Results 41 to 50 of about 525,552 (330)

Non-invasive testing for early detection of neovascular macular degeneration in unaffected second eyes of older adults: EDNA diagnostic accuracy study

open access: yesHealth Technology Assessment, 2022
Background: Neovascular age-related macular degeneration is a leading cause of sight loss, and early detection and treatment is important. For patients with neovascular age-related macular degeneration in one eye, it is usual practice to monitor the ...
Katie Banister   +11 more
doaj   +1 more source

Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review

open access: yesOftalʹmologiâ, 2023
Age related macular degeneration is a leading cause of vision loss and an increasing problem of disability throughout the world among adults. That revue covers historical points, risk factors, pathogenesis, classification and current treatment ways of ...
A. N. Kulikov   +2 more
doaj   +1 more source

Blindness incidence in Germany - A population-based study from Württemberg-Hohenzollern [PDF]

open access: yes, 1999
Few data on the incidence of blindness in Germany are available. We analysed causes of legal blindness for the region Württemberg-Hohenzollern (population 5.5 million) in order to help fill in this gap.
Klauss, V.   +4 more
core   +1 more source

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Optical Coherence Tomographic Angiography Imaging in Age-Related Macular Degeneration. [PDF]

open access: yes, 2017
Optical coherence tomographic angiography (OCTA) is emerging as a rapid, noninvasive imaging modality that can provide detailed structural and flow information on retinal and choroidal vasculature.
Desai, Ria   +5 more
core   +3 more sources

Age- and sex-based evaluation of the association between refractive error and age-related macular degeneration in the Korean population.

open access: yesPLoS ONE, 2020
PURPOSE:The aim of this study was to investigate the association between refractive error and prevalence of age-related macular degeneration (AMD) in Korean adults, based on the sex and age group.
Kook Lee   +4 more
doaj   +1 more source

Association of drusen deposition with choroidal intercapillary pillars in the aging human eye [PDF]

open access: yes, 2004
PURPOSE. To determine the pattern of drusen accumulation with age and to investigate the initial sites of deposition and their relationship to choroidal capillaries in human donor eyes from the eye bank of Moorfields Eye Hospital.METHODS.
Al Hosaini, H   +5 more
core   +1 more source

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

open access: yesNature Genetics, 2015
Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the elderly, with limited therapeutic options. Here we report on a study of >12 million variants, including 163,714 directly genotyped, mostly rare, protein-altering ...
F. Grassmann, Shritoma Sengupta
semanticscholar   +1 more source

EMT and EndMT: Emerging Roles in Age-Related Macular Degeneration

open access: yesInternational Journal of Molecular Sciences, 2020
Epithelial–mesenchymal transition (EMT) and endothelial–mesenchymal transition (EndMT) are physiological processes required for normal embryogenesis. However, these processes can be hijacked in pathological conditions to facilitate tissue fibrosis and ...
Daisy Y. Shu   +2 more
semanticscholar   +1 more source

Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review. [PDF]

open access: yes, 2019
As a part of the central nervous system, the retina may reflect both physiologic processes and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put forth to understand how Alzheimer's disease (AD) pathology may manifest
Honma, Patrick   +2 more
core   +1 more source

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