Results 151 to 160 of about 139,946 (311)

Identification of polarized macrophage subsets in zebrafish

open access: yeseLife, 2015
While the mammalian macrophage phenotypes have been intensively studied in vitro, the dynamic of their phenotypic polarization has never been investigated in live vertebrates. We used the zebrafish as a live model to identify and trail macrophage subtypes.
Nguyen-Chi, M   +11 more
openaire   +6 more sources

Carbon Dot‐Linked Hydrogel for TAMs Transform: Spatiotemporal Manipulation to Reshape Tumor Microenvironment

open access: yesAdvanced Materials, EarlyView.
The CDs crosslinked egg white hydrogel loaded with lipopolysaccharide (LPS) and CA170 (TTF‐L‐C) can realize spatiotemporal tumor‐associated macrophages (TAMs) transformation from multi‐level dimensions, including spatial recruitment, cell phenotype reprogramming, and immune checkpoint molecule blockade.
Lingyun Li   +8 more
wiley   +1 more source

Effects of Ox-LDL on Macrophages NAD(P)H Autofluorescence Changes by Two-photon Microscopy [PDF]

open access: yesDans European Nano Systems Worshop - ENS 2005, Paris : France (2005), 2007
Ox-LDL uptakes by macrophage play a critical role in the happening of atherosclerosis. Because of its low damage on observed cells and better signal-to- background ratio, two-photon excitation fluorescence microscopy is used to observe NAD(P)H autofluorescence of macrophage under difference cultured conditions- bare cover glass, coated with fibronectin
arxiv  

M2-like macrophages in the fibrotic liver protect mice against lethal insults through conferring apoptosis resistance to hepatocytes. [PDF]

open access: yes, 2017
Acute injury in the setting of liver fibrosis is an interesting and still unsettled issue. Most recently, several prominent studies have indicated the favourable effects of liver fibrosis against acute insults.
Bai, Li   +13 more
core   +2 more sources

Materials Advances in Devices for Heart Disease Interventions

open access: yesAdvanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra   +11 more
wiley   +1 more source

The Polarization Defect of Wiskott-Aldrich Syndrome Macrophages Is Linked to Dislocalization of the Arp2/3 Complex [PDF]

open access: bronze, 2000
Stefan Linder   +5 more
openalex   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

open access: yesAdvanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou   +10 more
wiley   +1 more source

Leveraging a comprehensive unbiased RNAseq database to characterize human monocyte-derived macrophage gene expression profiles within commonly employed in vitro polarization methods

open access: yesScientific Reports
Macrophages are pivotal innate immune cells which exhibit high phenotypic plasticity and can exist in different polarization states dependent on exposure to external stimuli.
Timothy Smyth   +4 more
doaj   +1 more source

A Benzenediamine Analog FC-99 Drives M2 Macrophage Polarization and Alleviates Lipopolysaccharide- (LPS-) Induced Liver Injury

open access: yesMediators of Inflammation, 2019
Macrophages have variable functional phenotypes, high diversity, and plasticity and are involved in the pathogenesis of sepsis-induced liver injury. Alteration of macrophage polarization through activated (M1) macrophage to alternatively activated (M2 ...
Wei Gong   +4 more
doaj   +1 more source

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