Results 61 to 70 of about 1,368,417 (273)

Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages

open access: yesCell Communication and Signaling, 2018
. Background Macrophages are one of the most important players in the tumor microenvironment. The polarization status of tumor associated macrophages into a pro-inflammatory type M1 or anti-inflammatory type M2 may influence cancer progression and ...
Ineta Popēna   +9 more
doaj   +1 more source

Rifampicin-Loaded Mesoporous Silica Nanoparticles for the Treatment of Intracellular Infections

open access: yesAntibiotics, 2019
Infectious diseases remain a major burden in today’s world, causing high mortality rates and significant economic losses, with >9 million deaths per year predicted by 2030.
Santhni Subramaniam   +5 more
doaj   +1 more source

Engineering Immunomodulatory Biomaterials for Regenerating the Infarcted Myocardium

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Coronary artery disease is a severe ischemic condition characterized by the reduction of blood flow in the arteries of the heart that results in the dysfunction and death of cardiac tissue. Despite research over several decades on how to reduce long-term
Nora Bloise   +9 more
doaj   +1 more source

Podoplanin Positive Myeloid Cells Promote Glioma Development by Immune Suppression

open access: yesFrontiers in Oncology, 2019
The dynamic and interactive tumor microenvironment is conceived as a considerable parameter in tumor development and therapy response. Implementing this knowledge in the development of future cancer treatments could provide novel options in the combat of
Tanja Eisemann   +6 more
doaj   +1 more source

Dynamical Model of Mild Atherosclerosis: Applied Mathematical Aspects [PDF]

open access: yesarXiv, 2022
Atherosclerosis is a chronic inflammatory disease occurs due to plaque accumulation in the inner artery wall. In atherosclerotic plaque formation monocytes and macrophages play a significant role in controlling the disease dynamics. In the present article, the entire biochemical process of atherosclerotic plaque formation is presented in terms of an ...
arxiv  

Tumor-Associated Macrophages: Recent Insights and Therapies

open access: yesFrontiers in Oncology, 2020
Macrophages, which have functions of engulfing and digesting foreign substances, can clear away harmful matter, including cellular debris and tumor cells.
Jiawei Zhou   +5 more
semanticscholar   +1 more source

Macrophages in Marseille [PDF]

open access: yesImmunity, 2013
Immunology has recently witnessed several new developments in understanding the biology of macrophages. These exciting developments were the focus of a conference in Marseille, France, in January 2013. This conference is summarized here.
openaire   +2 more sources

Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo

open access: yesFrontiers in Immunology, 2017
Outer membrane vesicles (OMVs) are proteoliposomes blebbed from the surface of Gram-negative bacteria. Chronic periodontitis is associated with an increase in subgingival plaque of Gram-negative bacteria, Porphyromonas gingivalis, Treponema denticola ...
Jessica D. Cecil   +7 more
doaj   +1 more source

Molecular responses of mouse macrophages to copper and copper oxide nanoparticles inferred from proteomic analyses [PDF]

open access: yesMol Cell Proteomics 12, 11 (2013) 3108-22, 2013
The molecular responses of macrophages to copper-based nanoparticles have been investigated via a combination of proteomic and biochemical approaches, using the RAW264.7 cell line as a model. Both metallic copper and copper oxide nanoparticles have been tested, with copper ion and zirconium oxide nanoparticles used as controls.
arxiv   +1 more source

Epigenomics of macrophages [PDF]

open access: yesImmunological Reviews, 2014
SummaryMacrophages play essential roles in tissue homeostasis, pathogen elimination, and tissue repair. A defining characteristic of these cells is their ability to efficiently adapt to a variety of abruptly changing and complex environments. This ability is intrinsically linked to a capacity to quickly alter their transcriptome, and this is tightly ...
Christopher K. Glass, David Gosselin
openaire   +2 more sources

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