Results 61 to 70 of about 511,582 (401)
The Role of Inflammation in Age-Related Macular Degeneration
International Journal on Biological Sciences, 2020 Age-related macular degeneration (AMD) is a blinding eye disease which incidence gradually increases with age. Inflammation participates in AMD pathogenesis, including choroidal neovascularization and geographic atrophy.
Wei Tan +4 more
semanticscholar +1 more source
Depressive symptoms and quality of life in people with age-related macular degeneration [PDF]
, 2011 Purpose: To examine quality of life and associated factors in people with Age-Related Macular Degeneration (AMD). Methods: One hundred and forty-five AMD participants (mean age 78.0 +/- 7.7 years) and 104 age- and gender- matched controls (mean age 78.1 +
Mathew, Remy Sheena +5 more
core +1 more source
Peripapillary Intravitreal Injection Improves AAV-Mediated Retinal Transduction
Molecular Therapy: Methods & Clinical Development, 2020 The intravitreal (IVT) injection method is a choice when targeting the inner retina for gene therapy. However, the transduction efficiency of adeno-associated virus (AAV) vectors administered by the IVT route is usually low and may be affected by several
Sanjar Batirovich Madrakhimov +5 more
doaj
Widening use of dexamethasone implant for the treatment of macular edema [PDF]
, 2017 Sustained-release intravitreal 0.7 mg dexamethasone (DEX) implant is approved in Europe for the treatment of macular edema related to diabetic retinopathy, branch retinal vein occlusion, central retinal vein occlusion, and non-infectious uveitis.
Avitabile T. +9 more
core +2 more sources
JAMA ophthalmology, 2020 This randomized clinical trial evaluates extended dosing with faricimab in patients with neovascular age-related macular degeneration (nAMD).
A. Khanani +9 more
semanticscholar +1 more source
In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques. [PDF]
, 2017 Nonhuman primates are the only mammals to possess a true macula similar to humans, and spontaneously develop drusenoid lesions which are hallmarks of age-related macular degeneration (AMD).
Cunefare, David +8 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad +8 more
wiley +1 more source
Age-related macular degeneration: an overview
Revista Brasileira de Oftalmologia, 2021 Age-related macular degeneration is the most important cause of irreversible vision loss in the elderly and has been considered a severe public health problem. Current treatments have only been successful in delaying the loss of central vision.
Rogil José de Almeida Torres +1 more
doaj +1 more source
JAMA ophthalmology, 2021 This observational analysis assesses the effects of certain lifestyle risk factors on age-related macular degeneration.
Valerie Kuan +6 more
semanticscholar +1 more source
Factors associated with extended remission in neovascular age-related macular degeneration on pro re nata treatment protocol. [PDF]
, 2020 AimTo show the characteristics and outcomes of patients with neovascular age-related macular degeneration (nAMD) who had extended remission (ER) while on a pro re nata (PRN) treatment protocol.MethodsThis was a retrospective case-control study of a ...
Amador-Patarroyo, Manuel J +6 more
core