Macroprolactinemia in a young man and review of the literature [PDF]
A 21-year old man, complaining of headaches and fatigue, with a negative past medical history and a normal clinical examination, underwent a hormonal investigation which revealed hyper-prolactinemia and intact pituitary-gonadal axis. Drug-induced hyperprolactinemia was excluded. Pituitary magnetic resonance imaging indicated a microadenoma in the right
Evangeline Vassilatou+3 more
openalex +4 more sources
PCOS and Hyperprolactinemia: Conflicting Conditions or Comorbidities? [PDF]
Currently, hyperprolactinemia is considered as a condition to be excluded during the diagnosis of polycystic ovarian syndrome (PCOS), because it often demonstrates clinical signs similar to PCOS.
Alina V. Atalyan+4 more
doaj +1 more source
[Combination of macro-TSH and macroprolactinemia phenomena in a patient with autoimmune thyroiditis and vitiligo]. [PDF]
Sazonova DV+6 more
europepmc +3 more sources
Assessment of macroprolactinemia by polyethylene glycol precipitation method
AbstractBackgroundMacroprolactin is a molecule that results from association between monomeric prolactin (PRL) and immunoglobulin G (IgG). It has longer half-life and is considered biologically inactive, although it retains immunoreactivity, being detected in most available immunoassays.ObjectiveTo evaluate polyethylene glycol (PEG) precipitation ...
Ana Maia Silva+4 more
+5 more sources
Prolactin in headache and migraine: A systematic review of preclinical studies
Abstract Objective To systemically review preclinical studies investigating the implication of prolactin signaling in headache and migraine pathophysiology. Background The features of migraine attacks, including characteristics, duration, frequency, and prevalence, are sex‐dependent with variability across a lifetime, indicating the involvement of the ...
Mohammad Al‐Mahdi Al‐Karagholi+4 more
wiley +1 more source
Editorial: Is macroprolactinemia just a diagnostic pitfall? [PDF]
As hyperprolactinemia is involved in the impairment of the gonadotropic axis, serum prolactin (PRL) assessment is often required in the clinical scenario of menstrual disturbances, infertility, loss of libido, galactorrhea, osteoporosis, and bone fractures [1–3].
Marcello D. Bronstein
openalex +4 more sources
Macroprolactinemia: new insights in hyperprolactinemia [PDF]
Hypersecretion of prolactin by lactotroph cells of the anterior pituitary may lead to hyperprolactinemia in physiological, pathological and idiopathic conditions. Most patients with idiopathic hyperprolactinemia may have radiologically undetected microprolactinomas, but some may present other causes of hyperprolactinemia described as macroprolactinemia.
Vlatka Tomic+6 more
openaire +3 more sources
Association of Cadmium, Chromium, Manganese and Lead with Hyperprolactinemia: A Pilot Study [PDF]
Introduction: Hyperprolactinemia is one of the most common hypothalamic-pituitary dysfunctions where serum prolactin levels increase beyond normal range. Studies have suggested association of heavy metals with prolactin levels.
Amanpreet Kaur Kalsi+3 more
doaj +1 more source
PROLACTIN AND HYPERPROLACTINAEMIA IN FEMALE REPRODUCTIVE ENDOCRINOLOGY – AN UPDATE [PDF]
Hyperprolactinaemia is one of the most frequent causes of anovulation, resulting in infertility and hypoestrogenic state with consequences on overall women’s health.
Kutlešić, Ranko M.+5 more
core +1 more source
Cardiometabolic risk factors in young women with macroprolactinaemia [PDF]
Introduction: The predominance of high-molecular-weight forms of prolactin in plasma is referred to as macroprolactinaemia. Unlike monomeric hyperprolactinaemia, no previous study has investigated cardiometabolic risk factors in subjects with elevated ...
Krysiak, Robert+2 more
core +2 more sources