Results 31 to 40 of about 1,818,468 (377)

Targeting macrophages in cancer immunotherapy

open access: yesSignal Transduction and Targeted Therapy, 2021
Immunotherapy is regarded as the most promising treatment for cancers. Various cancer immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies, immune checkpoint inhibitors, and small-molecule inhibitors, have achieved ...
Z. Duan, Yunping Luo
semanticscholar   +1 more source

Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes

open access: yesDisease Models & Mechanisms, 2017
Alphaviruses, such as chikungunya virus (CHIKV) and Sindbis virus (SINV), are vector-borne pathogens that cause acute illnesses in humans and are sometimes associated with neuropathies, especially in infants and elderly patients.
Gabriella Passoni   +12 more
doaj   +1 more source

Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis [PDF]

open access: yes, 2012
Current macrophage phenotype classifications are based on distinct in vitro culture conditions that do not adequately mirror complex tissue environments.
Weidenbusch, Marc, Anders, Hans-Joachim
core   +3 more sources

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

open access: yesJournal of Clinical Investigation, 1998
Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue remodeling, regulation of the immune response, or resolution of inflammation.
V. Fadok   +5 more
semanticscholar   +1 more source

Effects of Scutellariae Radix-acupuncture solution On Anti-inflammatory in RAW 264.7 macrophages

open access: yesJournal of Pharmacopuncture, 2003
Objective : Recently, Herbal-acupuncture therapeutics has been used for the treatment of inflammatory diseases such as rheumatoid arthritis. Especially, we have been interested in chemical mediators concerned with inflammation such as prostaglandin ...
Young-kwang Choi   +5 more
doaj   +1 more source

The Peculiar Characteristics of Fish Type I Interferons

open access: yesViruses, 2016
Antiviral type I interferons (IFNs) have been discovered in fish. Genomic studies revealed their considerable number in many species; some genes encode secreted and non-secreted isoforms.
Pierre Boudinot   +3 more
doaj   +1 more source

Effect of Imiquimod on Tachyzoites of Toxoplasma gondii and Infected Macrophages in vitro and in BALB/c Mice

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Treatment for toxoplasmosis is not completely successful because of their unwanted side effects, and new treatments are needed. Imiquimod has ability to moderate immune response and used to treat a wide variety of infections and tumors.
Leila Zaki   +4 more
doaj   +1 more source

Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages [PDF]

open access: yes, 2010
Background Interleukin-33 is a member of the IL-1 cytokine family whose functions are mediated and modulated by the ST2 receptor. IL-33-ST2 expression and interactions have been explored in mouse macrophages but little is known about the effect of IL-33 ...
Das, Anuk   +7 more
core   +5 more sources

Calcium phosphate: a substitute for aluminum adjuvants?

open access: yesExpert Review of Vaccines, 2017
Introduction: Calcium phosphate was used as an adjuvant in France in diphtheria, tetanus, pertussis and poliomyelitis vaccines. It was later completely substituted by alum salts in the late 80’s, but it still remains as an approved adjuvant for the World
Jean-Daniel Masson   +3 more
doaj   +1 more source

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