Results 181 to 190 of about 114,838 (266)

Regulation of macrophage polarization in chronic airway inflammatory diseases: immune interactions, metabolic reprogramming, and beyond. [PDF]

Front Immunol
Zhang H, Meng C, Zhu D.
europepmc   +1 more source

LACC1 attenuates LPS-induced acute lung injury by inhibiting inflammatory response in alveolar macrophage through LPAR3/PI3K/AKT/mTOR signaling pathway. [PDF]

Biomark Res
He Y, Huang Y, Wang L, Hao S, Wang X, Han M, Zhou K, Xuan L, Ju M.   +8 more
europepmc   +1 more source

Inflammation and Immune Dysregulation Across Respiratory Diseases: From Cellular Mechanisms to Therapeutic Targets. [PDF]

J Inflamm Res
Kumar A, Silveyra P.
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Recent understanding of immunometabolic remodeling in pulmonary macrophages: homeostasis, chronic respiratory diseases, and therapeutic targeting. [PDF]

Front Pharmacol
Yuan Z, Alhaskawi A, Tang Y, Ruan B.
europepmc   +1 more source

Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis

Interdisciplinary Medicine, EarlyView.
Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar, Sunil Kumar Singh, Piush Srivastava, Sowdhamini Mahendiran, Rakesh Sathish Nair, Harsh Vyas, Saket Jha, Niraj Nag, Navin Viswakarma, Hitesh Kapoor, Swathi Suresh, Periannan Sethupathi, Sang‐Ging Ong, Jerrold S. Levine, Suman Setty, Mathayan Manikannan, Bellur S. Prabhakar, Basabi Rana, Ajay Rana   +18 more
wiley   +1 more source

Targeting the immune-metabolic axis reverses orthodontics-induced systemic pathology. [PDF]

Signal Transduct Target Ther
Zhang Y, Jiang S, Zheng H, Liu J, Heng BC, Li W, Han B, Lu D, Wei Y, Deng X.   +9 more
europepmc   +1 more source

Protective Role of Polydatin Against Vancomycin‐Induced Lung Toxicity via Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Ferroptosis Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez, Sefa Küçükler, Selim Çomaklı, Hasan Şimşek, Özge Kandemir, Fatih Mehmet Kandemir, Şaban Maraşlı   +6 more
wiley   +1 more source

Shared and niche-specific transcriptional signatures of macrophage aging revealed by a cross-tissue meta-analysis. [PDF]

BMC Biol
Schwab E, Tewelde E, Chen L, Benayoun BA.   +3 more
europepmc   +1 more source