Results 231 to 240 of about 166,541 (336)

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

The Role of Mitochondrial Regulation in Macrophage Polarization: Implications for the Pathogenesis of Rheumatoid Arthritis. [PDF]

J Inflamm Res
Li P, Wang G, Peng Z, Zhang L, Yang F, Wei Y, Pan M, Zang H, Zhou M.   +8 more
europepmc   +1 more source

CD154 restricts helminth-induced macrophage polarization and proliferation while promoting tissue residence [PDF]

Mariana Suárez‐Martins, James E Parkinson, Lili Zhang, Brian H. K. Chan, Gayle Cocita Baldwin, Rebecca J. Dodd, Conor M. Finlay, Pedro H. Papotto, Judith E. Allen, Álvaro Díaz   +9 more
openalex   +1 more source

Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization [PDF]

, 2015
Kun Liu, Enpeng Zhao, Ghulam Ilyas, Gadi Lalazar, Yu Lin, Muhammad Haseeb, Kathryn E. Tanaka, Mark J. Czaja   +7 more
openalex   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Sputum from Individuals with Primary Ciliary Dyskinesia Drives M2-like Macrophage Polarization. [PDF]

Lung
Wåhlander J, Schmidt T, Hansen CR, Kahn R, Påhlman LI.   +4 more
europepmc   +1 more source

Image 2_Sphingosine-1-phosphate stimulates colorectal cancer tumor microenvironment angiogenesis and induces macrophage polarization via macrophage migration inhibitory factor.tif

Fang Wu (267711), Zhaode Feng (12056603), Xuan Wang (55634), Yingcong Guo (16859641), Bingcong Wu (21547319), Shuheng Bai (9870203), Ning Lan (487553), Min Chen (147733), Juan Ren (733592)   +8 more
openalex   +1 more source

Nuclear Receptor Nr4a2 Promotes Alternative Polarization of Macrophages and Confers Protection in Sepsis [PDF]

, 2015
Sahil Mahajan, Ankita Saini, Vemika Chandra, Ravikanth Nanduri, Rashi Kalra, Ella Bhagyaraj, Neeraj Khatri, Pawan Gupta   +7 more
openalex   +1 more source

Hepatocyte‐Derived Extracellular Vesicles Deliver miR‐328‐3p to Trigger PP2A‐B56δ–Mediated p‐NLRP3S295‐Dependent Metaflammation in Macrophages upon Microcystin‐LR Exposure

Advanced Science, EarlyView.
Hepatocyte‐derived extracellular vesicles deliver miR‐328‐3p to trigger PP2A‐B56δ–mediated p‐NLRP3S295‐dependent metaflammation in macrophages upon microcystin‐LR exposure. 2‐DG, 2‐deoxy‐D‐glucose. B56δ, protein phosphatase 2A‐B56δ. ER, endoplasmic reticulum. iHD‐EV, inducible hepatocyte‐derived extracellular vesicles. IP3R, inositol 1,4,5‐triphosphate
Jia‐Shen Wu, Xin‐Yu Zhang, Xin‐Yu Ma, Yue‐Yue Wei, Lei‐Lei Wang, Ze‐Bang Du, Xiao‐Gang Xia, Lin Che, Dong‐Bei Guo, Han‐Ying Zheng, You‐Liang Yao, Wen‐Gang Li, Yu‐Chun Lin, Zhong‐Ning Lin   +13 more
wiley   +1 more source

Graphene and Its Derivatives as Modulators of Macrophage Polarization in Cutaneous Wound Healing. [PDF]

Cells
Lasocka I, Skibniewski M, Pasternak I, Wróblewska A, Biernacka Z, Skibniewska E, Szulc-Dąbrowska L, Kalbacova MH.   +7 more
europepmc   +1 more source