Results 81 to 90 of about 20,289 (228)

AMP‐dependent kinase stimulates the expression of αKlotho

open access: yesFEBS Open Bio
Renal αKlotho along with fibroblast growth factor 23 regulates phosphate and vitamin D metabolism. Its cleavage yields soluble Klotho controlling intracellular processes.
Julia Vogt   +4 more
doaj   +1 more source

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

open access: yesAdvanced Science, Volume 13, Issue 9, 13 February 2026.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang   +13 more
wiley   +1 more source

Polarity of neutral glycolipids, gangliosides, and sulfated lipids in MDCK epithelial cells.

open access: yesJournal of Lipid Research, 1988
Confluent monolayers of MDCK (Madin-Darby canine kidney) cells provide a widely used model system for studying epithelial cell polarity. We determined the polarity of epithelial cell plasma membrane glycolipids and sulfated lipids by analyzing the lipids
G E Nichols, T Shiraishi, W W Young, Jr
doaj   +1 more source

Enhancing the yield of seasonal influenza viruses through manipulation of microRNAs in Madin-Darby canine kidney cells. [PDF]

open access: yesExp Biol Med (Maywood), 2022
Saengchoowong S   +8 more
europepmc   +1 more source

Calcium transients trigger switch-like discharge of prostaglandin E2 in an extracellular signal-regulated kinase-dependent manner

open access: yeseLife
Prostaglandin E2 (PGE2) is a key player in a plethora of physiological and pathological events. Nevertheless, little is known about the dynamics of PGE2 secretion from a single cell and its effect on the neighboring cells.
Tetsuya Watabe   +6 more
doaj   +1 more source

Effect of Riluzole on Ca2+ Movement and Cytotoxicity in Madin-Darby Canine Kidney Cells [PDF]

open access: bronze, 2006
WC Chen   +9 more
openalex   +1 more source

Membrane assembly of Shiga toxin glycosphingolipid receptors and toxin refractiveness of MDCK II epithelial cells

open access: yesJournal of Lipid Research, 2018
Shiga toxins (Stxs) are the major virulence factors of Stx-producing Escherichia coli (STEC), which cause hemorrhagic colitis and severe extraintestinal complications due to injury of renal endothelial cells, resulting in kidney failure.
Nadine Legros   +7 more
doaj   +1 more source

Evaluation of the bioavailability of major withanolides of Withania somnifera using an in vitro absorption model system

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2015
Withania somnifera (L.) Dunal, shows several pharmacological properties which are attributed mainly to the withanolides present in the root. The efficacy of medicinally active withanolides constituents depends on the absorption and transportation through
Santosh T Devkar   +8 more
doaj   +1 more source

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