Results 61 to 70 of about 1,971,731 (404)
From Species to Regional and Local Specialization of Intestinal Macrophages
Initially intended for nutrient uptake, phagocytosis represents a central mechanism of debris removal and host defense against invading pathogens through the entire animal kingdom. In vertebrates and also many invertebrates, macrophages (MFs) and MF-like
Cynthia Arroyo Portilla+4 more
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Macrophages expressing PPARγ support skeletal muscle regeneration by inducing secretion of the myoblast growth factor GDF3.
openaire +3 more sources
Macrophages are found in tissues, body cavities, and mucosal surfaces. Most tissue macrophages are seeded in the early embryo before definitive hematopoiesis is established. Others are derived from blood monocytes.
Marco Orecchioni+3 more
semanticscholar +1 more source
Currently, inflammatory bowel disease (IBD) is a serious public health problem on the rise worldwide. In this work, we utilized the zebrafish to introduce a new model of intestinal inflammation triggered by food intake.
Maximo Coronado+5 more
doaj +1 more source
Macrophages in Lung Injury, Repair, and Fibrosis
Fibrosis progression in the lung commonly results in impaired functional gas exchange, respiratory failure, or even death. In addition to the aberrant activation and differentiation of lung fibroblasts, persistent alveolar injury and incomplete repair ...
Peiyong Cheng+2 more
semanticscholar +1 more source
The pulmonary macrophage. [PDF]
An overview of the pulmonary macrophage is provided, with particular emphasis on the origin of this cell and the adaptive mechanisms whereby the macrophagic system is able to respond to increased inhalant loads of organic and inorganic pollutants. Evidence is presented which favors an hematopoietic origin for the alveolar macrophage with a monocytic ...
openaire +2 more sources
Idiopathic pulmonary fibrosis (IPF) is serious chronic lung disease with limited therapeutic approaches. Inflammation and immune disorders are considered as the main factors in the initiation and development of pulmonary fibrosis.
Xiaoqing Sang+14 more
doaj +1 more source
Macrophages: The Good, the Bad, and the Gluttony
Macrophages are dynamic cells that play critical roles in the induction and resolution of sterile inflammation. In this review, we will compile and interpret recent findings on the plasticity of macrophages and how these cells contribute to the ...
E. Ross, A. Devitt, Jill R. Johnson
semanticscholar +1 more source
Vascular Macrophages as Therapeutic Targets to Treat Intracranial Aneurysms
Aneurysmal subarachnoid hemorrhage (aSAH) is a highly fatal and morbid type of hemorrhagic strokes. Intracranial aneurysms (ICAs) rupture cause subarachnoid hemorrhage.
Sajjad Muhammad+7 more
doaj +1 more source
Enhancing Cystic Fibrosis Immune Regulation
In cystic fibrosis (CF), sustained infection and exuberant inflammation results in debilitating and often fatal lung disease. Advancement in CF therapeutics has provided successful treatment regimens for a variety of clinical consequences in CF; however ...
Anna M. van Heeckeren+19 more
doaj +1 more source