Results 21 to 30 of about 83,539 (262)

Cyclo (MQCNS) has the potential to treat ischemic stroke

Neural Regeneration Research, 2023
We previously found that monocyte locomotion inhibitory factor has a neuroprotective effect on ischemic brain injury during the acute phase of stroke.
Zhibing Song, Xinyu Li, Mengting Lv, Yuchen Guo, Shanshan Deng, Yuefan Zhang, Tiejun Li   +6 more
doaj   +1 more source

Receptor agonists of macrophage migration inhibitory factor [PDF]

Bioorganic & Medicinal Chemistry Letters, 2010
The cytokine MIF is involved in inflammation and cell proliferation via pathways initiated by its binding to the transmembrane receptor CD74. MIF also promotes AMPK activation with potential benefits for response to myocardial infarction and ischemia-reperfusion.
William L, Jorgensen, Sunilkumar, Gandavadi, Xin, Du, Alissa A, Hare, Alexander, Trofimov, Lin, Leng, Richard, Bucala   +6 more
openaire   +2 more sources

Hepatocellular Expression of Macrophage Migration Inhibitory Factor (MIF) Is Associated with Ischemia-Reperfusion Injury After Liver Transplantation [PDF]

Revista do Colégio Brasileiro de Cirurgiões
Introduction: Ischemia-reperfusion injury (IRI) is a major determinant of initial graft function after liver transplantation (LT), directly influencing the incidence of early dysfunction and short-term clinical outcomes.
RODRIGO HUMBERTO VILAR PONTES FILHO, CAMILA XAVIER BRITO, SERENA DÁFNE DO CARMO SILVA, AGNALDO SOARES LIMA, FRANCISCO GUILHERME CANCELA E PENNA, FERNANDA MARIA FARAGE OSÓRIO, NÍKOLAS KNUPP THOME, CRISTIANO XAVIER LIMA, PAULA VIEIRA TEIXEIRA VIDIGAL   +8 more
doaj   +4 more sources

The relevance of serum macrophage migratory inhibitory factor and cognitive dysfunction in patients with cerebral small vascular disease

Frontiers in Aging Neuroscience, 2023
Cerebral small vascular disease (CSVD) is a common type of cerebrovascular disease, and an important cause of vascular cognitive impairment (VCI) and stroke.
Jianhua Zhao, Xiaoting Wang, Qiong Li, Chengbiao Lu, Shaomin Li   +4 more
doaj   +1 more source

Migration Inhibitory Factor and Macrophage Bactericidal Function [PDF]

Infection and Immunity, 1972
A homogeneous population of immunologically active lymphocytes was obtained from peritoneal exudates of guinea pigs with delayed hypersensitivity to bovine gamma globulin (BGG). The lymphocytes were cultured with and without BGG for 24 hr, and cell-free supernatant fluids were then assayed simultaneously for their ability to influence two ...
H B, Simon, J N, Sheagren
openaire   +2 more sources

Phyllolobium chinense Fisch Flavonoids (PCFF) Suppresses the M1 Polarization of LPS-Stimulated RAW264.7 Macrophages by Inhibiting NF-κB/iNOS Signaling Pathway

Frontiers in Pharmacology, 2020
BackgroundM1 macrophage plays an important role in inflammatory reaction. In this study, potential anti-inflammatory effect of Phyllolobium chinense Fisch flavonoids (PCFF) was assessed via Zebrafish acute inflammation model in vivo and LPS-induced pro ...
Hua Fan, Qiong Wu, Longping Peng, Du Li, Yidan Dong, Min Cao, Ping Liu, Xu Wang, Xudong Hu, Youhua Wang   +9 more
doaj   +1 more source

Dengue virus enhances thrombomodulin and ICAM-1 expression through the macrophage migration inhibitory factor induction of the MAPK and PI3K signaling pathways. [PDF]

PLoS ONE, 2013
Dengue virus (DV) infections cause mild dengue fever (DF) or severe life-threatening dengue hemorrhagic fever (DHF). The mechanisms that cause hemorrhage in DV infections remain poorly understood.
Trai-Ming Yeh, Shu-Hsiang Liu, Kao-Chang Lin, Chieh Kuo, Shu-Yun Kuo, Tzuu-Yuan Huang, Yong-Ren Yen, Rong-Kun Wen, Lien-Cheng Chen, Tsai-Feng Fu   +9 more
doaj   +1 more source

Macrophage migration inhibitory factor in rheumatoid pericarditis [PDF]

Arthritis & Rheumatism, 1977
AbstractThe pericardial effusion in a case of rheumatoid pericarditis was studied to determine whether immune complexes and mediators of cellular immunity, represented by migration inhibitory factor (MIF), were present. MIF‐like activity was detected in the pericardial fluid, but only traces of immune complexes were revealed by ultracentrifugation. The
M, Andreis, E R, Hurd
openaire   +2 more sources

Macrophage migration inhibitory factor and glucocorticoid sensitivity [PDF]

Rheumatology, 2006
Glucocorticoids (GCs) are widely used in the treatment of inflammatory diseases including rheumatoid arthritis (RA). Treatment with GC is associated with significant dose-dependent side-effects. The pro-inflammatory cytokine macrophage migration inhibitory factor (MIF) has emerged in recent years as a candidate factor which could regulate GC ...
D, Aeberli, M, Leech, E F, Morand
openaire   +2 more sources

Macrophage Migration Inhibitory Factor in Protozoan Infections [PDF]

Journal of Parasitology Research, 2012
Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a general trend, MIF participates in the control of parasite burden at the expense of promoting tissue damage ...
Marcelo T. Bozza, Yuri C. Martins, Letícia A. M. Carneiro, Claudia N. Paiva   +3 more
openaire   +3 more sources