Results 231 to 240 of about 139,946 (311)

Suppressors of Cytokine Signaling 2 and 3 Diametrically Control Macrophage Polarization [PDF]

, 2013
Shaun Spence, Amy Fitzsimons, Caroline R. Boyd, Julia R. Kessler, Denise Fitzgerald, Joanne Elliott, Joan Ní Gabhann, Siobhán Smith, Antonio Sica, Emily Hams, Sean P. Saunders, Caroline A. Jefferies, Padraic G. Fallon, Daniel F. McAuley, Adrien Kissenpfennig, James A. Johnston   +15 more
openalex   +1 more source

Tumor Microenvironment On‐A‐Chip and Single‐Cell Analysis Reveal Synergistic Stromal–Immune Crosstalk on Breast Cancer Progression

Advanced Science, EarlyView.
Using a 3D tumor microenvironment (TME)‐on‐a‐chip model, tumor–stromal–immune crosstalk in triple‐negative breast cancer is studied, revealing the TME's combinatorial effect on cancer progression. Integrating single‐cell transcriptomic analysis demonstrates metabolic reprogramming via the kynurenine pathway, highlighting the complex TME cellular ...
Kalpana Ravi, Yining Zhang, Lydia Sakala, Twinkle Jina Minette Manoharan, Barbara Pockaj, Joshua LaBaer, Jin G. Park, Mehdi Nikkhah   +7 more
wiley   +1 more source

Phosphatidylserine-targeting antibody induces M1 macrophage polarization, promotes myeloid derived suppressor cell differentiation and boosts tumor-specific immunity [PDF]

, 2013
Xianming Huang, Yi Yin, Dan Ye, Rolf A. Brekken, Philip E. Thorpe   +4 more
openalex   +1 more source

A CLDN18.2‐Targeted Nanoplatform Manipulates Magnetic Hyperthermia Spatiotemporally for Synergistic Immunotherapy in Gastric Cancer

Advanced Science, EarlyView.
CLDN18.2 is a highly selective biomarker exposed in gastric cancer. A CLDN18.2‐specific antibody 1D5 conjugated fluorescence‐magnetic nanoparticle is developed for image‐guided precision theragnostics. Under the assistance of sensitive FMI and deep‐penetrating MPI for tracing and timing the optimal nanoparticle dosage, combining α‐PD1 therapy with ...
Xueying Wang, Hui Hui, Jing Han, Ting Guo, Yiding Wang, Lin Meng, Cong Chen, Jie He, Xiaoyong Guo, Fuyu Zhong, Hong Du, Jie Tian, Xiaofang Xing, Yang Du, Jiafu Ji   +14 more
wiley   +1 more source

A Tailored Hydrogel With Local Glycemia Management, Antioxidant Activity, and Photothermal Antibacterial Properties for Diabetic Wound Healing

Advanced Science, EarlyView.
A multifunctional wound dressing (ACG gels) with antioxidant, local glycocontrol, and antibacterial properties to promote diabetic wound healing. Au‐CeO2 dumbbells effectively eliminate ROS, protecting cells from oxidative stress‐induced damage while exhibiting significant near‐infrared photothermal antibacterial activity.
Bangguo Zhou, Yangying Duan, Wenhao Li, Tao Chen, Jincheng Wang, Manting Cao, Guohao Lin, Ke Yang, Zhangqi Lai, Wencheng Wu   +9 more
wiley   +1 more source

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid [PDF]

, 2014
Oscar R. Colegio, Ngoc-Quynh Chu, Alison L. Szabo, Thach Chu, Anne Marie Rhebergen, Vikram Jairam, Nika Cyrus, Carolyn Brokowski, Stephanie C. Eisenbarth, Gillian M. Phillips, Gary W. Cline, Andrew J. Phillips, Ruslan Medzhitov   +12 more
openalex   +1 more source

Ultrasound‐Assisted H2 Transmitter Enables Hydrogen‐Gene Therapy to Prevent Anesthesia/Surgery‐Induced Cognitive Impairment

Advanced Science, EarlyView.
Postoperative cognitive dysfunction (POCD) remains a challenge with no effective treatments. This study introduces a novel hydrogen‐gene therapy strategy, combining focused ultrasound and siRNA delivery via hydrogen emitters, to repair neuroinflammation in a precise and controlled manner.
Ruonan Zhan, Yan Fang, Chuyun Lou, Nan Chen, Xuan Mo, Bo Jiao, Mengke Liu, Yangxi Zhao, Weichen Xu, Huixiong Xu, Haohao Yin, Yi Zhang   +11 more
wiley   +1 more source

Serum-Glucocorticoid Regulated Kinase 1 Regulates Alternatively Activated Macrophage Polarization Contributing to Angiotensin II–Induced Inflammation and Cardiac Fibrosis

, 2012
Min Yang, Jiao Zheng, Yanjv Miao, Ying Wang, Wei Cui, Jun Guo, Shulan Qiu, Yalei Han, Lixin Jia, Hui‐Hua Li, Jizhong Cheng, Jie Du   +11 more
openalex   +1 more source

Collagen VI regulates peripheral nerve regeneration by modulating macrophage recruitment and polarization [PDF]

, 2014
Peiwen Chen, Matilde Cescon, Gaia Zuccolotto, Lucilla Nobbio, Cristina Colombelli, Monica Filaferro, G. Vitale, M. Laura Feltri, Paolo Bonaldo   +8 more
openalex   +1 more source

Macrophage Polarization-Introduction [PDF]

Journal of Clinical & Cellular Immunology, 2015
openaire   +1 more source