Results 21 to 30 of about 551,256 (383)

Macrophage activation syndrome complicating early course of adult-onset Still’s disease [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2021
Introduction. Adult-onset Still’s disease is a rare inflammatory disorder of unknown etiology. It can be complicated by macrophage activation syndrome, a potentially life-threatening condition. While macrophage activation syndrome and adult-onset Still’s
Božić Ksenija, Elez Marija, Glišić Branislava   +2 more
doaj   +1 more source

Macrophage Activation Syndrome [PDF]

International Journal of Surgical Pathology, 2013
Zespół aktywacji makrofaga (<i>macrophage activation syndrome</i> – MAS) jest ciężkim powikłaniem układowych chorób tkanki łącznej, głównie układowej postaci młodzieńczego idiopatycznego zapalenia stawów, tocznia rumieniowatego układowego oraz choroby Stilla u dorosłych.
Nidhi Aggarwal, Rohit Aggarwal
  +7 more sources

The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS)

Annals of the Rheumatic Diseases, 2023
Objective Haemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) are life-threatening systemic hyperinflammatory syndromes that can develop in most inflammatory contexts. They can progress rapidly, and early identification and
B. Shakoory, A. Geerlinks, M. Wilejto, K. Kernan, M. Hines, M. Romano, D. Piskin, A. Ravelli, Rashmi Sinha, D. Aletaha, C. Allen, H. Bassiri, E. Behrens, J. Carcillo, Linda Carl, W. Chatham, J. Cohen, R. Cron, Erik Drewniak, A. Grom, L. Henderson, A. Horne, M. Jordan, K. Nichols, G. Schulert, S. Vastert, E. Demirkaya, R. Goldbach-Mansky, F. De Benedetti, R. Marsh, S. Canna   +30 more
semanticscholar   +1 more source

Expansion of CD4dimCD8+T cells characterizes macrophage activation syndrome and other secondary HLH.

Blood, 2022
CD8+ T-cell activation has been demonstrated to distinguish patients with primary and infection-associated hemophagocytic lymphohistiocytosis (pHLH and iaHLH) from patients with early sepsis.
A. De Matteis, M. Colucci, M. Rossi, I. Caiello, P. Merli, N. Tumino, V. Bertaina, M. Pardeo, C. Bracaglia, F. Locatelli, F. De Benedetti, G. Prencipe   +11 more
semanticscholar   +1 more source

Immune cartography of macrophage activation syndrome in the COVID-19 era

Nature Reviews Rheumatology, 2021
A hyperinflammatory ‘cytokine storm’ state termed macrophage activation syndrome (MAS), culminating from a complex interplay of genetics, immunodeficiency, infectious triggers and dominant innate immune effector responses, can develop across disparate ...
D. McGonagle, A. Ramanan, C. Bridgewood
semanticscholar   +1 more source

Macrophage activation syndrome after COVID-19 infection in a patient with systemic juvenile idiopathic arthritis [PDF]

, 2023
Macrophage activation syndrome is a serious, potentially fatal complication of the systemic form of juvenile idiopathic arthritis. It shares some common characteristics with the multisystem inflammatory disease in children, which is a late complication ...
Belcheva, Milena, Boyadzhiev, Martin, Dyankova, Yoana, Georgieva, Miglena, Iotova, Violeta, Krumova, Darina, Rasheva, Niya, Shivachev, Petar, Varbanova, Boryana, Zhelezova, Veronika   +9 more
core   +2 more sources

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

Case Report: VEXAS Syndrome: From Mild Symptoms to Life-Threatening Macrophage Activation Syndrome

Frontiers in Immunology, 2021
Recently, a novel disorder coined VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome was identified in patients with adult-onset inflammatory syndromes, often accompanied by myelodysplastic syndrome1.
F. Staels, A. Betrains, Sherida Woei-A-Jin, N. Boeckx, M. Beckers, A. Bervoets, M. Willemsen, Barbara Neerinckx, S. Humblet-Baron, D. Blockmans, S. Vanderschueren, R. Schrijvers   +11 more
semanticscholar   +1 more source

Effects of a mesoporous bioactive glass on osteoblasts, osteoclasts and macrophages [PDF]

J. Colloid Interface Sci. 528, 309-320 (2018), 2021
A mesoporous bioactive glass (MBG) of molar composition 75SiO2-20CaO-5P2O5 (MBG-75S) has been synthetized as a potential bioceramic for bone regeneration purposes. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), nitrogen adsorption studies and transmission electron microscopy (TEM) demonstrated that MBG-75Spossess a highly ...
arxiv   +1 more source

Ruxolitinib for Refractory Macrophage Activation Syndrome Complicating Adult-Onset Still’s Disease

European Journal of Rheumatology, 2022
Macrophage activation syndrome is the most frequent life-threatening complication of adult-onset Still’s disease. This is a nearly fatal case of a young patient, which has been refractory to corticosteroids, anakinra, tocilizumab, cyclosporine A, and ...
O. Levy, A. Apel, Hossam Alhdor, A. Mizrachi, N. Agmon-Levin, M. Koren-Michowitz, M. Amit-Vazina   +6 more
semanticscholar   +1 more source