Results 31 to 40 of about 1,368,417 (273)
New insights into M1/M2 macrophages: key modulators in cancer progression
Cancer Cell International, 2021 Infiltration of macrophages in and around tumor nest represents one of the most crucial hallmarks during tumor progression. The mutual interactions with tumor cells and stromal microenvironment contribute to phenotypically polarization of tumor ...
Jiuyang Liu +3 more
semanticscholar +1 more source
Journal of Clinical Investigation, 1998 Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue remodeling, regulation of the immune response, or resolution of inflammation.
V. Fadok +5 more
semanticscholar +1 more source
Targeting macrophages in cancer immunotherapy
Signal Transduction and Targeted Therapy, 2021 Immunotherapy is regarded as the most promising treatment for cancers. Various cancer immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies, immune checkpoint inhibitors, and small-molecule inhibitors, have achieved ...
Z. Duan, Yunping Luo
semanticscholar +1 more source
Effects of Scutellariae Radix-acupuncture solution On Anti-inflammatory in RAW 264.7 macrophages
Journal of Pharmacopuncture, 2003 Objective : Recently, Herbal-acupuncture therapeutics has been used for the treatment of inflammatory diseases such as rheumatoid arthritis. Especially, we have been interested in chemical mediators concerned with inflammation such as prostaglandin ...
Young-kwang Choi +5 more
doaj +1 more source
The Peculiar Characteristics of Fish Type I Interferons
Viruses, 2016 Antiviral type I interferons (IFNs) have been discovered in fish. Genomic studies revealed their considerable number in many species; some genes encode secreted and non-secreted isoforms.
Pierre Boudinot +3 more
doaj +1 more source
Calcium phosphate: a substitute for aluminum adjuvants?
Expert Review of Vaccines, 2017 Introduction: Calcium phosphate was used as an adjuvant in France in diphtheria, tetanus, pertussis and poliomyelitis vaccines. It was later completely substituted by alum salts in the late 80’s, but it still remains as an approved adjuvant for the World
Jean-Daniel Masson +3 more
doaj +1 more source
The in silico macrophage: toward a better understanding of inflammatory disease [PDF]
Genome Medicine 2011, 3:4 (22 January 2011), 2011 Macrophages function as sentinel, cell-regulatory hubs capable of initiating, perpetuating and contributing to the resolution of an inflammatory response, following their activation from a resting state. Highly complex and varied gene expression programs within the macrophage enable such functional diversity.
arxiv +1 more source
Frontiers in Immunology, 2019 Macrophages are found in tissues, body cavities, and mucosal surfaces. Most tissue macrophages are seeded in the early embryo before definitive hematopoiesis is established. Others are derived from blood monocytes.
Marco Orecchioni +3 more
semanticscholar +1 more source
Macrophages in xenotransplantation [PDF]
Korean Journal of Transplantation, 2019 Xenotransplantation refers to organ transplantation across species. Immune rejection of xenografts is stronger and faster than that of allografts because of significant molecular differences between species. Recent studies have revealed the involvement of macrophages in xenograft and allograft rejections.
openaire +4 more sources
A new lipid-structured model to investigate the opposing effects of LDL and HDL on atherosclerotic plaque macrophages [PDF]
arXiv, 2022 Atherosclerotic plaques form in artery walls due to a chronic inflammatory response driven by lipid accumulation. A key component of the inflammatory response is the interaction between monocyte-derived macrophages and extracellular lipid. Although concentrations of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles in the blood
arxiv