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Macrophage Activation Syndrome
The Journal of the Association of Physicians of India, 2018 Hemophagocytic lymphohistiocytosis (HLH), or termed macrophage activation syndrome (MAS) when associated with rheumatic disorders, is a frequently fatal complication of infections, rheumatic disorders, and hematopoietic malignancies. Clinically, HLH/MAS is a life-threatening condition that is usually diagnosed among febrile hospitalized patients ...
Eloseily, Esraa M., Cron, Randy Q.
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Incorporation and effects of mesoporous SiO2-CaO nanospheres loaded with ipriflavone on osteoblast/osteoclast cocultures [PDF]
Eur. J. Pharm. Biopharm. 133, 258-268 (2018), 2021 Mesoporous nanospheres in the system SiO2-CaO (NanoMBGs) with a hollow core surrounded by a radial arrangement of mesopores were characterized, labeled with FITC (FITC-NanoMBGs) and loaded with ipriflavone (NanoMBG-IPs) in order to evaluate their incorporation and their effects on both osteoblasts and osteoclasts simultaneously and maintaining the ...
arxiv +1 more source
Macrophage activation syndrome revealing Hodgkin´s lymphoma: a case report
The Pan African Medical Journal, 2021 Macrophage activation syndrome (MAS) is a rare immunologic syndrome, rapidly fatal in the absence of specific etiological treatment. It is defined by clinical, biological and cyto-histological criteria. Numerous etiologies have been described in MAS, the
Mustapha Mechtoune +2 more
doaj +1 more source
Adult-onset Still’s disease with secondary macrophage activation syndrome: a case report
Italian Journal of Medicine, 2023 We describe a case of adult-onset Still’s disease (AOSD) with secondary macrophage activation syndrome. AOSD is a rare disease with unknown origin. Rarely it’s complicated by secondary macrophage activation syndrome, which is a life-threatening disorder.
Giuseppe Nicoletti +7 more
doaj +1 more source
ACR Open Rheumatology, 2020 The objective of this study was to report the benefit of a therapeutic approach consisting of intravenous (IV) continuous anakinra (recombinant human interleukin‐1 receptor antagonist) infusions in treating severely ill adult patients with secondary ...
Luke Adam Monteagudo +2 more
semanticscholar +1 more source
Intravenous administration of anakinra in children with macrophage activation syndrome
Pediatric Rheumatology Online Journal, 2021 Background Subcutaneous anakinra is an interleukin-1 inhibitor used to treat juvenile idiopathic arthritis. Recent reports suggest anakinra can be a valuable addition to the treatment of COVID-19 associated cytokine storm syndrome and the related ...
Omkar Phadke +4 more
semanticscholar +1 more source
Macrophage Activation Syndrome
Definitions, 2020 Reactive hemophagocytic lymphohistiocytosis (HLH), or macrophage activation syndrome (MAS), is an unusual complication of systemic inflammatory diseases.1 Its association with juvenile idiopathic arthritis (JIA) is rare and treatment must be immediate ...
semanticscholar +1 more source
Oral Etoposide for Dengue Induced Haemophagocytic Lymphohistiocytosis Presented as Acute Liver Failure [PDF]
Journal of Clinical and Diagnostic Research, 2022 Dengue fever is not an uncommon arboviral infection in lieu of tropical geography. The gravity of the disease ranges from an Outpatient Department (OPD) visits for febrile illness to haemorrhagic complications like shock. Hereby, authors report a case of
Bharat Patodiya +4 more
doaj +1 more source
Macrophage activation syndrome triggered by coeliac disease: a unique case report [PDF]
, 2016 Background: Macrophage activation syndrome is described as a “clinical syndrome of hyperinflammation resulting in an uncontrolled and ineffective immune response” in the context of an autoinflammatory or rheumatic disease.
May, J, Palman, J, Pilkington, C
core +1 more source
Hyperinflammation: On the pathogenesis and treatment of macrophage activation syndrome
Acta paediatrica, 2021 Macrophage activation syndrome (MAS) is a subtype of hemophagocytic lymphohistiocytosis (HLH) diseases. The underlying mechanism of these life‐threatening disorders is impaired granule‐mediated cytotoxicity exerted by natural killer (NK) cells and T ...
U. Andersson
semanticscholar +1 more source