Results 111 to 120 of about 1,228,727 (302)

Natural Melanin/Alginate Hydrogels Achieve Cardiac Repair through ROS Scavenging and Macrophage Polarization

Advancement of science, 2021
The efficacy of cardiac regenerative strategies for myocardial infarction (MI) treatment is greatly limited by the cardiac microenvironment. The combination of reactive oxygen species (ROS) scavenging to suppress the oxidative stress damage and ...
Jin Zhou, Wei Liu, Xiaoyi Zhao, Yifan Xian, Wei Wu, Xiao Zhang, N. Zhao, F. Xu, Changyong Wang   +8 more
semanticscholar   +1 more source

Boolean modeling of macrophage polarization upon immune stimulation and SARS-CoV-2 infection [PDF]

, 2022
Macrophages are specialized cells of the immune system that can polarize into different phenotypes depending on local conditions, classically an inflammatory macrophage (M1) and alternatively an anti-inflammatory macrophage (M2).
Bermúdez Paiva, Viviam Solangeli
core  

The complex TIE between macrophages and angiogenesis [PDF]

, 2020
Macrophages are primarily known as phagocytic immune cells, but they also play a role in diverse processes, such as morphogenesis, homeostasis and regeneration.
Anghelina M., Avraham‐Davidi I., Baer C., Bailey A. S., Barnett F. H., Bonnardel J., Chakarov S., Chen L., Coffelt S. B., Corliss B. A., Cursiefen C., Daly C., Davies L. C., Davies L. C., De Palma M., De Palma M., De Palma M., De Palma M., De Palma M., De Spiegelaere W., DeFalco T., Deshmane S. L., Detry B., Dimova I., Dimova I., Eklund L., Elamaa H., Eubank T. D., Fantin A., Ferrari G., Fukuhara S., Ganta V. C., Ganta V. C., García S., Gerri C., Grunewald M., Guo L., Gurevich D. B., Hamm A., Hazan A. D., He H., Hoeffel G., Itoh M., Jetten N., Kim M., Kochhan E., Korhonen E. A., Korpelainen E. I., Krishnasamy K., Kumar A. H., Leibovich S. J., Lim H. Y., Liu C., Lucas T., Master Z., Metharom P., Michaeli S., Moldovan N. I., Moore E. M., Mueller S. B., Murdoch C., Murray P. J., Patel A. S., Polverini P. J., Potente M., Pucci F., Saharinen P., Saharinen P., Schif‐Zuck S., Schmeisser A., Seaman S. A., Seok S. H., Spiller K. L., Venneri M. A., Vestweber D., Webster N. L., West M. E. D., Willenborg S., Yamamoto S., Zajac E., Zenker D., Zhang W.   +81 more
core   +2 more sources

Research progress of traditional Chinese medicine influencing macrophage polarization

Journal of Holistic Integrative Pharmacy, 2021
[Abstract]: Recently, with advancements in science and technology, humans have found that macrophages play essential roles in many diseases, which has become a new focus of research on disease diagnosis and treatment.
Shuang GAO, Zhe-Sheng CHEN, Xuanyu CHEN, Jing LI   +3 more
doaj  

Modulation of macrophage polarization by iron-based nanoparticles

Medical Review, 2023
Macrophage polarization is an essential process involved in immune regulation. In response to different microenvironmental stimulation, macrophages polarize into cells with different phenotypes and functions, most typically M1 (pro-inflammatory) and M2 ...
Ding He, Zhang Yuxin, Mao Yu, Li Yan, Shen Yan, Sheng Jingyi, Gu Ning   +6 more
doaj   +1 more source

A potential therapeutic target in traditional Chinese medicine for ulcerative colitis: Macrophage polarization

Frontiers in Pharmacology, 2022
Intestinal macrophages are the main participants of intestinal immune homeostasis and intestinal inflammation. Under different environmental stimuli, intestinal macrophages can be polarized into classical activated pro-inflammatory phenotype (M1) and ...
Zhihua Yang, Shanshan Lin, Wanying Feng, Yangxi Liu, Zhihui Song, Gui-Xia Pan, Yuhang Zhang, Xiang-dong Dai, X. Ding, Lu Chen, Yi Wang   +10 more
semanticscholar   +1 more source

The role of metabolic remodeling in macrophage polarization and its effect on skeletal muscle regeneration [PDF]

, 2019
Macrophages are crucial for tissue homeostasis. Based on their activation, they might display classical/M1 or alternative/M2 phenotypes. M1 macrophages produce pro-inflammatory cytokines, reactive oxygen species (ROS), and nitric oxide (NO).
Alessio Torcinaro, Elisabetta Ferraro, Fielding RA, Francesca De Santa, Galván-Peña S, Hard GC, Huang X, Kawanishi N, Laura Vitiello, Munder M, Ménégaut L, Ohtsu A, Tidball JG, Zhang X   +13 more
core   +1 more source

PGC-1α inhibits M2 macrophage polarization and alleviates liver fibrosis following hepatic ischemia reperfusion injury

Cell Death Discovery, 2023
Oxidative stress can induce inflammation, promoting macrophage polarization and liver fibrosis following hepatic ischemia-reperfusion (I/R). Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) has anti-oxidant and anti-inflammatory ...
Yanting Zhang, Linzhong Zhang, Yanmian Zhao, Jing He, Yanghao Zhang, Xiuying Zhang   +5 more
doaj   +1 more source

Nrf2 Deficiency Exacerbated CLP-Induced Pulmonary Injury and Inflammation through Autophagy- and NF-κB/PPARγ-Mediated Macrophage Polarization

Cells, 2022
The balance between M1 and M2 macrophage polarization is involved in the regulation of pulmonary inflammation. Nuclear factor erythroid-derived 2-like 2 (Nfe2l2, also known as Nrf2), a nuclear transcription factor, is reported to play protective roles in
Jing Luo, Jin Wang, Jing Zhang, A-ming Sang, Xujun Ye, Zhenshun Cheng, Xinyi Li   +6 more
semanticscholar   +1 more source

Nuclear receptor corepressor 1 deficiency exacerbates asthma by modulating macrophage polarization

Cell Death Discovery, 2023
Macrophage polarization plays an important role in asthma. Nuclear receptor corepressor 1 (NCOR1) plays an important role in metabolic and cardiovascular diseases by regulating the function of macrophages. The aim of this research was to examine the role
Chenchen Hou, Lifeng Yan, Ke Sun, Tianyu Zhou, Yuxin Zou, Weining Xiong, Sheng-Zhong Duan   +6 more
doaj   +1 more source