Results 71 to 80 of about 1,368,417 (273)
Cell Reports, 2017 The unprecedented 2013–2016 outbreak of Ebola virus (EBOV) resulted in over 11,300 human deaths. Host resistance to RNA viruses requires RIG-I-like receptor (RLR) signaling through the adaptor protein, mitochondrial antiviral signaling protein (MAVS ...
Mukta Dutta +14 more
doaj +1 more source
In silico prediction of protein-protein interactions in human macrophages [PDF]
BMC Research Notes, BioMed Central, 2014, 7, pp.157, 2015 Background: Protein-protein interaction (PPI) network analyses are highly valuable in deciphering and understanding the intricate organisation of cellular functions. Nevertheless, the majority of available protein-protein interaction networks are context-less, i.e.
arxiv +1 more source
Frontiers in Immunology, 2018 Since the seminal discovery of dendritic cells (DCs) by Steinman and Cohn in 1973, there has been an ongoing debate to what extent macrophages and DCs are related and perform different functions.
Joanna Grabowska +3 more
doaj +1 more source
Babesia microti Confers Macrophage-Based Cross-Protective Immunity Against Murine Malaria
Frontiers in Cellular and Infection Microbiology, 2020 Malaria and babesiosis, the two primary intraerythrocytic protozoan diseases of humans, have been reported in multiple cases of co-infection in endemic regions.
Artemis Efstratiou +18 more
doaj +1 more source
Nature Communications, 2020 Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG).
Xiaobing Yu +8 more
semanticscholar +1 more source
Frontiers in Immunology, 2020 Cyclic di-AMP (c-di-AMP) is an important signaling molecule for pneumococci, and as a uniquely prokaryotic product it can be recognized by mammalian cells as a danger signal that triggers innate immunity.
Alicia K. Wooten +18 more
doaj +1 more source
A chemotaxis reaction-diffusion model for Multiple Sclerosis with Allee effect [PDF]
arXiv, 2023 In this paper, we study a modification of the mathematical model describing inflammation and demyelination patterns in the brain caused by Multiple Sclerosis proposed in [Lombardo et al. (2017), Journal of Mathematical Biology, 75, 373--417]. In particular, we hypothesize a minimal amount of macrophages to be able to start and sustain the inflammatory ...
arxiv
Estimating the number of tissue resident macrophages [PDF]
arXiv, 2016 I provide a simple estimation for the number of macrophages in a tissue, arising from the hypothesis that they should keep infections below a certain threshold, above which neutrophils are recruited from blood circulation. The estimation reads Nm=a Ncel^{\alpha}/Nmax, where a is a numerical coefficient, the exponent {\alpha} is near 2/3, and Nmax is ...
arxiv
ACTIVATION OF CYTOTOXIC MACROPHAGE WITH MACROPHAGE
The KITAKANTO Medical Journal, 1978 Mouse peritoneal exudate macrophages induced by peptone (macrophages) were activated with a lymphokine, macrophage activating factor (MAF), and became cytotoxic against various tumor cells. Peritoneal resident adherent-cells from normal mice were not activated with MAF.When macrophages were incubated with aggregated human immunoglobulin G (agg-HGG) for
openaire +3 more sources
Macrophage Heterogeneity [PDF]
Vox Sanguinis, 1979 Abstract. Macrophages are a mobile, functionally diverse group of cells which may be recruited and stimulated to a high degree of metabolic activity. Heterogeneity may be detected from one site to another and result from local influences, e.g. lung v.
K E, Hopper, P R, Wood, D S, Nelson
openaire +2 more sources