Results 31 to 40 of about 525,552 (330)

Neovascular Macular Degeneration: A Review of Etiology, Risk Factors, and Recent Advances in Research and Therapy

open access: yesInternational Journal of Molecular Sciences, 2021
Neovascular age-related macular degeneration (exudative or wet AMD) is a prevalent, progressive retinal degenerative macular disease that is characterized by neovascularization of the choroid, mainly affecting the elderly population causing gradual ...
Arunbalaji Pugazhendhi   +3 more
semanticscholar   +1 more source

Extracellular vesicles as a potential therapeutic for age-related macular degeneration

open access: yesNeural Regeneration Research, 2023
Age-related macular degeneration is a major global cause of central visual impairment and severe vision loss. With an aging population, the already immense economic burden of costly anti-vascular endothelial growth factor treatment is likely to increase.
Lorraine L. C. Chow, Ben Mead
doaj   +1 more source

Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]

open access: yes, 2017
Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson   +8 more
core   +1 more source

Subretinal fibrosis in neovascular age-related macular degeneration: current concepts, therapeutic avenues, and future perspectives

open access: yesCell and Tissue Research, 2021
Age-related macular degeneration (AMD) is a progressive, degenerative disease of the human retina which in its most aggressive form is associated with the formation of macular neovascularization (MNV) and subretinal fibrosis leading to irreversible ...
Louis Tenbrock   +7 more
semanticscholar   +1 more source

The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration

open access: yesClinics, 2011
OBJECTIVE: To investigate the role of oxidant/antioxidant status and protein oxidation in the development of age-related macular degeneration. METHOD: The activities of serum superoxide dismutase and glutathione peroxidase and the levels of serum ...
Zuhal Yildirim   +2 more
doaj   +1 more source

New Frontiers in Retina: highlights of the 2020 angiogenesis, exudation and degeneration symposium

open access: yesInternational Journal of Retina and Vitreous, 2020
We summarize the most important findings presented at the 2020 angiogenesis, exudation and degeneration symposium in five topic areas: (1) epidemiology of retinal vascular disease and macular degeneration; (2) dry AMD and geographic atrophy; (3 ...
Carmen A. Puliafito, Charles C. Wykoff
doaj   +1 more source

Distinguishing wet from dry age-related macular degeneration using three-dimensional computer-automated threshold Amsler grid testing [PDF]

open access: yes, 2011
Background/aims: With the increased efficacy of current therapy for wet age-related macular degeneration (AMD), better ways to detect wet AMD are needed.
Bababeygy, Simon R.   +5 more
core   +1 more source

Recent advances of exosomes in age-related macular degeneration

open access: yesFrontiers in Pharmacology, 2023
Exosomes are 30–150 nm extracellular vesicles that are secreted by almost all types of cells. Exosomes contain a variety of biologically active substances, such as proteins, nucleic acids, and lipids, and are important in the intercellular communication ...
Feng Gu, Jiyu Jiang, Peng Sun
doaj   +1 more source

Ranibizumab in neovascular age-related macular degeneration

open access: yesClinical Interventions in Aging, 2006
Neovascular age-related macular degeneration (AMD) is a visually devastating condition resulting from choroidal neovascularization and secondary photoreceptor loss.
K. Eng, P. Kertes
semanticscholar   +1 more source

Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration

open access: yesNeural Regeneration Research, 2020
The retina may suffer neurodegenerative damages, as other tissues of the central nervous system do, and serious eye diseases may develop. One of them is age-related macular degeneration, which causes progressive loss of vision due to retina degeneration.
Francisco Bosch-Morell   +9 more
doaj   +1 more source

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