Results 241 to 250 of about 183,665 (310)

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, EarlyView.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source

Significant but Temporary Efficacy of Statin for a Patient With Severe Autoimmune Pulmonary Alveolar Proteinosis: A Case Report. [PDF]

Respirol Case Rep
Makino F, Shibayama K, Muto Y, Hayakawa R, Izumi K, Suzuki Y, Nagashima O, Sasaki S, Takahashi K.   +8 more
europepmc   +1 more source

The scale matters: A review on stimuli‐responsive microrobots categorized by scale for biomedical applications

Responsive Materials, EarlyView.
We systematically summarize how each scale dictates fundamental choices in design feature, manufacturing technology, driving mechanism, and control strategy, which are inherently governed by scale‐dominated physical principles. Furthermore, the application of scale‐determined operation modes of microrobots across different stages of medical ...
Hang Yin, Yujing Li, Guanghao Wu, Yubing Guo   +3 more
wiley   +1 more source

Attenuating pulmonary injury and inflammation with C5/CD14 inhibition therapy: results from a porcine polytrauma model with blunt chest trauma. [PDF]

Eur J Trauma Emerg Surg
Mert Ü, Groven RVM, Qin K, Greven J, Balmayor ER, Mollnes TE, Huber-Lang M, van Griensven M, Hildebrand F, Horst K.   +9 more
europepmc   +1 more source

Assessing the Health Impacts of Contaminants on Green Turtles (Chelonia mydas) Along the Southern Coast of Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Chemical pollutants pose a significant threat to marine ecosystems. Among these contaminants are trace elements and polycyclic aromatic hydrocarbons (PAH). Green turtles can be employed to evaluate the oceans' health due to their coastal habitats and exposure to multiple threats.
Camila Roberta da Silva Ribeiro, Andressa Maria Rorato Nascimento de Matos, Eloiza Teles Caldart, Liana Rosa, Camila Domit, Guilherme dos Santos Lima, Ana Paula Frederico Rodrigues Loureiro Bracarense   +6 more
wiley   +1 more source

A microbiota-dependent bile acid reprograms alveolar macrophages to control lung inflammation. [PDF]

Signal Transduct Target Ther
Wolska M, Rodríguez-Viso P, Świątkowska A, Bulanda E, Wypych TP.   +4 more
europepmc   +1 more source

Variation on Toxic and Inflammatory Potential of Coal Smoke of Different Sources From a Region With High Lung Cancer Risk

Environmental Toxicology, EarlyView.
ABSTRACT Excess lung cancer risk in Xuanwei and Fuyuan, China, has been attributed to household air pollution from use of a locally sourced smoky (bituminous) coal. However, the carcinogenic mechanisms remain unclear. Given the important role of inflammation in lung cancer development, this study compared the proinflammatory potentials of the ...
Yongliang Zhang, Wei Hu, Nathanial Rothman, Dingyu Liu, Jihua Li, Jun Xu, Bofu Ning, Roel Vermeulen, Qing Lan, Flemming R. Cassee, George S. Downward   +10 more
wiley   +1 more source

Mitochondria-Dependent Metabolic Reprogramming Enhances Myofibroblast Differentiation and Aggravates Bleomycin-Induced Pulmonary Fibrosis. [PDF]

Cells
Yazaki K, Matsuno Y, Yabuuchi Y, Matsumura S, Kuramoto K, Yoshida K, Matsuyama M, Kiwamoto T, Morishima Y, Ishii Y, Ishikawa K, Nakada K, Hizawa N.   +12 more
europepmc   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

The Pneumoconiosis Renaissance: Revisiting the Pulmonary Pathology of Poorly Soluble Low Toxicity Particles: Insights from Rodent Inhalation Studies on Titanium Dioxide Nanoparticles. [PDF]

Nanomaterials (Basel)
Yamano S, Schaudien D, Umeda Y.
europepmc   +1 more source