Results 271 to 280 of about 166,541 (336)

Xibining Inhibition of the Pi3k-Akt Pathway Reduces M1 Macrophage Polarization to Ameliorate Koa Synovial Inflammation and Nociceptive Sensitization

Lishi Jie, Li Zhang, Houyu Fu, Junfeng Kang, Zeling Huang, Zaishi Zhu, Songjiang Yin, Peng Wu, Peimin Wang, Wei Mei, Xiaochen Li   +10 more
openalex   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Sphinganine inhibits macrophage polarization and protects against sepsis-induced intestinal injury. [PDF]

World J Gastroenterol
Chen YF, Wang ZT, Zhao J, Tang JG, Zhang BY.   +4 more
europepmc   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Advances in the regulation of macrophage polarization by the tumor microenvironment. [PDF]

Discov Oncol
Peng M, Zhu Y, Hu Y, Wen J, Huang W.
europepmc   +1 more source

Mechanistic study on how the Tet1/ARF-p53 pathway affects idiopathic pulmonary fibrosis through macrophage polarization

Yanfeng Wang, Xiaotong Guo, Ting Wang, Shaojin Wang   +3 more
openalex   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Aroclor 1254 inhibits anti-inflammatory macrophage polarization through an AhR-dependent mechanism. [PDF]

J Endocr Soc
Behan-Bush RM, Kilburg E, Liszewski JN, Schrodt MV, Sander EA, Klingelhutz AJ, Ankrum JA.   +6 more
europepmc   +1 more source

BMSC-Derived Exosomes Attenuate Rat Osteoarthritis by Regulating Macrophage Polarization through PINK1/Parkin Signaling Pathway [PDF]

Beibei Li, Enpu Shen, Zhiwen Wu, Hui Qi, Cheng’ai Wu, Danping Liu, Xu Jiang   +6 more
openalex   +1 more source