Results 221 to 230 of about 1,184,411 (272)
COL1A1, a major component of ECM, contributes to chemoresistance and poor prognosis in ovarian cancer. Halofuginone (HF) attenuates CAF‐secreted COL1A1 through mTOR‐eIF2α‐ATF4 axis. Notably, HF disrupts collagen deposition to form the looser ECM and facilitates CD8+ T cell infiltration, partially via M2‐M1 macrophage polarization to enhance ...
Wenxin Li+8 more
wiley +1 more source
Mechanosensitivity of macrophage polarization: comparing small molecule leukadherin-1 to substrate stiffness. [PDF]
Joshi H+5 more
europepmc +1 more source
In this study, a targeting PFKFB4 biomimetic codelivery system is developed to improve paclitaxel efficacy by inducing ferroptosis in SCLC. This system enhances immune cell infiltration and cytokine secretion, activating anti‐tumor immunity. Combined with anti‐PD‐L1, it boosts immune responses, offering a novel therapeutic strategy for overcoming ...
Xiang Liu+9 more
wiley +1 more source
Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro. [PDF]
Liu M+5 more
europepmc +1 more source
The impact of topography on the secretome of adipose‐derived stem cells (ADSCs) has the potential for promoting tendon regeneration. The secretome generated from ADSCs on aligned structure has a potent effect in promoting cell migration, proliferation, tenogenic differentiation, macrophage M2 polarization, and tendon mechanical function recovery ...
Qiuzi Long+14 more
wiley +1 more source
Macrophage Polarization in Virus-Host Interactions
Yongming Sang+2 more
openalex +1 more source
HTLV-1 p13 Protein Hijacks Macrophage Polarization and Promotes T-Cell Recruitment. [PDF]
Moles R+11 more
europepmc +1 more source
Silk Fibroin Nanoparticles for Enhanced Cuproptosis and Immunotherapy in Pancreatic Cancer Treatment
Cuproptosis can be triggered via intracellular copper overload mediated by elesclomol (ES).Enhancing ES‐Cu's tumor targeting and circulation stability can efficiently induce tumor cuproptosis. TSF@ES‐Cu protect ES‐Cu, target tumors via natural RGD sequences, and release through multi‐responsiveness.
Si Gao+7 more
wiley +1 more source