Results 251 to 260 of about 261,254 (319)

MACROPHAGE ACTIVATION SYNDROME IN A PATIENT WITH STILL S DISEASE

Gerardo Rodríguez, Letícia Fioravante da Silveira, Leonardo André Denti, Andreza Neves Ramos, L Bischoff, Mateus Camozzato de Padua, Tatiana Freitas Tourinho, Maria Lúcia Lemos Lopes, Thiago Willers, Rafael Coradin, Felipe Giovani Tawil Aubin, Lílian Scussel Lonzetti, Carla Forgiarini Saldanha   +12 more
openalex   +1 more source

Molecular stratification of antiphospholipid syndrome through integrative analysis of the whole‐blood RNA transcriptome

Arthritis &Rheumatology, Accepted Article.
Objective Antiphospholipid syndrome (APS) is a thrombo‐inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)‐positive patients using whole‐blood transcriptomics.
Amala Ambati, Feiyang Ma, Katarina Kmetova, Sherwin Navaz, Claire K. Hoy, Cyrus Sarosh, Ajay Tambralli, Erika Navarro‐Mendoza, Johann E. Gudjonsson, J. Michelle Kahlenberg, Jacqueline A. Madison, Alí Duarte‐García, Jason S. Knight, Yu Zuo   +13 more
wiley   +1 more source

Effective Treatment of Macrophage Activation Syndrome Linked to Systemic Lupus Erythematosus Using Interleukin-1 Inhibitor. [PDF]

Cureus
Barlas N, Kaur IP, Kuzhuppilly Arcilla C, Kaeley GS, Thway M.   +4 more
europepmc   +1 more source

[Clinical characteristics and treatment outcomes of macrophage activation syndrome in adults: A case series of 67 patients].

, 2019
Yao Hh, Wang Yn, X Zhang, Zhao Jx, Yanjie Jia, Z Wang, Li Zg   +6 more
openalex   +2 more sources

Interleukin‐18 levels are associated with disease course in patients with Still's disease treated with IL‐1 inhibitors

Arthritis &Rheumatology, Accepted Article.
Objective To evaluate the prognostic utility of circulating Interleukin‐18 (IL‐18) levels in predicting disease activity, macrophage activation syndrome (MAS), and disease course in Still's disease (SD) patients receiving first‐line IL‐1 inhibitors (IL‐1i).
Matteo Trevisan, Manuela Pardeo, Ivan Caiello, Claudia Bracaglia, Arianna de Matteis, Valentina Matteo, Elena Loricchio, Fabrizio De Benedetti, Giusi Prencipe   +8 more
wiley   +1 more source

T-ing up the storm: pathogenic cycling lymphocytes in the biology of macrophage activation syndrome. [PDF]

Pediatr Rheumatol Online J
Lam MT, Jiang CL, Lee PY.
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

Arthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Intravenous Anakinra for Treating Macrophage Activation Syndrome in Adult-Onset Still's Disease. [PDF]

Eur J Case Rep Intern Med
Bitik B, Şenturk M, Kibaroglu S, Yildirim T, Tezcan ME, Zeyneloglu P, Yucel AE.   +6 more
europepmc   +1 more source

A New Era for Using Natural Pigments: The Case of the C50 Carotenoid Called Bacterioruberin

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Haloarchaea are extremophilic microorganisms belonging to the Archaea domain that require high salt concentrations to live, thus inhabiting ecosystems like salty ponds, salty marshes, or extremely salty lagoons. They are more abundant and widely distributed worldwide than initially expected.
Micaela Giani, Elena Valdés, José María Miralles‐Robledillo, Guillermo Martínez, Carmen Pire, Rosa María Martínez‐Espinosa   +5 more
wiley   +1 more source