Results 81 to 90 of about 525,552 (330)

Blue-light filtering spectacle lenses for visual performance, sleep, and macular health in adults [PDF]

, 2019
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess whether blue-light filtering spectacle lenses impart effects on visual function, provide protection to the macula, or both.
Busija, L., Downie, L. E., Hull, C., Keller, P. R., Lawrenson, J. G.   +4 more
core   +1 more source

Cost-effectiveness analysis of brolucizumab versus aflibercept for the treatment of neovascular age-related macular degeneration (nAMD) in Italy [PDF]

, 2022
Nicola Ferrante, Daniela Ritrovato, Rossella Bitonti, Gianluca Furneri   +3 more
openalex   +1 more source

Photonic Nanomaterials for Wearable Health Solutions

Advanced Materials, EarlyView.
This review discusses the fundamentals and applications of photonic nanomaterials in wearable health technologies. It covers light‐matter interactions, synthesis, and functionalization strategies, device assembly, and sensing capabilities. Applications include skin patches and contact lenses for diagnostics and therapy. Future perspectives emphasize AI‐
Taewoong Park, Jung Woo Leem, Young L. Kim, Chi Hwan Lee   +3 more
wiley   +1 more source

Role of amyloid β-peptide in the pathogenesis of age-related macular degeneration

BMJ Open Ophthalmology, 2021
Age-related macular degeneration (AMD) is the most common eye disease in elderly patients, which could lead to irreversible vision loss and blindness. Increasing evidence indicates that amyloid β-peptide (Aβ) might be associated with the pathogenesis of ...
Jiantao Wang, Xinghuai Sun, Minwei Wang, Shiqi Su, Shaoyun Jiang   +4 more
doaj   +1 more source

Association of Systemic Inflammation With Retinal Vascular Caliber in Patients With AIDS. [PDF]

, 2019
PurposeTo evaluate relationships among retinal vascular caliber and biomarkers of systemic inflammation in patients with AIDS.MethodsA total of 454 participants with AIDS had retinal vascular caliber (central retinal artery equivalent and central retinal
Cheu, Ryan, Danis, Ronald P, Hunt, Peter W, Jabs, Douglas A, Jones, Norman, Klatt, Nichole R, Milush, Jeffrey M, Pak, Jeong Won, Trang, Garrett, Van Natta, Mark L   +9 more
core   +1 more source

Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance Alu elements, comprising more than 10% of the human genome, propagate via retrotransposition. This genomic expansion requires enzymatic activity of L1 that reverse transcribes Alu RNA into Alu cDNA in the nucleus.
S. Fukuda, Akhil Varshney, B. Fowler, Shao-bin Wang, S. Narendran, Kameshwari Ambati, T. Yasuma, J. Magagnoli, Hannah Leung, Shuichiro Hirahara, Yosuke Nagasaka, Reo Yasuma, Ivana Apicella, Felipe Pereira, R. Makin, Eamonn Magner, Xinan Liu, Jian Sun, Mo Wang, Kirstie L. Baker, Kenneth M. Marion, Xiwen Huang, E. Baghdasaryan, Meenakshi Ambati, Vidya L. Ambati, Akshat Pandey, Lekha Pandya, T. Cummings, Daipayan Banerjee, Peirong Huang, Praveen Yerramothu, G. Tolstonog, U. Held, Jennifer A. Erwin, A. Paquola, J. Herdy, Y. Ogura, H. Terasaki, T. Oshika, Shaban Darwish, Ramendra K. Singh, Saghar Mozaffari, Deepak Bhattarai, Kyung Bo Kim, J. Hardin, C. Bennett, D. Hinton, T. Hanson, C. Röver, K. Parang, N. Kerur, Jinze Liu, B. Werner, S. Sutton, S. Sadda, G. Schumann, Bradley D. Gelfand, F. Gage, J. Ambati   +58 more
semanticscholar   +1 more source

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

Advanced Science, EarlyView.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie, Yingjun Cai, Bolin Chen, Bowen Li, Jing Zou, Huizhuo Xu   +5 more
wiley   +1 more source

Fluorescein angiography compared to three-dimensional measurements by the retinal thickness analyzer in classic choroidal neovascularization [PDF]

, 2007
Purpose: To compare and correlate imaging of classic subfoveal choroidal neovascularization (CNV) with noninvasive 3-dimensional imaging by the retinal thickness analyzer (RTA) to conventional fluorescein angiography (FA).
Kampik, Anselm, Neubauer, A. S., Rombold, F., Strauss, R. W.   +3 more
core   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

Intravitreal Administration of Human Bone Marrow CD34+ Stem Cells in a Murine Model of Retinal Degeneration. [PDF]

, 2016
PurposeIntravitreal murine lineage-negative bone marrow (BM) hematopoietic cells slow down retinal degeneration. Because human BM CD34+ hematopoietic cells are not precisely comparable to murine cells, this study examined the effect of intravitreal human
Annett, Geralyn, Cary, Whitney, Moisseiev, Elad, Motta, Monica, Murphy, Christopher J, Nolta, Jan A, Oltjen, Sharon, Park, Susanna S, Smit-McBride, Zeljka, Zawadzki, Robert J, Zhang, Pengfei   +10 more
core   +2 more sources