Effects of stanniocalcin-1 overexpressing hepatocellular carcinoma cells on macrophage migration.
Human stanniocalcin-1 (STC1) is a glycoprotein known to participate in inflammation and tumor progression. However, its role in cancer-macrophage interaction at the tumor environment is not known.
Cherry C T Leung, Chris K C Wong
doaj +1 more source
Macrophage Migration Inhibitory Factor in Cardiovascular Disease [PDF]
The highly conserved and archetypical yet atypical cytokine macrophage migration inhibitory factor (MIF) fulfills pleiotropic immune functions in many acute and chronic inflammatory diseases. Recent evidence has emerged from both expression and functional studies to implicate MIF in various aspects of cardiovascular disease. The present review is aimed
Alma, Zernecke +2 more
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Macrophage migration inhibitory factor in Nodding syndrome
Nodding syndrome (NS) is a catastrophic and enigmatic childhood epilepsy, accompanied by multiple neurological impairments and neuroinflammation. Of all the infectious, environmental and psychological factors associated with NS, the major culprit is Onchocerca Volvulus (Ov)–a parasitic worm transmitted to human by blackflies.
Gil Benedek +10 more
openaire +4 more sources
Macrophage migration inhibitory factor in acute kidneyinjury
Acute kidney injury (AKI) is a complex clinical syndrome with multiple etiologies and pathogenesis, which lacks early biomarkers and targeted therapy. Recently, macrophage migration inhibitory factor (MIF) family protein have received increasing attention owing to its pleiotropic protein molecule character in acute kidney injury, where it performed a ...
Yiwei Du, Hao Hao, Heng Ma, Hongbao Liu
openaire +3 more sources
Anti-TNF therapy reduces serum levels of chemerin in rheumatoid arthritis: a new mechanism by which anti-TNF might reduce inflammation. [PDF]
BACKGROUND: Chemerin is a specific chemoattractant for macrophages and dendritic cells (DC). In addition, it can rapidly stimulate macrophage adhesion to extracellular matrix proteins and adhesion molecules and is able to activate fibroblast-like ...
Marieke M J Herenius +5 more
doaj +1 more source
Interaction of macrophage-migration-inhibitory factor with haematin [PDF]
Macrophage-migration-inhibitory factor (MIF) is retained by S-hexylglutathione–agarose but is not specifically eluted in high yield. Human liver MIF was purified in high yield using retention by phenyl-agarose at low ionic strength and cation-exchange FPLC as described for bovine lens MIF [Rosengren, Bucala, Åman, Jacobsson, Odh, Metz and Rorsman (1996)
J L, Pennock +3 more
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The Potential Role of Cytokines and Growth Factors in the Pathogenesis of Alzheimer’s Disease
Alzheimer’s disease (AD) is one of the most prominent neurodegenerative diseases, which impairs cognitive function in afflicted individuals. AD results in gradual decay of neuronal function as a consequence of diverse degenerating events.
Gilbert Ogunmokun +13 more
doaj +1 more source
Macrophage migration inhibitory factor, a role in COPD [PDF]
Macrophage migration inhibitor factor (MIF) is a pluripotent cytokine associated with several different inflammatory conditions, but its role within lung inflammation and chronic obstructive pulmonary disease (COPD) is unclear. This study aimed to examine MIF in both stable COPD and during acute exacerbations (AECOPD).
Gunnar R. Husebø +6 more
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TA-MSCs, TA-MSCs-EVs, MIF: their crosstalk in immunosuppressive tumor microenvironment
As an important component of the immunosuppressive tumor microenvironment (TME), it has been established that mesenchymal stem cells (MSCs) promote the progression of tumor cells.
Zhenghou Zhang +11 more
doaj +1 more source
The Dichotomic Role of Macrophage Migration Inhibitory Factor in Neurodegeneration [PDF]
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine expressed by different cell types and exerting multiple biological functions. It has been shown that MIF may be involved in several disorders, including neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS), Parkinson disease (PD), and Huntington disease (HD), that
Maria Sofia Basile +7 more
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