Results 181 to 190 of about 895,246 (248)

Mechanobiologically Engineered Mimicry of Extracellular Vesicles for Improved Systemic Biodistribution and Anti‐Inflammatory Treatment Efficacy in Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
Triblock copolymer‐reinforced liposomal mimics of extracellular vesicles are engineered with tunable membrane elasticity. A semi‐elastic formulation (Tri‐ARTEX8:2) co‐encapsulating stem cell cytosolic extract and AntagomiR155 targets inflamed joints via the ELVIS effect, reprograms macrophages from M1 to M2, and markedly alleviates collagen‐induced ...
Dahwun Kim, Hwira Baek, Su Yeon Lim, Min Sang Lee, Siyan Lyu, Jihyun Lee, Tun Naw Sut, Marta Gonçalves, Jeong Yi Kang, Joshua A. Jackman, Jin Woong Kim, Ji Hoon Jeong   +11 more
wiley   +1 more source

Inhibition of ferroptosis in inflammatory macrophages alleviates intestinal injury in neonatal necrotizing enterocolitis. [PDF]

Cell Death Discov
Shen L, Chen J, Tou J.
europepmc   +1 more source

A Study on the Phagocytosis of Macrophage

, 1969
Kensuke Ozu
openalex   +2 more sources

Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction

Advanced Healthcare Materials, EarlyView.
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li, Adriana‐Monica Radu, Azadeh Rezaei, Joel Turner, Kaveh Shakib, Akiko Obata, Toshihiro Kasuga, Gavin Jell   +7 more
wiley   +1 more source

Increased CD163+ Macrophage Activation and High Expression of CD163 Promote Granulosa Cell Apoptosis in Polycystic Ovary Syndrome. [PDF]

J Inflamm Res
Ye J, Wang S, Wang Z, Jiang Y, Jia J, Yang Y, Huo L, Liu X, Zhou Y, Yang Z, Mao J, Ma Y, Wang X.   +12 more
europepmc   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Extracellular vesicles from ovarian cancer cells induce senescent lipid-laden macrophages to facilitate omental metastasis. [PDF]

J Nanobiotechnology
Li G, Zhou X, Li W, Wu Q, Liu T, Huang L, Liu X, Zhao J, Xu X, Xu L, Wang Z, Gong L, Cai L, Cai J.   +13 more
europepmc   +1 more source

Interstitial N‐Strengthened Copper‐Based Bioactive Conductive Dressings Combined with Electromagnetic Fields for Enhanced Wound Healing

Advanced Healthcare Materials, EarlyView.
This study developed a nitrogen‐strengthened copper‐iron‐zinc (N‐CuFeZn) alloy bioactive dressing integrated with electromagnetic stimulation. The coaxial dressing, made from 0.04 mm filaments with 1120 MPa tensile strength, showed that electromagnetic activation enhanced therapeutic outcomes by increasing VEGF expression, promoting angiogenesis (2.1 ...
Xiaohui Qiu, Xianrui Wu, Shaohua Wang, Jie Gu, Senhao Ying, Jiaohao Mo, Chen Jing, Huiliang Cao, Zhongchang Wang, Jianda Zhou   +9 more
wiley   +1 more source

Patient-derived ovarian cancer models demonstrate the influence of tumor-associated macrophages on therapeutic response. [PDF]

Oncoimmunology
Nikeghbal P, Burke D, Armijo D, Aldarondo-Quiñones S, Lidke DS, Steinkamp MP.   +5 more
europepmc   +1 more source

Guided Bone Regeneration Membrane Materials Loaded with Chimeric Nanovesicles Promote Early Bone Defect Regeneration

Advanced Healthcare Materials, EarlyView.
Early bone regeneration is challenged by poor osteogenic microenvironments. We developed a novel guided bone regeneration (GBR) membrane: a plasma‐treated polycaprolactone (PT‐PCL) electrospun nanofiber functionalized with ultrasound sequentially extruded stromal vascular fraction chimeric vesicles (USE‐SCNVs). USE‐SCNVs require less equipment, enhance
Yufan Zhang, Yaqiong Wang, Xiaona Ning, Guichu Yue, Wenhui Zhang, Yicheng Chen, Xuelian Jia, Yu Zhang, Xiao Zhang, Zihan Lu, Simin Zhu, Fuwei Liu, Yong Zhao, Liang Kong   +13 more
wiley   +1 more source