Masa, Vito Lascaro, Pasquale Santarcangelo   +7 more
doaj   +3 more sources

Macrophage activation syndrome in systemic lupus erythematosus - a case report

Journal of Education, Health and Sport, 2023
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition that results from the immune system hyperactivation. The primary form of HLH appears mainly in children and is caused by a genetically determined failure of NK and T cells ...
Maciej Rogala, Karol Lorenc, Klaudia Jabłońska, Michał Kuc, Olga Bielawska, Tomasz Łoś, Kamila Giżewska, Marta Gulbicka   +7 more
doaj   +3 more sources

Macrophage activation syndrome, a rare complication of primary Sjögren’s syndrome: a case report [PDF]

Journal of Medical Case Reports, 2019
Background The association of macrophage activation syndrome and primary Sjögren’s syndrome has been rarely reported in the literature. We report the first observation of this association in Africa, south of the Sahara, and we discuss the diagnosis and ...
B. S. Kane, M. Niasse, A. Faye, N. D. Diack, B. Djiba, M. Dieng, M. Sow, A. C. Ndao, N. Diagne, S. Ndongo, A. Pouye   +10 more
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Heterogeneity of macrophage activation syndrome and treatment progression [PDF]

Frontiers in Immunology
Macrophage activation syndrome (MAS) is a rare complication of autoimmune inflammatory rheumatic diseases (AIIRD) characterized by a progressive and life-threatening condition with features including cytokine storm and hemophagocytosis.
Yuanji Dong, Ting Wang, Huaxiang Wu
doaj   +2 more sources

Macrophage activation syndrome complicating early course of adult-onset Still’s disease [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2021
Introduction. Adult-onset Still’s disease is a rare inflammatory disorder of unknown etiology. It can be complicated by macrophage activation syndrome, a potentially life-threatening condition. While macrophage activation syndrome and adult-onset Still’s
Božić Ksenija, Elez Marija, Glišić Branislava   +2 more
doaj   +1 more source

Impact of Interleukin-1 Blockade on the Development of Macrophage Activation Syndrome in Still Disease: Incidence and Diagnostic Validity of the EULAR/ACR/PRINTO 2016 MAS Classification Criteria. [PDF]

Arthritis Rheumatol
Erkens RGA, Rogani G, Huber L, Verwoerd A, Schonenberg-Meinema D, van den Berg JM, Armbrust W, Legger GE, Kamphuis S, Schatorjé EJH, Hoppenreijs EPAH, Swart JF, Jansen MHA, van Loosdregt J, Vastert SJ.   +14 more
europepmc   +3 more sources

mTORC1 links pathology in experimental models of Still’s disease and macrophage activation syndrome

Nature Communications, 2022
Still’s disease is an inflammatory syndrome linked to the development of further immune dysregulation and hypercytokinaemia termed macrophage activation syndrome.
Zhengping Huang, Xiaomeng You, Liang Chen, Yan Du, Kailey Brodeur, Hyuk Jee, Qiang Wang, Grace Linder, Roxane Darbousset, Pierre Cunin, Margaret H. Chang, Alexandra Wactor, Brian M. Wauford, Marc J. C. Todd, Kevin Wei, Ying Li, Anais Levescot, Yoichiro Iwakura, Virginia Pascual, Nicole E. Baldwin, Pierre Quartier, Tianwang Li, Maria T. Gianatasio, Robert P. Hasserjian, Lauren A. Henderson, David B. Sykes, Elizabeth D. Mellins, Scott W. Canna, Julia F. Charles, Peter A. Nigrovic, Pui Y. Lee   +30 more
doaj   +1 more source