Results 81 to 90 of about 1,368,417 (273)

More Than Just Attractive: How CCL2 Influences Myeloid Cell Behavior Beyond Chemotaxis

open access: yesFrontiers in Immunology, 2019
Monocyte chemoattractant protein-1 (MCP-1/CCL2) is renowned for its ability to drive the chemotaxis of myeloid and lymphoid cells. It orchestrates the migration of these cell types both during physiological immune defense and in pathological ...
Martha Gschwandtner   +2 more
doaj   +1 more source

Mechanisms underlying of antiretroviral drugs in different cellular reservoirs with a focus on macrophages

open access: yesVirulence, 2020
Ongoing with current combinations of antiretroviral drugs for the treatment of Human Immunodeficiency Virus (HIV) infection can successfully maintain long-term suppression of HIV-1 replication in plasma.
Stefano Aquaro   +3 more
doaj   +1 more source

Effects of nanoparticles on murine macrophages [PDF]

open access: yes, 2011
Metallic nanoparticles are more and more widely used in an increasing number of applications. Consequently, they are more and more present in the environment, and the risk that they may represent for human health must be evaluated. This requires to increase our knowledge of the cellular responses to nanoparticles. In this context, macrophages appear as
arxiv   +1 more source

IL-10 inhibits cytokine production by activated macrophages.

open access: yesJournal of Immunology, 1991
IL-10 inhibits the ability of macrophage but not B cell APC to stimulate cytokine synthesis by Th1 T cell clones. In this study we have examined the direct effects of IL-10 on both macrophage cell lines and normal peritoneal macrophages.
D. Fiorentino   +4 more
semanticscholar   +1 more source

A replication-incompetent CD154/40L recombinant vaccinia virus induces direct and macrophage-mediated antitumor effects in vitro and in vivo

open access: yesOncoImmunology, 2019
CD40 triggering may result in antitumor effects of potentially high clinical relevance. To gain insights important for patient selection and to identify adequate targeting techniques, we investigated CD40 expression in human cancer tissues and generated ...
Valeria Governa   +9 more
doaj   +1 more source

Effects of Ox-LDL on Macrophages NAD(P)H Autofluorescence Changes by Two-photon Microscopy [PDF]

open access: yesDans European Nano Systems Worshop - ENS 2005, Paris : France (2005), 2007
Ox-LDL uptakes by macrophage play a critical role in the happening of atherosclerosis. Because of its low damage on observed cells and better signal-to- background ratio, two-photon excitation fluorescence microscopy is used to observe NAD(P)H autofluorescence of macrophage under difference cultured conditions- bare cover glass, coated with fibronectin
arxiv  

Trypanosoma brucei Secreted Aromatic Ketoacids Activate the Nrf2/HO-1 Pathway and Suppress Pro-inflammatory Responses in Primary Murine Glia and Macrophages

open access: yesFrontiers in Immunology, 2019
African trypanosomes, such as Trypanosoma brucei (T. brucei), are protozoan parasites of the mammalian vasculature and central nervous system that are best known for causing fatal human sleeping sickness.
Nicole K. Campbell   +7 more
doaj   +1 more source

The Biophysical Micro-Environment's Influence on Cell Fate Decisions During Macrophage Activation and Somatic Cell Reprogramming [PDF]

open access: yesarXiv, 2020
Cells are known to sense and respond to their mechanical microenvironment in profound ways. Various evidence has implicated the adhesome, a body of adhesion associated proteins, in several cell fate decisions, including differentiation and proliferation.
arxiv  

Extracellular Vesicles in Mycobacterial Infections: Their Potential as Molecule Transfer Vectors

open access: yesFrontiers in Immunology, 2019
Extracellular vesicles are membrane-bound structures released by living cells and present in body fluids. Their composition includes proteins, lipids, carbohydrates, and nucleic acids and are involved in transfers between cells.
Jianjun Wang   +3 more
doaj   +1 more source

Tumor-associated macrophages: an accomplice in solid tumor progression

open access: yesJournal of Biomedical Sciences, 2019
In many solid tumor types, tumor-associated macrophages (TAMs) are important components of the tumor microenvironment (TME). Moreover, TAMs infiltration is strongly associated with poor survival in solid tumor patients.
Yibing Chen   +5 more
semanticscholar   +1 more source

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