Results 181 to 190 of about 20,289 (228)

Alkaline stress transforms Madin-Darby canine kidney cells

Pfl�gers Archiv European Journal of Physiology, 1991
Similar to growth factors aldosterone stimulates Na+/H+ exchange in renal target cells leading to cytoplasmic alkalinization. An alkaline intracellular pH reduces the H+ bonds between repressor proteins and DNA leading to the destabilization of the nuclear chromatin.
H, Oberleithner, H J, Westphale, B, Gassner   +2 more
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Transport of choline by Madin-Darby canine kidney cells

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1993
Choline is an essential precursor for the synthesis of phosphatidylcholine, the most abundant phospholipid classes in renal cells, as well as for the synthesis of the osmolyte glycerophosphorylcholine. The characteristics of choline uptake in the renal epithelial cell line MDCK were investigated.
P, Zlatkine, G, Moll, A, Blais, A, Loiseau, C, Le Grimellec   +4 more
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Cyclooxygenase expression in canine platelets and Madin-Darby canine kidney cells

American Journal of Veterinary Research, 2000
Abstract Objective—To examine cyclooxygenase (COX) expression in canine platelets and Madin-Darby canine kidney (MDCK) cells in culture. Sample Population—Canine platelets and MDCK cells. Procedure—Total RNA was recovered from isolated canine platelets and MDCK cells.
P A, Kay-Mugford, S J, Benn, J, LaMarre, P D, Conlon   +3 more
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Apparent chloride conductance of subconfluent Madin Darby canine kidney cells

Pfl�gers Archiv European Journal of Physiology, 1986
In incompletely confluent Madin Darby canine kidney (MDCK)-cells continuous measurements of the potential difference across the cell membrane (PD) were made with conventional microelectrodes during rapid changes of extracellular chloride concentration. During control conditions mimicking in vivo situation, PD averages -50.3 +/- 0.7 mV.
F, Lang, M, Defregger, M, Paulmichl
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Zinc alters actin filaments in Madin-Darby canine kidney cells

Toxicology and Applied Pharmacology, 1992
Exposure of semiconfluent cultures of Madin-Darby canine kidney cells to 10 microM zinc leads to a change in the organization of the actin filament system. Most of the stress fibers at the basal end of the cell are lost and the actin associated with the lateral membrane and junctional regions appears to retract into the cytoplasm.
J W, Mills, J H, Zhou, L, Cardoza, V H, Ferm   +3 more
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Bradykinin-evoked Ca2+ mobilization in Madin Darby canine kidney cells

European Journal of Pharmacology, 1998
We studied the mechanisms underlying the bradykinin-evoked changes in intracellular calcium concentration ([Ca2+]i) in Madin Darby canine kidney (MDCK) cells. Bradykinin evoked a [Ca2+]i transient in a dose-dependent manner, measured by fura-2 fluorimetry and digital video imaging.
C R, Jan, C M, Ho, S N, Wu, C J, Tseng
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Fluoxetine-induced Ca 2+ signals in Madin-Darby canine kidney cells

Naunyn-Schmiedeberg's Archives of Pharmacology, 2001
The effect of fluoxetine on Ca2+ signaling in Madin-Darby canine kidney (MDCK) cells was investigated by using fura-2 as a Ca2+ probe. Fluoxetine increased [Ca2+]i concentration-dependently between 5 microM and 200 microM with an EC50 value of 40 microM. The response was reduced by external Ca2+ removal by 30%40%.
K Y, Tang, J S, Cheng, K C, Lee, K J, Chou, J K, Huang, W C, Chen, C R, Jan   +6 more
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[31] Characterization of hormone-sensitive Madin—Darby canine kidney cells

1985
Cultured cells, especially the established lines, provide a continuous and homogeneous system for studying hormone action in intact cells. The cell line known as Madin–Darby canine kidney (MDCK) cells, derived from normal dog kidney more than 20 years ago, is ideal for this type of research, because it retains differentiated functions in culture and ...
Lin, MC, Beckner, SK, Darfler, FJ
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Secretion of proteases in serglycin transfected Madin–Darby canine kidney cells

The FEBS Journal, 2006
Madin–Darby canine kidney (MDCK) cells, which do not normally express the proteoglycan (PG) serglycin, were stably transfected with cDNA for human serglycin fused to a polyhistidine tag (His‐tag). Clones with different levels of serglycin mRNA expression were generated.
Lillian, Zernichow, Knut T, Dalen, Kristian, Prydz, Jan-Olof, Winberg, Svein O, Kolset   +4 more
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Purinoceptor-stimulated phosphoinositide hydrolysis in Madin-Darby canine kidney (MDCK) cells

Naunyn-Schmiedeberg's Archives of Pharmacology, 1997
Extracellular nucleotides, acting through P2-purinoceptors, have been implicated in the regulation of ion transport in epithelia, including Madin-Darby canine kidney (MDCK) cells. In this study, experiments were conducted to characterize the P2-purinoceptor subtype on MDCK cells responsible for stimulating inositol phosphate (IP) accumulation using a ...
C M, Yang, Y J, Tsai, S L, Pan, C T, Tsai, W B, Wu, C T, Chiu, S F, Luo, J T, Ou   +7 more
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