Results 91 to 100 of about 1,368,417 (273)

Dynamic Function and Composition Changes of Immune Cells During Normal and Pathological Pregnancy at the Maternal-Fetal Interface

open access: yesFrontiers in Immunology, 2019
A successful pregnancy requires a fine-tuned and highly regulated balance between immune activation and embryonic antigen tolerance. Since the fetus is semi-allogeneic, the maternal immune system should exert tolerant to the fetus while maintaining the ...
Fenglian Yang   +2 more
doaj   +1 more source

Modelling the inflammatory process in atherosclerosis: a nonlinear renewal equation [PDF]

open access: yesarXiv, 2017
We present here a population structured model to describe the dynamics of macrophage cells. The model involves the interactions between modified LDL, monocytes/macrophages, cytokines and foam cells. The key assumption is that the individual macrophage dynamics depends on the amount of lipoproteins it has internalized.
arxiv  

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis

open access: yesCirculation Research, 2018
Rationale: It is assumed that atherosclerotic arteries contain several macrophage subsets endowed with specific functions. The precise identity of these subsets is poorly characterized as they have been defined by the expression of a restricted number of
C. Cochain   +8 more
semanticscholar   +1 more source

Modelling Erythroblastic Islands: Using a Hybrid Model to Assess the Function of Central Macrophage [PDF]

open access: yesarXiv, 2011
The production and regulation of red blood cells, erythropoiesis, occurs in the bone marrow where erythroid cells proliferate and differentiate within particular structures, called erythroblastic islands. A typical structure of these islands consists in a macrophage (white cell) surrounded by immature erythroid cells (progenitors), with more mature ...
arxiv  

Leukocyte Heparanase: A Double-Edged Sword in Tumor Progression

open access: yesFrontiers in Oncology, 2019
Heparanase is a β-D-endoglucuronidase that cleaves heparan sulfate, a complex glycosaminoglycan found ubiquitously throughout mammalian cells and tissues.
Alyce J. Mayfosh   +3 more
doaj   +1 more source

Deacylcynaropicrin Inhibits RANKL-Induced Osteoclastogenesis by Inhibiting NF-κB and MAPK and Promoting M2 Polarization of Macrophages

open access: yesFrontiers in Pharmacology, 2019
Inflammation can promote the maturity of osteoclasts and bone resorption in many bone disease such as osteoporosis and arthritis. Here, we aimed to investigate the inhibitory effects of deacylcynaropicrin (DAC) on osteoclastogenesis and bone resorption ...
Zhikun Li   +5 more
doaj   +1 more source

The Remarkable Plasticity of Macrophages: A Chance to Fight Cancer

open access: yesFrontiers in Immunology, 2019
It is well established that tumor-associated macrophages (TAM) found in most advanced tumors have a pro-tumoral role. In this context, TAM limit the activity of tumor-infiltrating lymphocytes (TIL), and a number of mechanisms have been described ...
Nadège Bercovici   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy