Results 61 to 70 of about 895,246 (248)
Production of Interferon by Alveolar Macrophages [PDF]
Jean D. Acton, Quentin N. Myrvik
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Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
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Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla+13 more
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Ca++-Dependent Binding of Antigen-19 S Antibody Complexes to Macrophages [PDF]
Waltraut H. Lay, Victor Nussenzweig
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The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
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A Role of Macrophages in the Stimulation of Immune Responses by Adjuvants [PDF]
Emil R. Unanue+2 more
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HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang+6 more
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Growth of Mycobacterium lepraemurium in Cultures of Mouse Peritoneal Macrophages [PDF]
Y. T. Chang, R N Andersen, Z. Vaituzis
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In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins+2 more
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OBSERVATIONS ON MACROPHAGE BEHAVIOR IN THE FIN OF XENOPUS LARVAE
H. E. Lehman
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