Results 81 to 90 of about 1,971,731 (404)

Case Report: Dendritic Cells and Macrophages Capture Sperm in Chronically Inflamed Human Epididymis

Frontiers in Immunology, 2021
Chronic inflammation of the male genital tract is thought to be a primary etiological factor of male infertility. The abundance and activation of macrophages and dendritic cells in patients with chronic inflammation of genital tract were closely ...
Wenzhong Zheng, Shiqiang Zhang, Xiaobao Chen, Shaoqin Jiang, Zhihao Li, Mengqiang Li   +5 more
doaj   +1 more source

Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages [PDF]

, 2018
Background: As crucial regulators of the immune response against pathogens, macrophages have been extensively shown also to be important players in several diseases, including cancer. Specifically, breast cancer macrophages tightly control the angiogenic
Blandino, Giovanni, Donzelli, Sara, Fazi, Francesco, Fontemaggi, Giulia, Gallo, Enzo, Iosue, Ilaria, Masciarelli, Silvia, Melucci, Elisa, Milano, Elisa, Mottolese, Marcella, Pruszko, Magdalena, Sacconi, Andrea, Terrenato, Irene, Zylicz, Alicja, Zylicz, Maciej   +14 more
core   +3 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Identification of Long Non-coding RNA Isolated From Naturally Infected Macrophages and Associated With Bovine Johne's Disease in Canadian Holstein Using a Combination of Neural Networks and Logistic Regression

Frontiers in Veterinary Science, 2021
Mycobacterium avium ssp. paratuberculosis (MAP) causes chronic enteritis in most ruminants. The pathogen MAP causes Johne's disease (JD), a chronic, incurable, wasting disease. Weight loss, diarrhea, and a gradual drop in milk production characterize the
Andrew Marete, Olivier Ariel, Olivier Ariel, Eveline Ibeagha-Awemu, Nathalie Bissonnette   +4 more
doaj   +1 more source

The Biology of Macrophages

, 2014
Macrophages are part of the innate immune system, recognizing, engulfing, and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi, and helminths. The destructive potential of macrophages and their ability to secrete regulators of the function of neighboring cells contribute to many aspects of homeostasis.
Sasmono, R.T., Hume, D. A.
openaire   +3 more sources

Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages [PDF]

, 2010
Background Interleukin-33 is a member of the IL-1 cytokine family whose functions are mediated and modulated by the ST2 receptor. IL-33-ST2 expression and interactions have been explored in mouse macrophages but little is known about the effect of IL-33 ...
Das, Anuk, Duffy, Karen E, Finn, William G., Hartigan, Adam Joseph, Hogaboam, Cory M., Joshi, Amrita D., Kunkel, Steven L., Oak, Sameer R   +7 more
core   +5 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Epigenomics of macrophages [PDF]

Immunological Reviews, 2014
SummaryMacrophages play essential roles in tissue homeostasis, pathogen elimination, and tissue repair. A defining characteristic of these cells is their ability to efficiently adapt to a variety of abruptly changing and complex environments. This ability is intrinsically linked to a capacity to quickly alter their transcriptome, and this is tightly ...
Christopher K. Glass, David Gosselin
openaire   +2 more sources

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages.

Journal of Immunology, 1992
During normal tissue remodeling, macrophages remove unwanted cells, including those that have undergone programmed cell death, or apoptosis. This widespread process extends to the deletion of thymocytes (negative selection), in which cells expressing ...
V. Fadok, D. Voelker, P. Campbell, J. Cohen, D. Bratton, P. Henson   +5 more
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source