Results 91 to 100 of about 551,256 (383)
Emerging Infectious Diseases, 2019 Ebola virus disease (EVD) is associated with elevated cytokine levels, and hypercytokinemia is more pronounced in fatal cases. This type of hyperinflammatory state is reminiscent of 2 rheumatologic disorders known as macrophage activation syndrome and ...
Anita K. McElroy +13 more
doaj +1 more source
Macrophage activation syndrome in children with Kikuchi-Fujimoto disease
Pediatric Rheumatology Online Journal, 2023 Background Kikuchi-Fujimoto disease (KFD) is typically a benign, self-limiting inflammatory disease. However, some patients may have a prolonged or recurrent disease course, or present with life-threatening complications such as macrophage activation ...
Zixuan Shen +4 more
doaj +1 more source
Immunomodulation in sepsis-induced macrophage activation syndrome in children
Indian Pediatrics Case Reports, 2023 Background: Sepsis is a state of systemic inflammation due to an infectious etiology that may lead to multisystem dysfunction, hemodynamic instability, and even death.
Ashna Kumar +4 more
doaj +1 more source
Network Topologies and Dynamics Leading to Endotoxin Tolerance and Priming in Innate Immune Cells [PDF]
PLoS Comput Biol 8(5): e1002526, 2012, 2012 The innate immune system, acting as the first line of host defense, senses and adapts to foreign challenges through complex intracellular and intercellular signaling networks. Endotoxin tolerance and priming elicited by macrophages are classic examples of the complex adaptation of innate immune cells.
arxiv +1 more source
Novel Molecular Mechanisms in the Development of Non-Alcoholic Steatohepatitis. [PDF]
, 2016 Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in adults and children worldwide. NAFLD has become a severe health issue and it can progress towards a more severe form of the disease, the non-alcoholic ...
Feldstein, Ariel E, Povero, Davide
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.Abstract Defining the CSF cytokine/chemokine and injury biomarker signature of glial fibrillary acidic protein (GFAP) autoimmunity can inform immunopathogenesis. CSF GFAP‐IgG‐positive samples (N = 98) were tested for 17 cytokines/chemokines, neurofilament light chain (NfL), and GFAP (ELLA, Bio‐Techne).
Yahel Segal +11 more
wiley +1 more source
Pediatric Rheumatology Online Journal, 2020 This study aimed to determine the influence of tocilizumab (TCZ) in modifying the clinical and laboratory features of macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis (s-JIA).
M. Shimizu +15 more
semanticscholar +1 more source
Systemic Lupus Erythematosus Presenting as Macrophage Activation Syndrome [PDF]
Journal of Clinical and Diagnostic Research, 2018 Macrophage Activation Syndrome (MAS), a potentially life threatening condition belongs to acquired cause of Hemophagocytic lymphohistiocytosis (HLH) group of diseases more often found in children than adults.
Satyabrata Guru +3 more
doaj +1 more source
A Tutorial of Cyber-Syndrome viewed from Cyber-Physical-Social-Thinking Space and Maslow's Hierarchy of Needs [PDF]
arXiv, 2021 With the increase of active Internet users, various physical, social, and mental disorders have recently emerged because of the excessive use of technology. Cyber-Syndrome is known as the condition that appears due to the excessive interaction with the cyberspace, and it affects the users' physical, social, and mental states.
arxiv
Managing Adult-onset Still's disease: The effectiveness of high-dosage of corticosteroids as first-line treatment in inducing the clinical remission. Results from an observational study [PDF]
, 2019 To assess the effectiveness of the treatment with high dosage of corticosteroids (CCSs), as first-line therapy, in inducing remission in naïve Adult-onset Still's disease (AOSD) patients compared with low dosage of CCSs, after 6 months.
Berardicurti O. +7 more
core +1 more source